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Autor:
Lukas Matthaeus Altenburger, Yosuke Harada, Philippe Dehio, Nora Ruef, Matthias Mehling, Jens Volker Stein
Publikováno v:
The Journal of Immunology. 206:98.29-98.29
Naïve T cells and dendritic cells (DCs) are drawn to lymphoid tissue by the chemokine receptor CCR7, where its ligands CCL19 and CCL21 are secreted by lymphoid stroma. There, CCR7 fuels the fast migration of naïve T cells to expedite encounters wit