Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Lukas Muri"'
Autor:
Emma Ispasanie, Lukas Muri, Marc Schmid, Anna Schubart, Christine Thorburn, Natasa Zamurovic, Thomas Holbro, Michael Kammüller, Gerd Pluschke
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSeveral diseases caused by the dysregulation of complement activation can be treated with inhibitors of the complement components C5 and/or C3. However, complement is required for serum bactericidal activity (SBA) against encapsulated Gra
Externí odkaz:
https://doaj.org/article/98f0748c5c004296ac5b23564869901e
Autor:
Lukas Muri, Anna Schubart, Christine Thorburn, Natasa Zamurovic, Thomas Holbro, Michael Kammüller, Gerd Pluschke, Emma Ispasanie
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Defense against Haemophilus influenzae type b (Hib) is dependent on antibodies and complement, which mediate both serum bactericidal activity (SBA) and opsonophagocytosis. Here we evaluated the influence of capsule-specific antibodies and complement
Externí odkaz:
https://doaj.org/article/4b7cdba275ec434c86e39c3f02799783
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-9 (2020)
Abstract Background Pneumococcal meningitis (PM) remains a global public health concern and affects all age groups. If acquired during infancy or childhood, permanent neurofunctional deficits including cognitive impairment, cerebral palsy, and second
Externí odkaz:
https://doaj.org/article/8902cb673f5d4223995ad4a32a60ebd1
Autor:
Emma Ispasanie, Lukas Muri, Anna Schubart, Christine Thorburn, Natasa Zamurovic, Thomas Holbro, Michael Kammüller, Gerd Pluschke
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Dysregulation of complement activation causes a number of diseases, including paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome. These conditions can be treated with monoclonal antibodies (mAbs) that bind to the complement co
Externí odkaz:
https://doaj.org/article/738a9b24a2a8447095dcef2b7ca6d73f
Autor:
Lukas Muri, Emma Ispasanie, Anna Schubart, Christine Thorburn, Natasa Zamurovic, Thomas Holbro, Michael Kammüller, Gerd Pluschke
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
To assess the relative contribution of opsonisation by antibodies, classical and alternative complement pathways to pneumococcal phagocytosis, we analyzed killing of pneumococci by human blood leukocytes collected from vaccine-naïve and PCV13-vaccin
Externí odkaz:
https://doaj.org/article/b9295bf56f22447e8d94a836689a5a13
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-14 (2019)
Abstract Background Pneumococcal meningitis is associated with high risk of neurological sequelae such as cognitive impairment and hearing loss. These sequelae are due to parenchymal brain and inner ear damage primarily induced by the excessive infla
Externí odkaz:
https://doaj.org/article/41f13a51d7c3461e8599a33658a311ee
Autor:
Lukas Muri, Simone Oberhänsli, Michelle Buri, Ngoc Dung Le, Denis Grandgirard, Rémy Bruggmann, René M Müri, Stephen L Leib
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0232863 (2020)
Pneumococcal meningitis (PM) causes damage to the hippocampus, a brain structure critically involved in learning and memory. Hippocampal injury-which compromises neurofunctional outcome-occurs as apoptosis of progenitor cells and immature neurons of
Externí odkaz:
https://doaj.org/article/cea61d81be134c0691fd0daecddf3f26
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-14 (2018)
Abstract Background Pneumococcal meningitis is associated with high mortality and morbidity rates. Up to 50% of survivors show neurologic sequelae including hearing loss, cognitive impairments and learning disabilities, being particularly detrimental
Externí odkaz:
https://doaj.org/article/25e5682741d24ded875b64f39669b8e3
Autor:
Gierin Thomi, Marianne Joerger-Messerli, Valérie Haesler, Lukas Muri, Daniel Surbek, Andreina Schoeberlein
Publikováno v:
Cells, Vol 8, Iss 8, p 855 (2019)
Perinatal brain injury (PBI) in preterm birth is associated with substantial injury and dysmaturation of white and gray matter, and can lead to severe neurodevelopmental deficits. Mesenchymal stromal cells (MSC) have been suggested to have neuroprote
Externí odkaz:
https://doaj.org/article/6570fe08d470492b8dd2a6f4b0166f35
Autor:
Thomas Holbro, Emma Ispasanie, Michael Kammüller, Gerd Pluschke, Christine Thorburn, Natasa Zamurovic, Anna Schubart, Lukas Muri
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
To assess the relative contribution of opsonisation by antibodies, classical and alternative complement pathways to pneumococcal phagocytosis, we analyzed killing of pneumococci by human blood leukocytes collected from vaccine-naïve and PCV13-vaccin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d0995fc39d201de2bbc63646960679
http://europepmc.org/articles/PMC8543009
http://europepmc.org/articles/PMC8543009