Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lukas Maas"'
Autor:
Alexander Quaas, Julie George, Philipp Müller, Hans Anton Schlößer, Michael von Bergwelt-Baildon, Martin Thelen, Birgit Gathof, Martin Peifer, Thomas Zander, Axel M Hillmer, Christiane Bruns, Diandra Keller, Jonas Lehmann, Kerstin Wennhold, Eugen Bauer, Maria Alejandra Garcia-Marquez, Roman Thomas, Lukas Maas, Miloš Nikolić, Wolfgang Schröder, Ali M Yazbeck
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background The individual HLA-I genotype is associated with cancer, autoimmune diseases and infections. This study elucidates the role of germline homozygosity or allelic imbalance of HLA-I loci in esophago-gastric adenocarcinoma (EGA) and determines
Externí odkaz:
https://doaj.org/article/afc5d656bb5b494e9b31c5d4b6a0c547
Autor:
Florian Malchers, Lucia Nogova, Martijn H.A. van Attekum, Lukas Maas, Johannes Brägelmann, Christoph Bartenhagen, Luc Girard, Graziella Bosco, Ilona Dahmen, Sebastian Michels, Clare E. Weeden, Andreas H. Scheel, Lydia Meder, Kristina Golfmann, Philipp Schuldt, Janna Siemanowski, Jan Rehker, Sabine Merkelbach-Bruse, Roopika Menon, Oliver Gautschi, Johannes M. Heuckmann, Elisabeth Brambilla, Marie-Liesse Asselin-Labat, Thorsten Persigehl, John D. Minna, Henning Walczak, Roland T. Ullrich, Matthias Fischer, Hans Christian Reinhardt, Jürgen Wolf, Reinhard Büttner, Martin Peifer, Julie George, Roman K. Thomas
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
The discovery of frequent 8p11-p12 amplifications in squamous cell lung cancer (SQLC) has fueled hopes that FGFR1, located inside this amplicon, might be a therapeutic target. In a clinical trial, only 11% of patients with 8p11 amplification (detecte
Externí odkaz:
https://doaj.org/article/ef6247e9f6b84dbca5a0844486ed3d80
Autor:
Diana Schaufler, David F. Ast, Hannah L. Tumbrink, Nima Abedpour, Lukas Maas, Ayla E. Schwäbe, Inga Spille, Stefanie Lennartz, Jana Fassunke, Mihaela Aldea, Benjamin Besse, David Planchard, Lucia Nogova, Sebastian Michels, Carsten Kobe, Thorsten Persigehl, Theresa Westphal, Sophia Koleczko, Rieke Fischer, Jan-Phillip Weber, Janine Altmüller, Roman K. Thomas, Sabine Merkelbach-Bruse, Oliver Gautschi, Laura Mezquita, Reinhard Büttner, Jürgen Wolf, Martin Peifer, Johannes Brägelmann, Matthias Scheffler, Martin L. Sos
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-12 (2021)
Abstract Activation of MAPK signaling via BRAF mutations may limit the activity of EGFR inhibitors in EGFR-mutant lung cancer patients. However, the impact of BRAF mutations on the selection and fitness of emerging resistant clones during anti-EGFR t
Externí odkaz:
https://doaj.org/article/2fe94ce5763c49248add719a2c82fe60
Autor:
Lech Nieroda, Lukas Maas, Scott Thiebes, Ulrich Lang, Ali Sunyaev, Viktor Achter, Martin Peifer
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background The massive amounts of data from next generation sequencing (NGS) methods pose various challenges with respect to data security, storage and metadata management. While there is a broad range of data analysis pipelines, these chall
Externí odkaz:
https://doaj.org/article/bfcbdad7e1bd4ebeb800f8187261aac1
Autor:
