Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Lukas Habernig"'
Autor:
Jutta Diessl, Jens Berndtsson, Filomena Broeskamp, Lukas Habernig, Verena Kohler, Carmela Vazquez-Calvo, Arpita Nandy, Carlotta Peselj, Sofia Drobysheva, Ludovic Pelosi, F.-Nora Vögtle, Fabien Pierrel, Martin Ott, Sabrina Büttner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Across phylae, excess manganese disrupts energy metabolism by unclear mechanisms. Here, Diessl et al. report that failure of mitochondrial bioenergetics upon manganese overload is due to mismetallation of a diiron enzyme crucial for CoQ biosynthesis
Externí odkaz:
https://doaj.org/article/4dc9625ee56c416c8681a2d756ae7db0
Publikováno v:
Microbial Cell, Vol 7, Iss 4, Pp 106-114 (2020)
The protein phosphatase calcineurin is activated in response to rising intracellular Ca2+ levels and impacts fundamental cellular processes in organisms ranging from yeast to humans. In fungi, calcineurin orchestrates cellular adaptation to diverse e
Externí odkaz:
https://doaj.org/article/3ed637a484cf404cb444aef496c08ceb
Autor:
Carlotta Peselj, Mahsa Ebrahimi, Filomena Broeskamp, Simon Prokisch, Lukas Habernig, Irene Alvarez-Guerra, Verena Kohler, F.-Nora Vögtle, Sabrina Büttner
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Nutrient starvation initiates cell cycle exit and entry into quiescence, a reversible, non-proliferative state characterized by stress tolerance, longevity and large-scale remodeling of subcellular structures. Depending on the nature of the depleted
Externí odkaz:
https://doaj.org/article/4d0b1f8ac67b4bb5acd059d5aa24532d
Autor:
Lukas Habernig, Filomena Broeskamp, Andreas Aufschnaiter, Jutta Diessl, Carlotta Peselj, Elisabeth Urbauer, Tobias Eisenberg, Ana de Ory, Sabrina Büttner
Publikováno v:
PLoS Genetics, Vol 17, Iss 11, p e1009911 (2021)
The capacity of a cell to maintain proteostasis progressively declines during aging. Virtually all age-associated neurodegenerative disorders associated with aggregation of neurotoxic proteins are linked to defects in the cellular proteostasis networ
Externí odkaz:
https://doaj.org/article/3275e960d02c424789ab4ab1a2d49e6a
Autor:
Daniel Poveda-Huertes, Asli Aras Taskin, Ines Dhaouadi, Lisa Myketin, Adinarayana Marada, Lukas Habernig, Sabrina Büttner, F-Nora Vögtle
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009664 (2021)
Mitochondrial defects can cause a variety of human diseases and protective mechanisms exist to maintain mitochondrial functionality. Imbalances in mitochondrial proteostasis trigger a transcriptional program, termed mitochondrial unfolded protein res
Externí odkaz:
https://doaj.org/article/4bc527a29d51462a9590e7b42257a8e8
Autor:
Jianli Duan, Yunpo Zhao, Haichao Li, Lukas Habernig, Michael D. Gordon, Xuexia Miao, Ylva Engström, Sabrina Büttner
Publikováno v:
Cell Reports, Vol 32, Iss 4, Pp 107972- (2020)
Summary: Drosophila development is governed by distinct ecdysone steroid pulses that initiate spatially and temporally defined gene expression programs. The translation of these signals into tissue-specific responses is crucial for metamorphosis, but
Externí odkaz:
https://doaj.org/article/57071ab60947417aa145ff09e808609e
Autor:
Tamara Suhm, Lukas Habernig, Magdalena Rzepka, Jayasankar Mohanakrishnan Kaimal, Claes Andréasson, Sabrina Buettner, Martin Ott
Publikováno v:
Microbial Cell, Vol 5, Iss 3, Pp 158-164 (2018)
The mitochondrial genome is responsible for the production of a handful of polypeptides that are core subunits of the membrane-bound oxidative phosphorylation system. Until now the mechanistic studies of mitochondrial protein synthesis inside cells h
Externí odkaz:
https://doaj.org/article/edadacf5656247bbaefb62b1027d7ff6
Autor:
Mahsa Ebrahimi, Lukas Habernig, Filomena Broeskamp, Andreas Aufschnaiter, Jutta Diessl, Isabel Atienza, Steffen Matz, Felix A. Ruiz, Sabrina Büttner
Publikováno v:
Cells, Vol 10, Iss 11, p 3161 (2021)
Nutrient limitation results in an activation of autophagy in organisms ranging from yeast, nematodes and flies to mammals. Several evolutionary conserved nutrient-sensing kinases are critical for efficient adaptation of yeast cells to glucose, nitrog
Externí odkaz:
https://doaj.org/article/66272d53b3b0473b863a7fdb23b8b284
Autor:
Filomena Broeskamp, Elizabeth S. M. Edrich, Oskar Knittelfelder, Lisa Neuhaus, Thorsten Meyer, Jonas Heyden, Lukas Habernig, Florian Kreppel, Campbell W. Gourlay, Patrick Rockenfeller
Publikováno v:
Cells, Vol 10, Iss 9, p 2416 (2021)
Autophagy is a cellular recycling program which efficiently reduces the cellular burden of ageing. Autophagy is characterised by nucleation of isolation membranes, which grow in size and further expand to form autophagosomes, engulfing cellular mater
Externí odkaz:
https://doaj.org/article/1a6f54ffecae44a8a599bd8710dcc9dc
Autor:
Irene Álvarez-Guerra, Emma Block, Filomena Broeskamp, Sonja Gabrijelčič, Ana de Ory, Lukas Habernig, Claes Andréasson, Tim P. Levine, Johanna L. Höög, Sabrina Büttner
SummaryLipid droplets (LDs) are fat storage organelles critical for energy and lipid metabolism. Upon nutrient exhaustion, cells consume LDs via gradual lipolysis or via lipophagy, theen blocuptake of LDs into the vacuole. Here, we show that LDs dock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b26680096546e5f072dd1c6d746267b
https://doi.org/10.1101/2023.04.21.537797
https://doi.org/10.1101/2023.04.21.537797
