Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lukas N. Mueller"'
Autor:
Bernd Bodenmiller, Johan Malmstrom, Bertran Gerrits, David Campbell, Henry Lam, Alexander Schmidt, Oliver Rinner, Lukas N Mueller, Paul T Shannon, Patrick G Pedrioli, Christian Panse, Hoo‐Keun Lee, Ralph Schlapbach, Ruedi Aebersold
Publikováno v:
Molecular Systems Biology, Vol 3, Iss 1, Pp 1-11 (2007)
Abstract The ability to analyze and understand the mechanisms by which cells process information is a key question of systems biology research. Such mechanisms critically depend on reversible phosphorylation of cellular proteins, a process that is ca
Externí odkaz:
https://doaj.org/article/eb5ba1ab14134654b28e60760dcd438b
Autor:
Lukas N. Mueller, Ruedi Aebersold, Delphine Pflieger, Uwe Konietzko, Roger M. Nitsch, Bernhard M. Kohli, Giovanni Carbonetti
Publikováno v:
Journal of proteome research
Knowledge of the protein networks interacting with the amyloid precursor protein (APP) in vivo can shed light on the physiological function of APP. To date, most proteins interacting with the APP intracellular domain (AICD) have been identified by Ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3594a27ab3ec0f64b018d9fbe013c1d0
https://doi.org/10.1021/pr300123g
https://doi.org/10.1021/pr300123g
Publikováno v:
Cell. 138(4):795-806
The rise of systems biology implied a growing demand for highly sensitive techniques for the fast and consistent detection and quantification of target sets of proteins across multiple samples. This is only partly achieved by classical mass spectrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ee3fd6ec5266c7ab2a7af6d740f63f
Autor:
Ruedi Aebersold, Lukas N. Mueller, Julian D. Watts, Hamid Mirzaei, Mi Youn Brusniak, Simon Letarte
Publikováno v:
Molecular & Cellular Proteomics. 8:1934-1946
As the application for quantitative proteomics in the life sciences has grown in recent years, so has the need for more robust and generally applicable methods for quality control and calibration. The reliability of quantitative proteomics is tightly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9e5e5a471c54d88f35d448c56d920e4
https://doi.org/10.1074/mcp.m800569-mcp200
https://doi.org/10.1074/mcp.m800569-mcp200
Autor:
Lukas N. Mueller, Ruedi Aebersold, Alexander Schmidt, Markus Mueller, Bruno Domon, D. Campbell, Nils Gehlenborg, Bernd Bodenmiller
Publikováno v:
Molecular & Cellular Proteomics. 7:2138-2150
LC-MS/MS has emerged as the method of choice for the identification and quantification of protein sample mixtures. For very complex samples such as complete proteomes, the most commonly used LC-MS/MS method, data-dependent acquisition (DDA) precursor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd0a9a739340e831253aec14f834051
https://doi.org/10.1074/mcp.m700498-mcp200
https://doi.org/10.1074/mcp.m700498-mcp200
Autor:
James S. Eddes, Paul Shannon, Mi Youn Brusniak, Lukas N. Mueller, Julian D. Watts, Olga Vitek, Christopher J. Kemp, David S. Campbell, Hui Zhang, Alexander Schmidt, Simon Letarte, Ruedi Aebersold, Karen S. Kelly-Spratt, Hollis Lau
Publikováno v:
Clinical Proteomics. 4:105-116
IntroductionA proof-of-concept demonstration of the use of label-free quantitative glycoproteomics for biomarker discovery workflow is presented in this paper, using a mouse model for skin cancer as an example.Materials and MethodsBlood plasma was co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52b1de31e1d59a81914b2213aa13d5f
https://doi.org/10.1007/s12014-008-9018-8
https://doi.org/10.1007/s12014-008-9018-8
Publikováno v:
Journal of Proteome Research. 7:51-61
Over the past decade, a series of experimental strategies for mass spectrometry based quantitative proteomics and corresponding computational methodology for the processing of the resulting data have been generated. We provide here an overview of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b617ab70aa85ebdec45052ab1dc29b6
https://doi.org/10.1021/pr700758r
https://doi.org/10.1021/pr700758r
Autor:
Hamid, Mirzaei, Mi-Youn, Brusniak, Lukas N, Mueller, Simon, Letarte, Julian D, Watts, Ruedi, Aebersold
Publikováno v:
Molecularcellular proteomics : MCP. 8(8)
As the application for quantitative proteomics in the life sciences has grown in recent years, so has the need for more robust and generally applicable methods for quality control and calibration. The reliability of quantitative proteomics is tightly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0687966f1ff82b17a930ecc94facd705
https://pubmed.ncbi.nlm.nih.gov/19411281
https://pubmed.ncbi.nlm.nih.gov/19411281
Autor:
Bernd Wollscheid, Ruedi Aebersold, Lukas N. Mueller, Ralph Schiess, Markus Mueller, Alexander Schmidt
We present a mass spectrometry-based strategy for the specific detection and quantification of cell surface proteome changes. The method is based on the label-free quantification of peptide patterns acquired by high mass accuracy mass spectrometry us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1432f480978b949763eaacfc313dd6
https://europepmc.org/articles/PMC2667347/
https://europepmc.org/articles/PMC2667347/
Autor:
Yves Nyfeler, Ruedi Aebersold, Simon Urwyler, Lukas N. Mueller, Curdin Ragaz, Hubert Hilbi, Hookeun Lee
Publikováno v:
Traffic (Copenhagen, Denmark). 10(1)
Legionella pneumophila, the causative agent of Legionnaires’ disease, replicates in macrophages and amoebae within ‘Legionella-containing vacuoles’ (LCVs), which communicate with the early secretory pathway and the endoplasmic reticulum. Format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4748be1882852e0d4cfafdbea6480ff8
https://pubmed.ncbi.nlm.nih.gov/18980612
https://pubmed.ncbi.nlm.nih.gov/18980612