Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lukas Rambousek"'
Autor:
Antonella Zirotti Rosenberg, Maxs Méndez-Ruette, Mario Gorziglia, Benjamín Alzerreca, Javiera Cabello, Sofía Kaufmann, Lukas Rambousek, Andrés Iturriaga Jofré, Ursula Wyneken, Carlos A. Lafourcade
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Epilepsy is a disabling, chronic brain disease,affecting ~1% of the World’s population, characterized by recurrent seizures (sudden, uncontrolled brain activity), which may manifest with motor symptoms (e.g., convulsions) or non-motor symptoms. Tem
Externí odkaz:
https://doaj.org/article/87450fc2404c4795bda9100f034b8d0e
Autor:
Carlos Lafourcade, Jean-Marc Fritschy, Linda Dib, Lukas Rambousek, Jean-Charles Paterna, Adriano Fontana, Tilo Gschwind
Publikováno v:
Scientific Reports, 10 (1)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Epilepsy is a widespread neurological disease characterized by abnormal neuronal activity resulting in recurrent seizures. There is mounting evidence that a circadian system disruption, involving clock genes and their downstream transcriptional regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd211ab206b7528d785b6ba7a51dcf2
https://hdl.handle.net/20.500.11850/404965
https://hdl.handle.net/20.500.11850/404965
Publikováno v:
European journal of pharmacology. 881
Neuroactive steroid 20-oxo-5β-pregnan-3α-yl L-glutamyl 1-ester (PA-Glu), a synthetic analogue of naturally occurring 20-oxo-5β-pregnan-3α-yl sulfate (pregnanolone sulfate, PA-S), inhibits N-methyl-D-aspartate (NMDA) receptors and possesses neurop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9dde0245cb771dac77feee18029f573
https://pubmed.ncbi.nlm.nih.gov/32446713
https://pubmed.ncbi.nlm.nih.gov/32446713
Autor:
Jean-Marc Fritschy, Daniel Jirák, Karel Vales, A. Kubesova, Lukas Rambousek, Lenka Kleteckova
Publikováno v:
Neuropharmacology. 105:594-606
Excessive stimulation of NMDA receptors with glutamate or other potent agonists such as NMDA leads to excitotoxicity and neural injury. In this study, we aimed to provide insight into an animal model of brain excitotoxic damage; single unilateral inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48d6617e8451af996547cb570556988c
https://doi.org/10.1016/j.neuropharm.2016.02.035
https://doi.org/10.1016/j.neuropharm.2016.02.035
Autor:
Irene Knuesel, Tilo Gschwind, Carlos Lafourcade, Lukas Rambousek, Jean-Marc Fritschy, Mariana Zaichuk, Tim Gfeller
Publikováno v:
The European journal of neuroscience. 47(12)
Aberrant epileptic activity is detectable at early disease stages in Alzheimer's disease (AD) patients and in AD mouse models. Here, we investigated in young ArcticAβ mice whether AD-like pathology renders neuronal networks more susceptible to the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1153392966315ea7a2673fa23cfb894a
https://pubmed.ncbi.nlm.nih.gov/29862588
https://pubmed.ncbi.nlm.nih.gov/29862588
Autor:
Vera Bubenikova-Valesova, Kamila Syslová, Lukas Rambousek, Jakub Bumba, Petr Kačer, Romana Šlamberová
Publikováno v:
Drug and Alcohol Dependence. 139:138-144
Background: Methamphetamine (METH) abuse is a growing health problem worldwide, and METH use during pregnancy not only endangers the mother’s health but also the developing fetus. To provide better insight into these risks, we performed the followi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7aeb7091d6534b54e29b28e96dbeec
https://doi.org/10.1016/j.drugalcdep.2014.03.023
https://doi.org/10.1016/j.drugalcdep.2014.03.023
Autor:
Lukas Rambousek, Jan Svoboda, Ladislav Vyklicky, Kristina Holubova, Hana Chodounska, Vera Bubenikova-Valesova, Ales Stuchlik, Karel Vales
Publikováno v:
Behavioural Brain Research. 235:82-88
Neuroactive steroids modulate receptors for neurotransmitters in the brain and thus might be efficacious in the treatment of various diseases of the central nervous system such as schizophrenia. We have designed and synthetized a novel use-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353d1f9b4554d8a2a1f1ec92cdaff7de
https://doi.org/10.1016/j.bbr.2012.07.020
https://doi.org/10.1016/j.bbr.2012.07.020
Autor:
Lukas Rambousek, Tomáš Páleníček, Jiří Horáček, Martin Brunovský, A. Kubesova, Ingmar Gorman, Marie Balíková, Petr Zach, Filip Tylš, M. Fujakova, Cyril Höschl, Petr Kačer, Jana Puskarčíková, Kamila Syslová, Věra Bubeníková-Valešová
Publikováno v:
Psychopharmacology. 225:75-93
Behavioral, neurochemical and pharmaco-EEG profiles of a new synthetic drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in rats were examined.Locomotor effects, prepulse inhibition (PPI) of acoustic startle reaction (ASR), dopamine and its metabolite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52406d5f7962ad64b8ef0316f15b2e49
https://doi.org/10.1007/s00213-012-2797-7
https://doi.org/10.1007/s00213-012-2797-7
Autor:
Věra Bubeníková-Valešová, Marek Kuzma, Petr Kačer, Věra Najmanová, Lukas Rambousek, Romana Šlamberová, Kamila Syslová
Publikováno v:
Journal of Chromatography A. 1218:3382-3391
A sensitive assay method was developed for a parallel, rapid and precise determination of dopamine and its metabolites, homovanillic acid, 3-methoxytyramine and 3,4-dihydroxyphenylacetic acid, from brain microdialysates. The method consisted of a pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616050e401bba515d421c85182f383ca
https://doi.org/10.1016/j.chroma.2011.02.006
https://doi.org/10.1016/j.chroma.2011.02.006
Autor:
Lukas Rambousek, Petr Kačer, Romana Šlamberová, Kamila Syslová, Věra Bubeníková, Věra Najmanová, Karel Vales
Publikováno v:
Chromatographia. 73:143-149
A rapid and precise LC-ESI-MS-MS method for the parallel identification and quantification of dopamine, serotonin and their metabolites (homovanillic acid, 3-methoxytyramine, 3,4-dihydroxyphenylacetic acid and 5-hydroxyindolacetic acid) from rat brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb35ed33dc394a90efefa8e2dda39985
https://doi.org/10.1007/s10337-011-1959-9
https://doi.org/10.1007/s10337-011-1959-9