Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lukas, Tombor"'
Autor:
Timothy Warwick, Giulia Karolin Buchmann, Beatrice Pflüger-Müller, Manuela Spaeth, Christoph Schürmann, Wesley Abplanalp, Lukas Tombor, David John, Andreas Weigert, Martin Leo-Hansmann, Stefanie Dimmeler, Ralf P. Brandes
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Treatment of vascular stenosis with angioplasty results in acute vascular damage, which may lead to restenosis. Owing to the highly complex cellularity of blood vessels, the healing response following this damage is incompletely understood. To gain f
Externí odkaz:
https://doaj.org/article/454a1536af07482ea7ac4e54de55b5f6
Autor:
Giulia K. Buchmann, Christoph Schürmann, Manuela Spaeth, Wesley Abplanalp, Lukas Tombor, David John, Timothy Warwick, Flávia Rezende, Andreas Weigert, Ajay M. Shah, Martin-Leo Hansmann, Norbert Weissmann, Stefanie Dimmeler, Katrin Schröder, Ralf P. Brandes
Publikováno v:
Redox Biology, Vol 45, Iss , Pp 102050- (2021)
Objective: The NADPH oxidase Nox4 is an important source of H2O2. Nox4-derived H2O2 limits vascular inflammation and promotes smooth muscle differentiation. On this basis, the role of Nox4 for restenosis development was determined in the mouse caroti
Externí odkaz:
https://doaj.org/article/1f3244d203f94483865ef6a1ec58116c
Autor:
Jörg-Detlef Drenckhahn, Luka Nicin, Sara Akhouaji, Svenja Krück, Anna Eva Blank, Anne Schänzer, Uygar Yörüker, Christian Jux, Lukas Tombor, Wesley Abplanalp, David John, Andreas M. Zeiher, Stefanie Dimmeler, Stefan Rupp
Publikováno v:
Journal of Molecular and Cellular Cardiology. 178:22-35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71ef09df01805a107dbddf09ee9e0ae8
https://doi.org/10.1016/j.yjmcc.2023.03.003
https://doi.org/10.1016/j.yjmcc.2023.03.003
Autor:
Luka Nicin, Sam Michael Schroeter, Simone Franziska Glaser, Ralf Schulze-Brüning, Minh-Duc Pham, Susanne S. Hille, Michail Yekelchyk, Badder Kattih, Wesley Tyler Abplanalp, Lukas Tombor, Oliver J. Müller, Thomas Braun, Benjamin Meder, Christoph Reich, Mani Arsalan, Tomas Holubec, Thomas Walther, Fabian Emrich, Jaya Krishnan, Andreas M. Zeiher, David John, Stefanie Dimmeler
Publikováno v:
Nature Cardiovascular Research. 1:174-185
Pathological cardiac hypertrophy is a leading cause of heart failure, but knowledge of the full repertoire of cardiac cells and their gene expression profiles in the human hypertrophic heart is missing. Here, by using large-scale single-nucleus trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::981aa3bc630c6211853e8aa27779fb04
https://doi.org/10.1038/s44161-022-00019-7
https://doi.org/10.1038/s44161-022-00019-7
Autor:
Julian U. G. Wagner, Lukas Tombor, Pedro Felipe Malacarne, Lisa-Maria Kettenhausen, Josefine Panthel, Maria Cipca, Kathrin A. Stilz, Ariane Fischer, Marion Muhly-Reinholz, Wesley T. Abplanalp, David John, Giulia K. Buchmann, Stephan Angendohr, Ehsan Amin, Katharina Scherschel, Nikolaj Klöcker, Malte Kelm, Dominik Schüttler, Sebastian Clauss, Stefan Guenther, Thomas Boettger, Thomas Braun, Christian Bär, Eleonora Nardini, Selma Osmanagic-Myers, Christian Meyer, Andreas M. Zeiher, Ralf P. Brandes, Guillermo Luxán, Stefanie Dimmeler
Aging is a major risk factor for impaired cardiovascular health. The aging myocardium is characterized by electrophysiological dysfunctions such as a reduced heart rate variability. These alterations can be intrinsic within cardiomyocytes, but might
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c37a05188cdbda288f09c07dba5011bf
