Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lukas Baitsch"'
Autor:
Yubao Wang, Young-Mi Li, Lukas Baitsch, Alan Huang, Yi Xiang, Haoxuan Tong, Ana Lako, Thanh Von, Christine Choi, Elgene Lim, Junxia Min, Li Li, Frank Stegmeier, Robert Schlegel, Michael J Eck, Nathanael S Gray, Timothy J Mitchison, Jean J Zhao
Publikováno v:
eLife, Vol 7 (2018)
Externí odkaz:
https://doaj.org/article/a6b6eeaea2a247debe5c4f96ff9b82c5
Autor:
Yubao Wang, Young-Mi Lee, Lukas Baitsch, Alan Huang, Yi Xiang, Haoxuan Tong, Ana Lako, Thanh Von, Christine Choi, Elgene Lim, Junxia Min, Li Li, Frank Stegmeier, Robert Schlegel, Michael J Eck, Nathanael S Gray, Timothy J Mitchison, Jean J Zhao
Publikováno v:
eLife, Vol 3 (2014)
Despite marked advances in breast cancer therapy, basal-like breast cancer (BBC), an aggressive subtype of breast cancer usually lacking estrogen and progesterone receptors, remains difficult to treat. In this study, we report the identification of M
Externí odkaz:
https://doaj.org/article/98d803d655a846bd8167d9d345c5f996
Autor:
Lukas Baitsch, Amandine Legat, Leticia Barba, Silvia A Fuertes Marraco, Jean-Paul Rivals, Petra Baumgaertner, Céline Christiansen-Jucht, Hanifa Bouzourene, Donata Rimoldi, Hanspeter Pircher, Nathalie Rufer, Maurice Matter, Olivier Michielin, Daniel E Speiser
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30852 (2012)
Inhibitory receptors mediate CD8 T-cell hyporesponsiveness against cancer and infectious diseases. PD-1 and CTLA-4 have been extensively studied, and blocking antibodies have already shown clinical benefit for cancer patients. Only little is known on
Externí odkaz:
https://doaj.org/article/56e9997bcbd74169b36b4ddd91de0ef4
Autor:
Pedro Romero, Daniel E. Speiser, Immanuel F. Luescher, Jean-Marie Tiercy, William W. Kwok, Nathalie Rufer, Sébastien Wieckowski, Lukas Baitsch, Laurent Derré, Danijel Dojcinovic, Gilles Bioley, Camilla Jandus
We have previously shown that vaccination of HLA-A2 metastatic melanoma patients with the analogue Melan-A26-35(A27L) peptide emulsified in a mineral oil induces ex vivo detectable specific CD8 T cells. These are further enhanced when a TLR9 agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eab1d6aa13b5590d2ee7e4235f69ef4
https://doi.org/10.1158/0008-5472.c.6500465
https://doi.org/10.1158/0008-5472.c.6500465
Autor:
Pedro Romero, Daniel E. Speiser, Immanuel F. Luescher, Jean-Marie Tiercy, William W. Kwok, Nathalie Rufer, Sébastien Wieckowski, Lukas Baitsch, Laurent Derré, Danijel Dojcinovic, Gilles Bioley, Camilla Jandus
Supplementary Figure 3 from Tumor Antigen–Specific FOXP3+ CD4 T Cells Identified in Human Metastatic Melanoma: Peptide Vaccination Results in Selective Expansion of Th1-like Counterparts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f0615d49f4b8b52c11dbc910737f84
https://doi.org/10.1158/0008-5472.22383230.v1
https://doi.org/10.1158/0008-5472.22383230.v1
Autor:
Pedro Romero, Daniel E. Speiser, Immanuel F. Luescher, Jean-Marie Tiercy, William W. Kwok, Nathalie Rufer, Sébastien Wieckowski, Lukas Baitsch, Laurent Derré, Danijel Dojcinovic, Gilles Bioley, Camilla Jandus
Supplementary Figure 2 from Tumor Antigen–Specific FOXP3+ CD4 T Cells Identified in Human Metastatic Melanoma: Peptide Vaccination Results in Selective Expansion of Th1-like Counterparts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d472beba34cee39b5ae23d6bc70b625
https://doi.org/10.1158/0008-5472.22383233.v1
https://doi.org/10.1158/0008-5472.22383233.v1
Autor:
Robert Schlegel, Yi Xiang, Timothy J. Mitchison, Yubao Wang, Haoxuan Tong, Thanh Von, Frank Stegmeier, Nathanael S. Gray, Li Li, Ana Lako, Junxia Min, Elgene Lim, Lukas Baitsch, Alan Huang, Jean J. Zhao, Young-Mi Li, Michael J. Eck, Christine Choi
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Despite marked advances in breast cancer therapy, basal-like breast cancer (BBC), an aggressive subtype of breast cancer usually lacking estrogen and progesterone receptors, remains difficult to treat. In this study, we report the identification of M
Autor:
Michael J. Kluk, Shavali Shaik, J. Wade Harper, Alban Ordureau, Anne Fassl, Jon C. Aster, Li Na, Moni Roy, Sarah Jenkinson, Piotr Sicinski, Steven P. Gygi, Clifford A. Meyer, Tobias Otto, Kristin A. Mulry, Wenyi Wei, Alejandro Gutierrez, David C. Linch, Agnieszka Zagozdzon, Bryan King, Harald von Boehmer, Lijun Liu, A. Thomas Look, Jean J. Zhao, Xiaoyu Li, Nan Ke, Yan Geng, Joel M. Chick, Charles G. Mullighan, Hiroyuki Inuzuka, Taras Kreslavsky, Lukas Baitsch, Rosemary E. Gale, Sunkyu Kim, Xiaowu Zhang, Iannis Aifantis, Marc R. Mansour, Leah Bury, Haizhen Wang
Publikováno v:
Nature Cell Biology. 16:1080-1091
Cyclin C was cloned as a growth-promoting G1 cyclin, and was also shown to regulate gene transcription. Here we report that in vivo cyclin C acts as a haploinsufficient tumour suppressor, by controlling Notch1 oncogene levels. Cyclin C activates an '
Autor:
Danilo Presotto, Olivier Michielin, Nathalie Rufer, Lukas Baitsch, Daniel E. Speiser, Petra Baumgaertner, Michael Hebeisen, Pedro Romero
Publikováno v:
Journal of Clinical Investigation, vol. 123, no. 3, pp. 1044-1056
J Clin Invest
The Journal of clinical investigation
J Clin Invest
The Journal of clinical investigation
Anti-self/tumor T cell function can be improved by increasing TCR-peptide MHC (pMHC) affinity within physiological limits, but paradoxically further increases (K(d) < 1 μM) lead to drastic functional declines. Using human CD8(+) T cells engineered w
Autor:
Daniel E. Speiser, Leticia Barba, Amandine Legat, Lukas Baitsch, Nathalie Rufer, Hanifa Bouzourene, Sunil K. Raghav, Petra Baumgaertner, Pedro Romero, Bart Deplancke, Sébastien Wieckowski, Estelle Devevre
Publikováno v:
Journal of Clinical Investigation, vol. 121, no. 6, pp. 2350-2360
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (6), pp.2350-2360. ⟨10.1172/JCI46102⟩
The Journal of clinical investigation
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2011, 121 (6), pp.2350-2360. ⟨10.1172/JCI46102⟩
The Journal of clinical investigation
International audience; In chronic viral infections, CD8⁺ T cells become functionally deficient and display multiple molecular alterations. In contrast, only little is known of self- and tumor-specific CD8⁺ T cells from mice and humans. Here we d