Julie George, Vonn Walter, Martin Peifer, Ludmil B. Alexandrov, Danila Seidel, Frauke Leenders, Lukas Maas, Christian Müller, Ilona Dahmen, Tiffany M. Delhomme, Maude Ardin, Noemie Leblay, Graham Byrnes, Ruping Sun, Aurélien De Reynies, Anne McLeer-Florin, Graziella Bosco, Florian Malchers, Roopika Menon, Janine Altmüller, Christian Becker, Peter Nürnberg, Viktor Achter, Ulrich Lang, Peter M. Schneider, Magdalena Bogus, Matthew G. Soloway, Matthew D. Wilkerson, Yupeng Cun, James D. McKay, Denis Moro-Sibilot, Christian G. Brambilla, Sylvie Lantuejoul, Nicolas Lemaitre, Alex Soltermann, Walter Weder, Verena Tischler, Odd Terje Brustugun, Marius Lund-Iversen, Åslaug Helland, Steinar Solberg, Sascha Ansén, Gavin Wright, Benjamin Solomon, Luca Roz, Ugo Pastorino, Iver Petersen, Joachim H. Clement, Jörg Sänger, Jürgen Wolf, Martin Vingron, Thomas Zander, Sven Perner, William D. Travis, Stefan A. Haas, Magali Olivier, Matthieu Foll, Reinhard Büttner, David Neil Hayes, Elisabeth Brambilla, Lynnette Fernandez-Cuesta, Roman K. Thomas
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The molecular nature of large-cell neuroendocrine lung carcinomas (LCNEC) has remained unclear. Here, the authors show LCNECs represent a distinct transcriptional subgroup among lung cancers and comprise two molecular subgroups, type I (TP53 and STK1
Externí odkaz:
https://doaj.org/article/0b984304ba014836a34f2b6d1a57b335
Autor:
Ali Sunyaev, Lech Nieroda, Lukas Maas, Martin Peifer, Ulrich Lang, Viktor Achter, Scott Thiebes
Publikováno v:
BMC Bioinformatics
BMC bioinformatics, 20 (1), Art. Nr.: 29
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-8 (2019)
BMC bioinformatics, 20 (1), Art. Nr.: 29
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-8 (2019)
Background: The massive amounts of data from next generation sequencing (NGS) methods pose various challenges with respect to data security, storage and metadata management. While there is a broad range of data analysis pipelines, these challenges re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1190377a55ade5eaea980589167735
Autor:
Magali Olivier, Sven Perner, Peter Nürnberg, William D. Travis, Viktor Achter, Steinar Solberg, Stefan A. Haas, Elisabeth Brambilla, Ruping Sun, Lynnette Fernandez-Cuesta, Yupeng Cun, Ilona Dahmen, Luca Roz, Anne McLeer-Florin, Graham Byrnes, Denis Moro-Sibilot, Gavin M. Wright, Christian Becker, Åslaug Helland, Tiffany M. Delhomme, Peter M. Schneider, Julie George, Martin Vingron, Walter Weder, Roman K. Thomas, Ludmil B. Alexandrov, Jürgen Wolf, Sylvie Lantuejoul, David N. Hayes, Maude Ardin, James McKay, Christian Brambilla, Roopika Menon, Matthew G. Soloway, Alex Soltermann, Christian Müller, Noémie Leblay, Thomas Zander, Ugo Pastorino, Odd Terje Brustugun, Vonn Walter, Jörg Sänger, Ulrich Lang, Aurélien de Reyniès, Marius Lund-Iversen, Graziella Bosco, Reinhard Büttner, Benjamin Solomon, Sascha Ansén, Matthieu Foll, Verena Tischler, Iver Petersen, Lukas Maas, Janine Altmüller, Joachim H. Clement, Frauke Leenders, Matthew D. Wilkerson, Danila Seidel, Florian Malchers, Magdalena Bogus, Martin Peifer, Nicolas Lemaitre
Publikováno v:
Nature Communications
Nature communications, vol 9, iss 1
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature communications, vol 9, iss 1
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Pulmonary large-cell neuroendocrine carcinomas (LCNECs) have similarities with other lung cancers, but their precise relationship has remained unclear. Here we perform a comprehensive genomic (n = 60) and transcriptomic (n = 69) analysis of 75 LCNECs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3143f41fcfedb2e7fcc6e45c3af60387
https://hdl.handle.net/21.11116/0000-0003-7405-521.11116/0000-0003-7407-3
https://hdl.handle.net/21.11116/0000-0003-7405-521.11116/0000-0003-7407-3