https://doi.org/10.1101/2022.07.29.501999
https://doi.org/10.1101/2022.07.29.501999
Autor:
Mario Looso, Stefan Offermanns, Lukas Tombor, Voahanginirina Randriamboavonjy, Philipp Goymann, Anastasia Kyselova, Stephen L. Nishimura, Stefanie Dimmeler, Alberto Fernando Oliveira Justo, Matthias S. Leisegang, Sven Zukunft, Andreas Weigert, Andreas Papapetropoulos, Beate Fisslthaler, Sofia-Iris Bibli, Juliana Heidler, Janina Wittig, Ingrid Fleming, Corina Ratiu, Jiong Hu, Fragiska Sigala, Diamantis I. Tsilimigras, Stefan Knapp, Fredy Delgado Lagos, Ralf P. Brandes, Ilka Wittig, Maria Kyriaki Drekolia
Publikováno v:
Circulation. 143:935-948
Background: In vascular endothelial cells, cysteine metabolism by the cystathionine γ lyase (CSE), generates hydrogen sulfide–related sulfane sulfur compounds (H 2 S n ), that exert their biological actions via cysteine S -sulfhydration of target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45fbc368eaf9af958ab0a083e4851697
https://doi.org/10.1161/circulationaha.120.051877
https://doi.org/10.1161/circulationaha.120.051877
Autor:
Norbert Weissmann, Andreas Weigert, Ralf P. Brandes, David John, Flávia Rezende, Timothy Warwick, Wesley Abplanalp, Ajay M. Shah, Stefanie Dimmeler, Martin-Leo Hansmann, Manuela Spaeth, Katrin Schröder, Giulia K. Buchmann, Christoph Schürmann, Lukas Tombor
Publikováno v:
Redox Biology, Vol 45, Iss, Pp 102050-(2021)
Redox Biology
Redox Biology
Objective The NADPH oxidase Nox4 is an important source of H2O2. Nox4-derived H2O2 limits vascular inflammation and promotes smooth muscle differentiation. On this basis, the role of Nox4 for restenosis development was determined in the mouse carotid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e703414872b10b641c389d4243a1ed58
http://www.sciencedirect.com/science/article/pii/S2213231721002093
http://www.sciencedirect.com/science/article/pii/S2213231721002093
Publikováno v:
GigaScience. 11
Background With the rise of single-cell RNA sequencing new bioinformatic tools have been developed to handle specific demands, such as quantifying unique molecular identifiers and correcting cell barcodes. Here, we benchmarked several datasets with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99c08169fcbe7934eb62ecedd5396e7
https://pubmed.ncbi.nlm.nih.gov/35084033
https://pubmed.ncbi.nlm.nih.gov/35084033
Autor:
Hakan Akintuerk, Matthias Keuper, Hannah Mellentin, Evelyn Ullrich, Reinhard Dettmeyer, David John, Christian Jux, Anne Schänzer, Andreas M. Zeiher, Luka Nicin, Karin Klingel, A. Sprengel, Dietmar Schranz, Stefan Rupp, Wesley Abplanalp, Stefanie Dimmeler, Jedrzej Hoffmann, Lukas Tombor
Publikováno v:
Circulation. 143(17)
Background: Dilated cardiomyopathy (DCM) is a leading cause of death in children with heart failure. The outcome of pediatric heart failure treatment is inconsistent, and large cohort studies are lacking. Progress may be achieved through personalized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f3c0c965dc0efcc1817b67cd23e801
https://pubmed.ncbi.nlm.nih.gov/33618539
https://pubmed.ncbi.nlm.nih.gov/33618539
With the rise of single cell RNA sequencing new bioinformatic tools became available to handle specific demands, such as quantifying unique molecular identifiers and correcting cell barcodes. Here, we analysed several datasets with the most common al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b04c89230f86bcecac8e7438a773fdc
https://doi.org/10.1101/2021.02.15.430948
https://doi.org/10.1101/2021.02.15.430948