Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lukas Cha"'
Publikováno v:
Frontiers in Robotics and AI, Vol 11 (2024)
In the realm of precision cattle health monitoring, this paper introduces the development and evaluation of a novel wearable continuous health monitoring device designed for cattle. The device integrates a sustainable solar-powered module, real-time
Externí odkaz:
https://doaj.org/article/e372427f471949b5b01cad3926427a53
Autor:
Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin Hübner, Abhijit Chakraborty, Meghana Pagadala, Rosalind Bump, Sahaana Chandran, Katerina Kraft, Rocio Acuna-Hidalgo, Derek Reid, Kristin Sikkink, Monika Mauermann, Edwin F. Juarez, Anne Jenseit, James T. Robinson, Kristian W. Pajtler, Till Milde, Natalie Jäger, Petra Fiesel, Ling Morgan, Sunita Sridhar, Nicole G. Coufal, Michael Levy, Denise Malicki, Charlotte Hobbs, Stephen Kingsmore, Shareef Nahas, Matija Snuderl, John Crawford, Robert J. Wechsler-Reya, Tom Belle Davidson, Jennifer Cotter, George Michaiel, Gudrun Fleischhack, Stefan Mundlos, Anthony Schmitt, Hannah Carter, Kulandaimanuvel Antony Michealraj, Sachin A. Kumar, Michael D. Taylor, Jeremy Rich, Frank Buchholz, Jill P. Mesirov, Stefan M. Pfister, Ferhat Ay, Jesse R. Dixon, Marcel Kool, Lukas Chavez
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Ependymoma is a tumor of the brain or spinal cord. The two most common and aggressive molecular groups of ependymoma are the supratentorial ZFTA-fusion associated and the posterior fossa ependymoma group A. In both groups, tumors occur mainl
Externí odkaz:
https://doaj.org/article/7c75228f7b794031a963791639822393
Autor:
Kristian W. Pajtler, Yiju Wei, Konstantin Okonechnikov, Patricia B. G. Silva, Mikaella Vouri, Lei Zhang, Sebastian Brabetz, Laura Sieber, Melissa Gulley, Monika Mauermann, Tatjana Wedig, Norman Mack, Yuka Imamura Kawasawa, Tanvi Sharma, Marc Zuckermann, Felipe Andreiuolo, Eric Holland, Kendra Maass, Huiqin Körkel-Qu, Hai-Kun Liu, Felix Sahm, David Capper, Jens Bunt, Linda J. Richards, David T. W. Jones, Andrey Korshunov, Lukas Chavez, Peter Lichter, Mikio Hoshino, Stefan M. Pfister, Marcel Kool, Wei Li, Daisuke Kawauchi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The molecular mechanisms driving proliferation in the pediatric brain cancer epdendymoma are poorly understood. Here the authors show that a YAP1- MAMLD1 fusion drives tumor formation in mice and show that the fusion protein can collaborate with the
Externí odkaz:
https://doaj.org/article/adf1b461d84d45cc809ee416ce32b241
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-7 (2019)
Abstract Background High-throughput technologies for analyzing chromosome conformation at a genome scale have revealed that chromatin is organized in topologically associated domains (TADs). While TADs are relatively stable across cell types, intra-T
Externí odkaz:
https://doaj.org/article/60bd32224a234a588850e5f4613b28d7
Autor:
Matija Snuderl, Kasthuri Kannan, Elke Pfaff, Shiyang Wang, James M. Stafford, Jonathan Serrano, Adriana Heguy, Karina Ray, Arline Faustin, Olga Aminova, Igor Dolgalev, Stacie L. Stapleton, David Zagzag, Luis Chiriboga, Sharon L. Gardner, Jeffrey H. Wisoff, John G. Golfinos, David Capper, Volker Hovestadt, Marc K. Rosenblum, Dimitris G. Placantonakis, Sarah E. LeBoeuf, Thales Y. Papagiannakopoulos, Lukas Chavez, Sama Ahsan, Charles G. Eberhart, Stefan M. Pfister, David T. W. Jones, Matthias A. Karajannis
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Pineoblastoma is a highly aggressive and rare childhood brain cancer, and the genetic drivers of sporadic pineoblastoma are unknown. Here, the authors genomically interrogated pediatric and adult pineoblastomas and found novel variants including recu
Externí odkaz:
https://doaj.org/article/ead93584496f48eaacd71d7cac4d1501
Publikováno v:
Electronic Proceedings in Theoretical Computer Science, Vol 233, Iss Proc. MEMICS 2016, Pp 87-93 (2016)
HADES is a fully automated verification tool for pipeline-based microprocessors that aims at flaws caused by improperly handled data hazards. It focuses on single-pipeline microprocessors designed at the register transfer level (RTL) and deals with r
Externí odkaz:
https://doaj.org/article/e11088bcbf0040f5a07e37ab720ad10f
Autor:
Benjamin Joachim Schmiedel, Grégory Seumois, Daniela Samaniego-Castruita, Justin Cayford, Veronique Schulten, Lukas Chavez, Ferhat Ay, Alessandro Sette, Bjoern Peters, Pandurangan Vijayanand
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Variations in the 17q21 locus are linked to asthma susceptibility and other autoimmune diseases. Here, the authors perform cell type-specific functional genomic analyses of asthma-risk SNPs, and show a genotype specific mechanism of differential gene
Externí odkaz:
https://doaj.org/article/e3236bb261ed40f88943e91e159bc89e
Publikováno v:
F1000Research, Vol 7 (2018)
Illumina Infinium DNA methylation arrays are a cost-effective technology to measure DNA methylation at CpG sites genome-wide and across cohorts of normal and cancer samples. While copy number alterations are commonly inferred from array-CGH, SNP arra
Externí odkaz:
https://doaj.org/article/661dc12ad1574abd9b3481a1a2eba89f
Autor:
Christina Grimm, Lukas Chavez, Mireia Vilardell, Alexandra L Farrall, Sascha Tierling, Julia W Böhm, Phillip Grote, Matthias Lienhard, Jörn Dietrich, Bernd Timmermann, Jörn Walter, Michal R Schweiger, Hans Lehrach, Ralf Herwig, Bernhard G Herrmann, Markus Morkel
Publikováno v:
PLoS Genetics, Vol 9, Iss 2, p e1003250 (2013)
Aberrant CpG methylation is a universal epigenetic trait of cancer cell genomes. However, human cancer samples or cell lines preclude the investigation of epigenetic changes occurring early during tumour development. Here, we have used MeDIP-seq to a
Externí odkaz:
https://doaj.org/article/f1689bb6ce554651818e5958827f19fb
Autor:
Anna Gerasimova, Lukas Chavez, Bin Li, Gregory Seumois, Jason Greenbaum, Anjana Rao, Pandurangan Vijayanand, Bjoern Peters
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54359 (2013)
Genome-wide association studies (GWASs) identify single nucleotide polymorphisms (SNPs) that are enriched in individuals suffering from a given disease. Most disease-associated SNPs fall into non-coding regions, so that it is not straightforward to i
Externí odkaz:
https://doaj.org/article/2300a2de719f4f21b15b066e7832dbda