Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lukas Kahlert"'
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109572- (2024)
Externí odkaz:
https://doaj.org/article/638c1224672f4b26bbb96ed7bcc0f96e
Autor:
Michael S. Lichstrahl, Lukas Kahlert, Rongfeng Li, Trevor A. Zandi, Jerry Yang, Craig. A. Townsend
Publikováno v:
Chemical Science. 14:3923-3931
A small library of stereochemically-defined α,β-diamino acids has been prepared to generate non-native monobactams through fermentation, highlighting the potential of this platform for directed biosynthesis.
Publikováno v:
ChemBioChem. 24
Adenylation domains are the main contributor to structural complexity among nonribosomal peptides due to their varied but stringent substrate selection. Several in vitro assays to determine the substrate specificity of these dedicated biocatalysts ha
Publikováno v:
Angewandte Chemie (International Ed. in English)
The polyketide synthase (PKS)‐like protein TerB, consisting of inactive dehydratase, inactive C‐methyltransferase, and functional ketoreductase domains collaborates with the iterative non reducing PKS TerA to produce 6‐hydroxymellein, a key pat
Publikováno v:
Synthesis. 53:2381-2394
Total biosynthesis in fungi is beginning to compete with traditional chemical total synthesis campaigns. Herein, the advantages, disadvantages and future opportunities are discussed within the scope of several recent examples.1 Introduction2 Syntheti
Publikováno v:
Angewandte Chemie-International Edition 59 (2020), Nr. 14
The sorbicillinoids are a class of biologically active and structurally diverse fungal polyketides arising from sorbicillin. Through co-expression of sorA, sorB, sorC, and sorD from Trichoderma reesei QM6a, the biosynthetic pathway to epoxysorbicilli
Publikováno v:
Chemical Communications. 56:10934-10937
Sorbicillinoids are a large family of fungal secondary metabolites with a diverse range of structures and numerous bioactivites, some of which have pharmaceutical potential. The flavin-dependent monooxygenase SorD from Penicillium chrysogenum (PcSorD
Publikováno v:
Chembiochem
ChemBioChem : an official journal of the EFMC 22 (2021), Nr. 19
ChemBioChem : an official journal of the EFMC
ChemBioChem : an official journal of the EFMC 22 (2021), Nr. 19
ChemBioChem : an official journal of the EFMC
The valuable aroma compound piperonal with its vanilla‐like olfactory properties is of high interest for the fragrance and flavor industry. A lipoxygenase (LOXPsa1) of the basidiomycete Pleurotus sapidus was identified to convert piperine, the abun
Autor:
Russell J. Cox, Laura P. Ióca, Darlon I. Bernardi, Elizabeth Skellam, Lukas Kahlert, Roberto G. S. Berlinck, Maurice Hauser
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
The mycotoxin terrein is derived from the C10‐precursor 6‐hydroxymellein (6‐HM) via an oxidative ring contraction. Although the corresponding biosynthetic gene cluster (BGC) has been identified, details of the enzymatic oxidative transformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d3bc3b8a47033bb89df99e95f7ca69
Publikováno v:
Angewandte Chemie (International Ed. in English)
The sorbicillinoids are a class of biologically active and structurally diverse fungal polyketides arising from sorbicillin. Through co‐expression of sorA, sorB, sorC, and sorD from Trichoderma reesei QM6a, the biosynthetic pathway to epoxysorbicil