Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lukas B Tanner"'
Autor:
Frederic Vigant, Jihye Lee, Axel Hollmann, Lukas B Tanner, Zeynep Akyol Ataman, Tatyana Yun, Guanghou Shui, Hector C Aguilar, Dong Zhang, David Meriwether, Gleyder Roman-Sosa, Lindsey R Robinson, Terry L Juelich, Hubert Buczkowski, Sunwen Chou, Miguel A R B Castanho, Mike C Wolf, Jennifer K Smith, Ashley Banyard, Margaret Kielian, Srinivasa Reddy, Markus R Wenk, Matthias Selke, Nuno C Santos, Alexander N Freiberg, Michael E Jung, Benhur Lee
Publikováno v:
PLoS Pathogens, Vol 9, Iss 4, p e1003297 (2013)
LJ001 is a lipophilic thiazolidine derivative that inhibits the entry of numerous enveloped viruses at non-cytotoxic concentrations (IC50 ≤ 0.5 µM), and was posited to exploit the physiological difference between static viral membranes and biogeni
Externí odkaz:
https://doaj.org/article/5782a66da0c04ff5a689050288b55985
Autor:
Stanislav Y. Shvartsman, Joshua D. Rabinowitz, Yatsuhisa Nagano, Lukas B. Tanner, Yonghyun Song, Junyoung O. Park
Publikováno v:
Current biology : CB, vol 29, iss 12
Curr Biol
Curr Biol
Eggs of oviparous animals must be prepared to develop rapidly and robustly until hatching. The balance between sugars, fats, and other macromolecules must therefore be carefully considered when loading the egg with nutrients. Clearly, packing too muc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e07455a75692c70f0f9d3bd6f7c238c5
https://escholarship.org/uc/item/9zv0g71g
https://escholarship.org/uc/item/9zv0g71g
Autor:
Tyler B. Jacobson, Sophia Hsin-Jung Li, Joshua D. Rabinowitz, Zheyun Zhang, Sara A. Rubin, Meytal B. Higgins, Monica H. Wei, Junyoung O. Park, David M. Stevenson, Daniel Amador-Noguez, Lukas B. Tanner, Daven B. Khana
Publikováno v:
Nat Chem Biol
Glycolysis plays a central role in producing ATP and biomass. Its control principles, however, remain incompletely understood. Here, we develop a method that combines (2)H and (13)C tracers to determine glycolytic thermodynamics. Using this method, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5386aca8073a69735f7073282ae892f4
https://pubmed.ncbi.nlm.nih.gov/31548693
https://pubmed.ncbi.nlm.nih.gov/31548693
Autor:
Eng Eong Ooi, Yee Sin Leo, Mark Schreiber, Jenny G. Low, Lukas B. Tanner, Yee-Ling Lai, Subhash G. Vasudevan, Lee Ching Ng, Cameron P. Simmons, Adrian Ong, Le Thi Puong, Martin L. Hibberd, Thomas Tolfvenstam
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 2, Iss 3, p e196 (2008)
PLoS Neglected Tropical Diseases, Vol 2, Iss 3, p e196 (2008)
Background Dengue is re-emerging throughout the tropical world, causing frequent recurrent epidemics. The initial clinical manifestation of dengue often is confused with other febrile states confounding both clinical management and disease surveillan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed26c327bfd1d5e984bdb80a1c43892
https://doi.org/10.1371/journal.pntd.0000196
https://doi.org/10.1371/journal.pntd.0000196
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 7, Pp 1357-1365 (2014)
Influenza virus acquires a host-derived lipid envelope during budding, yet a convergent view on the role of host lipid metabolism during infection is lacking. Using a mass spectrometry-based lipidomics approach, we provide a systems-scale perspective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cd5cb0a2673cfc670cdb2f9b03177e
http://www.sciencedirect.com/science/article/pii/S0022227520352421
http://www.sciencedirect.com/science/article/pii/S0022227520352421
Autor:
Lukas B. Tanner, Travis L. Rodkey, Robert G. Parton, Yong Zhou, Nicholas Ariotti, Michelle M. Hill, John F. Hancock, Kerry L. Inder, Markus R. Wenk, Manuel A. Fernandez-Rojo
Publikováno v:
The Journal of Cell Biology
Caveolae transduce mechanical stress into plasma membrane lipid alterations that disrupt Ras organization in an isoform-specific manner and modulate downstream signal transduction.
The molecular mechanisms whereby caveolae exert control over cel
The molecular mechanisms whereby caveolae exert control over cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9dd380a925c390d093e65e308cdbab
https://doi.org/10.1083/jcb.201307055
https://doi.org/10.1083/jcb.201307055
Autor:
Sang Yoon Lee, Guanghou Shui, Pietro De Camilli, Lukas B. Tanner, Fubito Nakatsu, Jeremy M. Baskin, Mingming Hao, Markus R. Wenk, Jeeyun Chung, Nicholas T. Ingolia, Michelle Pirruccello
Publikováno v:
The Journal of Cell Biology, vol 199, iss 6
The Journal of cell biology, vol 199, iss 6
The Journal of Cell Biology
The Journal of cell biology, vol 199, iss 6
The Journal of Cell Biology
PI4KIIIα is targeted to the plasma membrane via an evolutionarily conserved complex comprised of EFR3 and TTC7 to control PtdIns4P synthesis and the selective enrichment of PtdIns(4,5)P2 in this membrane.
Plasma membrane phosphatidylinositol (P
Plasma membrane phosphatidylinositol (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b599c3d6f9979a2b9c1cdb76d819d3
https://doi.org/10.1083/jcb.201206095
https://doi.org/10.1083/jcb.201206095
Autor:
Lukas B. Tanner, Xue Li Guan, Sumarlin Lee, Petra Kukkaro, Yin Hoe Yau, Susana Geifman Shochat, Pei Yong Shi, Vernon Seow, Markus R. Wenk, Guntur Fibriansah, Shee-Mei Lok, Qian Zhang, Goran Biuković, Cornelia Hunke, Pau Ling Chew, Gerhard Grüber
Publikováno v:
Journal of Biological Chemistry. 287:40525-40534
Dengue virus surface proteins, envelope (E) and pre-membrane (prM), undergo rearrangement during the maturation process at acidic condition.prM-stem region binds tighter to both E protein and lipid membrane when environment becomes acidic.At acidic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e412600992f6c587ee001806f9c9ec71
https://doi.org/10.1074/jbc.m112.384446
https://doi.org/10.1074/jbc.m112.384446
Autor:
Lukas B. Tanner, Junyoung O. Park, Talen Sehgal, Monica H. Wei, Jared E. Toettcher, Lance Parsons, Eileen White, Joshua D. Rabinowitz, Alexander G. Goglia
Publikováno v:
Cell Systems. 7:49-62.e8
Summary Altered glycolysis is a hallmark of diseases including diabetes and cancer. Despite intensive study of the contributions of individual glycolytic enzymes, systems-level analyses of flux control through glycolysis remain limited. Here, we over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839a389823edda107449e0070d74750a
https://doi.org/10.1016/j.cels.2018.06.003
https://doi.org/10.1016/j.cels.2018.06.003
Publikováno v:
Chemistry and Physics of Lipids
Enveloped viruses, which include many medically important viruses such as human immunodeficiency virus, influenza virus and hepatitis C virus, are intracellular parasites that acquire lipid envelopes from their host cells. Success of replication is i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::343e3bbaf1e29394e3bae90c80136003
https://doi.org/10.1016/j.chemphyslip.2010.03.002
https://doi.org/10.1016/j.chemphyslip.2010.03.002