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Akademický článek

Patient eligibility for trials with imaging response assessment at the time of molecular tumor board presentation

Autor: Nabeel Mansour, Kathrin Heinrich, Danmei Zhang, Michael Winkelmann, Maria Ingenerf, Lukas Gold, Konstantin Klambauer, Martina Rudelius, Frederick Klauschen, Michael von Bergwelt-Baildon, Jens Ricke, Volker Heinemann, C. Benedikt Westphalen, Wolfgang G. Kunz

Publikováno v: Cancer Imaging, Vol 24, Iss 1, Pp 1-8 (2024)

Abstract Purpose To assess the eligibility of patients with advanced or recurrent solid malignancies presented to a molecular tumor board (MTB) at a large precision oncology center for inclusion in trials with the endpoints objective response rate (O

Externí odkaz: https://doaj.org/article/47042810f04d489eba1c81669198440c

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Akademický článek

The Traumatic Inoculation Process Affects TSPO Radioligand Uptake in Experimental Orthotopic Glioblastoma

Publikováno v: Biomedicines, Vol 12, Iss 1, p 188 (2024)

Background: The translocator protein (TSPO) has been proven to have great potential as a target for the positron emission tomography (PET) imaging of glioblastoma. However, there is an ongoing debate about the potential various sources of the TSPO PE

Externí odkaz: https://doaj.org/article/bab7c24b04b64509ad8004cad24a8c44

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Akademický článek

18 kDa translocator protein positron emission tomography facilitates early and robust tumor detection in the immunocompetent SB28 glioblastoma mouse model

Publikováno v: Frontiers in Medicine, Vol 9 (2022)

IntroductionThe 18 kDa translocator protein (TSPO) receives growing interest as a biomarker in glioblastoma. Mouse models can serve as an important tool for the investigation of biomarkers in glioblastoma, but several glioblastoma models indicated on

Externí odkaz: https://doaj.org/article/3005aeed99994e34b3cb32a36542ee40

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Akademický článek

PSMA PET Imaging in Glioblastoma: A Preclinical Evaluation and Theranostic Outlook

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

BackgroundProstate specific membrane antigen (PSMA) PET imaging has recently gained attention in glioblastoma (GBM) patients as a potential theranostic target for PSMA radioligand therapy. However, PSMA PET has not yet been established in a murine GB

Externí odkaz: https://doaj.org/article/a33fdca79420480f90602dfda9688c64

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Akademický článek

Longitudinal [18F]GE-180 PET Imaging Facilitates In Vivo Monitoring of TSPO Expression in the GL261 Glioblastoma Mouse Model

Autor: Adrien Holzgreve, Dennis Pötter, Matthias Brendel, Michael Orth, Lorraine Weidner, Lukas Gold, Maximilian A. Kirchner, Laura M. Bartos, Lena M. Unterrainer, Marcus Unterrainer, Katja Steiger, Louisa von Baumgarten, Maximilian Niyazi, Claus Belka, Peter Bartenstein, Markus J. Riemenschneider, Kirsten Lauber, Nathalie L. Albert

Publikováno v: Biomedicines, Vol 10, Iss 4, p 738 (2022)

The 18 kDa translocator protein (TSPO) is increasingly recognized as an interesting target for the imaging of glioblastoma (GBM). Here, we investigated TSPO PET imaging and autoradiography in the frequently used GL261 glioblastoma mouse model and aim

Externí odkaz: https://doaj.org/article/65102713372f44b49ddfba0d0bd6a181

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Identification of Activating Mutations in the Transmembrane and Extracellular Domains of EGFR

Autor: Anja Wagner, Edgar Galicia-Andrés, Magdalena Teufl, Lukas Gold, Christian Obinger, Peter Sykacek, Chris Oostenbrink, Michael W. Traxlmayr

Publikováno v: Biochemistry. 61:2049-2062

The epidermal growth factor receptor (EGFR) is frequently mutated in human cancer, most notably non-small-cell lung cancer and glioblastoma. While many frequently occurring EGFR mutations are known to confer constitutive EGFR activation, the situatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a93cf387248b3fac97101a45ec224f
https://doi.org/10.1021/acs.biochem.2c00384

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Interplay between Elastic and Electrochemical Properties during Active Material Transitions and Aging of a Lithium‐Ion Battery

Autor: Simon Feiler, Philip Daubinger, Lukas Gold, Sarah Hartmann, Guinevere A. Giffin

Publikováno v: Batteries & Supercaps. 6

The interplay between the internal mechanical properties and external mechanical conditions of a battery cell, e. g., Young's modulus and thickness change, has a crucial impact on the cell performance and lifetime, and thus, needs to be fully underst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7bcbebfa2a06f7a9a8e4cbc3405096
https://doi.org/10.1002/batt.202200518

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Ultrasound Propagation in Lithium‐Ion Battery Cell Materials: Basis for Developing Monitoring and Imaging Methods

Autor: Lukas Gold, Thomas Herzog, Frank Schubert, Henning Heuer, Guinevere A. Giffin

Publikováno v: Energy Technology. 11

State-of-the-art methods to monitor the degree of wetting of lithium-ion batteries during production, which are applicable at an industrial scale, are not capable of determining the spatial electrolyte distribution in the porous network of electrodes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c2ca9eddafb2f155f7c72d58dd7819
https://doi.org/10.1002/ente.202200861

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