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Autor:
Paulo W. Pires, Allison M Kath, Michael T. Gee, Juliana L Sacoman, Emily C Peters, Felipe D Polk, Christopher J. Vance, Lukas N Pawlowski
Publikováno v:
J Cereb Blood Flow Metab
Transient increases in intracellular Ca2+ activate endothelium-dependent vasodilatory pathways. This process is impaired in cerebral amyloid angiopathy, where amyloid- β(1-40) accumulates around blood vessels. In neurons, amyloid- β impairs the Ca2