Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Lukas Rob"'
Autor:
Lenka Kasikova, Jana Rakova, Michal Hensler, Tereza Lanickova, Jana Tomankova, Josef Pasulka, Jana Drozenova, Katerina Mojzisova, Anna Fialova, Sarka Vosahlikova, Jan Laco, Ales Ryska, Pavel Dundr, Roman Kocian, Tomas Brtnicky, Petr Skapa, Linda Capkova, Marek Kovar, Jan Prochazka, Ivan Praznovec, Vladimir Koblizek, Alice Taskova, Hisashi Tanaka, Robert Lischke, Fernando Casas Mendez, Jiri Vachtenheim, Viola Heinzelmann-Schwarz, Francis Jacob, Iain A. McNeish, Michal J. Halaska, Lukas Rob, David Cibula, Sandra Orsulic, Lorenzo Galluzzi, Radek Spisek, Jitka Fucikova
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Intratumoral tertiary lymphoid structures (TLSs) have been associated with improved outcome in various cohorts of patients with cancer, reflecting their contribution to the development of tumor-targeting immunity. Here, we demonstrate that h
Externí odkaz:
https://doaj.org/article/51ecc26da57243349eb37f9d6e8d150d
Autor:
Anna Babkova, Helena Robova, Hana Malikova, Jana Drozenova, Tomas Pichlik, Michael J. Halaska, Lukas Rob
Publikováno v:
Gynecologic Oncology Reports, Vol 56, Iss , Pp 101532- (2024)
The incidence of cancer during pregnancy is steadily rising because of the postponement of plans for childbearing. One of the most common cancers diagnosed during pregnancy is cervical cancer. Diagnosis of most cases usually occurs in the early stage
Externí odkaz:
https://doaj.org/article/645c82f3ed5e40c5b7bfa1b30221cb86
Publikováno v:
Diagnostics, Vol 14, Iss 8, p 810 (2024)
In this study, we reviewed CT/MRI scans and studied the rates of radiation-related fractures in subjects treated for cervical cancer (CC, 63 subjects) by radical radiotherapy (RT) and in subjects treated for endometrial cancer (EC, 64 subjects) by ra
Externí odkaz:
https://doaj.org/article/57d74520879c42b6911e615055e7f94d
Autor:
Karolina Seborova, Viktor Hlavac, Petr Holy, Sunniva S. Bjørklund, Thomas Fleischer, Lukas Rob, Martin Hruda, Jiri Bouda, Marcela Mrhalova, Mohammad Moufaq Khatar Al Obeed Allah, Pavel Vodicka, Ondrej Fiala, Pavel Soucek, Vessela N. Kristensen, Ludmila Vodickova, Radka Vaclavikova
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Epithelial ovarian carcinoma (EOC) is known for high mortality due to diagnosis at advanced stages and frequent therapy resistance. Previous findings suggested that the DNA repair system is involved in the therapeutic response of cancer patients and
Externí odkaz:
https://doaj.org/article/4d3c2d1b733a4311bfac5bc44475ebba
Autor:
Michal Hensler, Jana Rakova, Lenka Kasikova, Tereza Lanickova, Josef Pasulka, Peter Holicek, Marek Hraska, Tereza Hrnciarova, Pavla Kadlecova, Andreu Schoenenberger, Klara Sochorova, Daniela Rozkova, Ludek Sojka, Jana Drozenova, Jan Laco, Rudolf Horvath, Michal Podrazil, Guo Hongyan, Tomas Brtnicky, Michal J. Halaska, Lukas Rob, Ales Ryska, An Coosemans, Ignace Vergote, Abhishek D. Garg, David Cibula, Jirina Bartunkova, Radek Spisek, Jitka Fucikova
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Dendritic cells (DCs) have received considerable attention as potential targets for the development of novel cancer immunotherapies. However, the clinical efficacy of DC-based vaccines remains suboptimal, largely reflecting local and systemic immunos
Externí odkaz:
https://doaj.org/article/8aa6cc35d16f49fbb0529e5fcefe2e0f
Autor:
David Cibula, Pawel Knapp, Bohuslav Melichar, Jiřina Bartůňková, Radek Špíšek, Lukas Rob, Jitka Fucikova, Peter Mallmann, Lubos Minar, Marek Pluta, Jaroslav Klát, Jirí Špacek, Pavel Bartos, Josef Chovanec, Petr Valha, Zdenek Novotny, Dariusz Kieszko, Tereza Hrnciarova, Roman Pawel Korolkiewicz, Marek Hraska
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/54582ca5443540829196267e9ec3d8e8
Autor:
Lenka Kasikova, Michal Hensler, Iva Truxova, Petr Skapa, Jan Laco, Lucie Belicova, Ivan Praznovec, Sarka Vosahlikova, Michael J. Halaska, Tomas Brtnicky, Lukas Rob, Jiri Presl, Jan Kostun, Isabelle Cremer, Ales Ryska, Guido Kroemer, Lorenzo Galluzzi, Radek Spisek, Jitka Fucikova
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Background Adjuvanticity, which is the ability of neoplastic cells to deliver danger signals, is critical for the host immune system to mount spontaneous and therapy-driven anticancer immune responses. One of such signals, i.e., the exposure
Externí odkaz:
https://doaj.org/article/dd34c6ab408e4a95a1f9593ae45f4fa1
Autor:
Sona Hubackova, Miroslav Pribyl, Lenka Kyjacova, Alena Moudra, Rastislav Dzijak, Barbora Salovska, Hynek Strnad, Vojtech Tambor, Terezie Imrichova, Jiri Svec, Pavel Vodicka, Radka Vaclavikova, Lukas Rob, Jiri Bartek, Zdenek Hodny
Publikováno v:
Molecular Oncology, Vol 13, Iss 7, Pp 1467-1489 (2019)
Radiation and chemotherapy represent standard‐of‐care cancer treatments. However, most patients eventually experience tumour recurrence, treatment failure and metastatic dissemination with fatal consequences. To elucidate the molecular mechanisms
Externí odkaz:
https://doaj.org/article/245b820657594210941ebc8f6ccbec17
Autor:
Karolina Seborova, Radka Vaclavikova, Pavel Soucek, Katerina Elsnerova, Alena Bartakova, Petr Cernaj, Jiri Bouda, Lukas Rob, Martin Hruda, Pavel Dvorak
Publikováno v:
Cancer Medicine, Vol 8, Iss 2, Pp 606-616 (2019)
Abstract Introduction Ovarian cancer (OC) represents a serious disease with high mortality and lack of efficient predictive and prognostic biomarkers. ATP‐binding cassette (ABC) proteins constitute a large family dedicated to active transmembrane t
Externí odkaz:
https://doaj.org/article/4226b8e44ddc49938d5292df14cafd04
Autor:
Iva Truxova, Lenka Kasikova, Michal Hensler, Petr Skapa, Jan Laco, Ladislav Pecen, Lucie Belicova, Ivan Praznovec, Michael J. Halaska, Tomas Brtnicky, Eva Salkova, Lukas Rob, Roman Kodet, Jeremy Goc, Catherine Sautes-Fridman, Wolf Herman Fridman, Ales Ryska, Lorenzo Galluzzi, Radek Spisek, Jitka Fucikova
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-13 (2018)
Abstract A high density of tumor-infiltrating CD8+ T cells and CD20+ B cells correlates with prolonged survival in patients with a wide variety of human cancers, including high-grade serous ovarian carcinoma (HGSC). However, the potential impact of m
Externí odkaz:
https://doaj.org/article/0ee748c3b81c416998552dbbd4280c8a