Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Lukas M, Carter"'
Autor:
David Bauer, Hannah Visca, Anuradha Weerakkody, Lukas M. Carter, Zachary Samuels, Spencer Kaminsky, Oleg A. Andreev, Yana K. Reshetnyak, Jason S. Lewis
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Acidosis of the tumor microenvironment is a hallmark of tumor progression and has emerged as an essential biomarker for cancer diagnosis, prognosis, and evaluation of treatment response. A tool for quantitatively visualizing the acidic tumor environm
Externí odkaz:
https://doaj.org/article/23d2a376d1b64ac5821a161c3d785e3f
Autor:
Junior Gonzales, Giacomo Pirovano, Chun Yuen Chow, Paula Demetrio de Souza Franca, Lukas M. Carter, Julie K. Klint, Navjot Guru, Jason S. Lewis, Glenn F. King, Thomas Reiner
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract Background Accidental peripheral nerve injury during surgical intervention results in a broad spectrum of potentially debilitating side effects. Tissue distortion and poor visibility can significantly increase the risk of nerve injury with l
Externí odkaz:
https://doaj.org/article/88cb7901fe984b199220e9001de5571c
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Chimeric antigen receptor (CAR) – and T-cell receptor (TCR) – modified T-cells are rapidly emerging as a viable treatment option for cancer patients. While initial clinical trials for these CAR T cells showed response rates of over 90% in some ca
Externí odkaz:
https://doaj.org/article/312ffd5202004fc391742e1e46e4a7d2
Autor:
Patrícia M. R. Pereira, Sai Kiran Sharma, Lukas M. Carter, Kimberly J. Edwards, Jacob Pourat, Ashwin Ragupathi, Yelena Y. Janjigian, Jeremy C. Durack, Jason S. Lewis
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Trastuzumab binding to tumor cells depends on the availability of HER2 at the cell membrane. Here the authors show that caveolin-1 (CAV1) regulates HER2 density at the cell membranes and that CAV1 gene knockdown or protein depletion via the cholester
Externí odkaz:
https://doaj.org/article/655bc247cda34be5801b730bd0910363
Autor:
Lukas M. Carter, Simone Krebs, Harry Marquis, Juan C. Ocampo Ramos, Edmond A. Olguin, Emilia O. Mason, Wesley E. Bolch, Pat B. Zanzonico, Adam L. Kesner
Publikováno v:
Journal of Nuclear Medicine. 64:782-790
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357137502ce5b8d7cf1758cb3b405577
https://doi.org/10.2967/jnumed.122.264916
https://doi.org/10.2967/jnumed.122.264916
Autor:
Lukas M. Carter, Michael B. Bellamy, Chansoo Choi, Chan Hyeong Kim, Wesley E. Bolch, Derek Jokisch, Adam L. Kesner
Publikováno v:
Health Physics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d885bcd2d167b6f0107ce6e6b7296d13
https://doi.org/10.1097/hp.0000000000001701
https://doi.org/10.1097/hp.0000000000001701
Autor:
Jason S. Lewis, Charles M. Rudin, John T. Poirier, Nagavarakishore Pillarsetty, Triparna Sen, William D. Travis, Alessandra Piersigilli, Avelyn Mae Delos Reyes, Joshua A. Korsen, Komal Mandleywala, Zachary V. Samuels, Sai Kiran Sharma, Lukas M. Carter, Salomon Tendler, Kathryn M. Tully
Purpose:Small cell lung cancer (SCLC) is an exceptionally lethal form of lung cancer with limited treatment options. Delta-like ligand 3 (DLL3) is an attractive therapeutic target as surface expression is almost exclusive to tumor cells.Experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f434032382cffa213eacf1d20935fda
https://doi.org/10.1158/1078-0432.c.6531161
https://doi.org/10.1158/1078-0432.c.6531161
Autor:
Yue-Ming Li, Naga Vara Kishore Pillarsetty, Jason S. Lewis, Lukas M. Carter, Blesida Punzalan, Kelly E. Henry, Georgia Frost, George P. Liao, Thomas Li, Xianzhong Wu, Veronica L. Nagle, Teja Kalidindi, Pengju Nie
Purpose:Abnormal Notch signaling promotes cancer cell growth and tumor progression in various cancers. Targeting γ-secretase, a pivotal regulator in the Notch pathway, has yielded numerous γ-secretase inhibitors (GSIs) for clinical investigation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7fa567cdfaa98b337a9a25705f95ce
https://doi.org/10.1158/1078-0432.c.6530742.v1
https://doi.org/10.1158/1078-0432.c.6530742.v1
Autor:
Jason S. Lewis, Taha Merghoub, Christine A. Iacobuzio-Donahue, Abu-Akeel Mohsen, Lolkje Abma, Mike Cornejo, Luis Felipe Campesato, Freddy E. Escorcia, Lukas M. Carter, Komal Mandleywala, Kimberly J. Edwards, Patricia M.R. Pereira
Pancreatic ductal adenocarcinoma (PDAC) is highly resistant to radiotherapy, chemotherapy, or a combination of these modalities, and surgery remains the only curative intervention for localized disease. Although cancer-associated fibroblasts (CAF) ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::857e7aeabbc522bf4f1b64107d4a174b
https://doi.org/10.1158/0008-5472.c.6511831.v1
https://doi.org/10.1158/0008-5472.c.6511831.v1
Autor:
Jason S. Lewis, Charles M. Rudin, John T. Poirier, Nagavarakishore Pillarsetty, Triparna Sen, William D. Travis, Alessandra Piersigilli, Avelyn Mae Delos Reyes, Joshua A. Korsen, Komal Mandleywala, Zachary V. Samuels, Sai Kiran Sharma, Lukas M. Carter, Salomon Tendler, Kathryn M. Tully
Supplementary Figure from Radioimmunotherapy Targeting Delta-like Ligand 3 in Small Cell Lung Cancer Exhibits Antitumor Efficacy with Low Toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d287ee932905c9f73acd65d57e15e2
https://doi.org/10.1158/1078-0432.22483574
https://doi.org/10.1158/1078-0432.22483574