Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lukas Lauterbach"'
Autor:
Anuj K. Chhalodia, Houchao Xu, Georges B. Tabekoueng, Binbin Gu, Kizerbo A. Taizoumbe, Lukas Lauterbach, Jeroen S. Dickschat
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 1386-1398 (2023)
Fifteen type I terpene synthase homologs from diverse actinobacteria that were selected based on a phylogenetic analysis of more than 4000 amino acid sequences were investigated for their products. For four enzymes with functions not previously repor
Externí odkaz:
https://doaj.org/article/249671d8ce1e4762884092e94967a098
Autor:
Kristina Schell, Heng Li, Lukas Lauterbach, Kizerbo A. Taizoumbe, Jeroen S. Dickschat, Bernhard Hauer
Publikováno v:
ACS Catalysis. 13:5073-5083
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::153b7d606a31c194893e56f75ed4198b
https://doi.org/10.1021/acscatal.2c05949
https://doi.org/10.1021/acscatal.2c05949
Autor:
Hui Tao, Lukas Lauterbach, Guangkai Bian, Rong Chen, Anwei Hou, Takahiro Mori, Shu Cheng, Ben Hu, Li Lu, Xin Mu, Min Li, Naruhiko Adachi, Masato Kawasaki, Toshio Moriya, Toshiya Senda, Xinghuan Wang, Zixin Deng, Ikuro Abe, Jeroen S. Dickschat, Tiangang Liu
Publikováno v:
Nature. 606:414-419
All known triterpenes are generated by triterpene synthases (TrTSs) from squalene or oxidosqualene1. This approach is fundamentally different from the biosynthesis of short-chain (C10–C25) terpenes that are formed from polyisoprenyl diphosphates2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f42f3011a5d64b09e7480bcd53619a
https://doi.org/10.1038/s41586-022-04773-3
https://doi.org/10.1038/s41586-022-04773-3
Publikováno v:
Nature Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95bce577c8da69fbaf57c89c3cb612d7
https://doi.org/10.1038/s41557-023-01223-z
https://doi.org/10.1038/s41557-023-01223-z
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
The dauc‐8‐en‐11‐ol synthase from Streptomyces venezuelae was investigated for its catalytic activity towards alternative terpene precursors, specifically designed to enable new cyclisation pathways. Exchange of aromatic amino acid residues a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0d58bdd288ba55543ff4efd4fee9cc
https://doi.org/10.1002/chem.202100962
https://doi.org/10.1002/chem.202100962
Autor:
Lukas Lauterbach, Jeroen S. Dickschat
Publikováno v:
Chembiochem
The flavobacterium Chryseobacterium polytrichastri was investigated for its volatile profile by use of a closed‐loop stripping apparatus (CLSA) and subsequent GC‐MS analysis. The analyses revealed a rich headspace extract with 71 identified compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed7c8d4336308ddc796314cac4e08b7
https://doi.org/10.1002/cbic.202000503
https://doi.org/10.1002/cbic.202000503
Publikováno v:
Angew Chem Int Ed Engl
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International Ed. in English)
Two bacterial diterpene synthases (DTSs) from Chryseobacterium were characterised. The first enzyme yielded the new compound chryseodiene that closely resembles the known fusicoccane diterpenes from fungi, but its experimentally and computationally s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433d5ee1837507d41844cede626fdd92
https://doi.org/10.1002/anie.202004691
https://doi.org/10.1002/anie.202004691
Autor:
Guo-Dong Chen, Yong-Heng Wang, Jeroen S. Dickschat, Jianming Lv, Fu-Long Lin, Xin Sheng Yao, Jian Zou, Lukas Lauterbach, Dan Hu, Hao Gao
Publikováno v:
ACS Catalysis. 10:4306-4312
Fusicoccane (FC)-type diterpenes, featuring a common 5–8–5 tricyclic skeleton, possess diverse biological functions. Currently, only FC-type diterpene synthases (DTSs) for 3 of the 16 possible ster...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ccdab275725d9b4e08d55ec3c2c46df
https://doi.org/10.1021/acscatal.0c00377
https://doi.org/10.1021/acscatal.0c00377
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Methylated analogues of isopentenyl diphosphate were synthesised and enzymatically incorporated into methylated terpenes. A detailed stereochemical analysis of the obtained products is presented. The methylated terpene precursors were also used in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f12445353ca85dfad0965fce4947d2
http://europepmc.org/articles/PMC7065205
http://europepmc.org/articles/PMC7065205
Autor:
Keiichi Murai, Zhiyang Quan, Kazuro Shiomi, Tsuyoshi Yamamoto, Makoto Nishiyama, Jeroen S. Dickschat, Kenichi Nonaka, Tomohisa Kuzuyama, Lukas Lauterbach, Kazuya Teramoto, Lena Barra
Publikováno v:
Angewandte Chemie. 131:15188-15192
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bced50d15d1049ef2462dfa237cd337
https://doi.org/10.1002/ange.201907964
https://doi.org/10.1002/ange.201907964