Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lukas Maria Gockel"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3323 (2021)
Pancreatic cancer patients have an elevated risk of suffering from venous thrombosis. Among several risk factors that contribute to hypercoagulability of this malignancy, platelets possess a key role in the initiation of clot formation. Although sing
Externí odkaz:
https://doaj.org/article/923ad1897b4d437f82ae0e1be6cdad90
Autor:
Svenja Schwarz, Lukas Maria Gockel, Annamaria Naggi, Uri Barash, Martina Gobec, Gerd Bendas, Martin Schlesinger
Publikováno v:
Molecules, Vol 25, Iss 5, p 1039 (2020)
Tumor cell−platelet interactions are regarded as an initial crucial step in hematogenous metastasis. Platelets protect tumor cells from immune surveillance in the blood, mediate vascular arrest, facilitate tumor extravasation, growth, and finally a
Externí odkaz:
https://doaj.org/article/3ba7bb0036474ba19c1f74dacb97dc1c
Publikováno v:
Molecules, Vol 23, Iss 11, p 2753 (2018)
An intimate interplay with platelets is an initial key issue for tumor cells in terms of hematogenous metastasis. Tumor cells activate platelets by different pathways and receive, upon forming a platelet cloak, protection from immune surveillance and
Externí odkaz:
https://doaj.org/article/537847fa22d94d248e1d846480fa15a2
Publikováno v:
Molecules, Vol 23, Iss 10, p 2690 (2018)
The interaction with platelets is of crucial importance for tumor cells passing through hematogenous metastasis. Platelets protect cancer cells from immune surveillance and exhibit many other prometastatic effects. Notably, platelets can change the e
Externí odkaz:
https://doaj.org/article/f813b550d3214f0cb95b548f45a0fd3b
Autor:
Gerd Bendas, Abdullah Al Nahain, Martin Heyes, Vito Ferro, Lukas Maria Gockel, Jin-Ping Li, Honglian Li, Stefan Holdenrieder, Christian Gorzelanny, Martin Schlesinger
Publikováno v:
ACS Applied Materials & Interfaces. 13:7080-7093
Low-molecular-weight heparin (LMWH) is the guideline-based drug for antithrombotic treatment of cancer patients, while its direct antitumor effects are a matter of ongoing debate. Although therapeutically established for decades, LMWH has several dra
Autor:
Annamaria Naggi, Gerd Bendas, Martin Schlesinger, Martina Gobec, Svenja Schwarz, Uri Barash, Lukas Maria Gockel
Publikováno v:
Molecules
Molecules, Vol 25, Iss 5, p 1039 (2020)
Volume 25
Issue 5
Molecules, Vol 25, Iss 5, p 1039 (2020)
Volume 25
Issue 5
Tumor cell&ndash
platelet interactions are regarded as an initial crucial step in hematogenous metastasis. Platelets protect tumor cells from immune surveillance in the blood, mediate vascular arrest, facilitate tumor extravasation, growth, and
platelet interactions are regarded as an initial crucial step in hematogenous metastasis. Platelets protect tumor cells from immune surveillance in the blood, mediate vascular arrest, facilitate tumor extravasation, growth, and
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 3323, p 3323 (2021)
Volume 22
Issue 7
International Journal of Molecular Sciences, Vol 22, Iss 3323, p 3323 (2021)
Volume 22
Issue 7
Pancreatic cancer patients have an elevated risk of suffering from venous thrombosis. Among several risk factors that contribute to hypercoagulability of this malignancy, platelets possess a key role in the initiation of clot formation. Although sing
Autor:
Manuel Grundmann, Sebastian G. Hoß, Israel Vlodavsky, Neta Ilan, Martin Schlesinger, Lukas Maria Gockel, Svenja Schwarz, Tobias Benkel, Evi Kostenis, Gerd Bendas
Publikováno v:
Thrombosis and haemostasis. 118(10)
Heparanase (HPSE) is an endo-β-D-glucuronidase that cleaves heparan sulphate (HS) chains of proteoglycans (HSPGs). Besides a remodelling of the extracellular matrix, HPSE increases the bioavailability of pro-angiogenic mediators, such as HS-associat
Publikováno v:
Molecules
Volume 23
Issue 11
Molecules, Vol 23, Iss 11, p 2753 (2018)
Volume 23
Issue 11
Molecules, Vol 23, Iss 11, p 2753 (2018)
An intimate interplay with platelets is an initial key issue for tumor cells in terms of hematogenous metastasis. Tumor cells activate platelets by different pathways and receive, upon forming a platelet cloak, protection from immune surveillance and