Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Lukas, Nalos"'
Autor:
Vaclav Tegl, Jan Horak, Lukas Nalos, Michala Horakova, Milan Stengl, Martin Matejovic, Jan Benes
Publikováno v:
Intensive Care Medicine Experimental, Vol 12, Iss 1, Pp 1-11 (2024)
Abstract Objectives The use of hemoadsorption (HA) has become popular in the treatment of vasoplegic states associated with massive cytokine release, including septic shock. However, this approach does not seem to be based on robust evidence, and it
Externí odkaz:
https://doaj.org/article/2c3d9c4cd7f141d59b9b3520bb67950e
Autor:
Miroslava Chalupova, Jan Horak, Lenka Kramna, Lukas Nalos, Milan Stengl, Katerina Chudejova, Lucie Kraftova, Ondrej Cinek, Pavel Klein, Martin Matejovic, Jaroslav Hrabak
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-6 (2022)
Abstract Animal models are essential in understanding of the mechanisms of sepsis moreover the development and the assessment of emerging therapies. In clinically relevant porcine model, however, a significant variability in the host response has bee
Externí odkaz:
https://doaj.org/article/08f8a520f3da4b1f8fc15b05bbbde0ed
Autor:
Jan Horak, Lukas Nalos, Vendula Martinkova, Vaclav Tegl, Lucie Vistejnova, Jitka Kuncova, Michaela Kohoutova, Dagmar Jarkovska, Martina Dolejsova, Jan Benes, Milan Stengl, Martin Matejovic
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background: Treatment with mesenchymal stem cells (MSCs) has elicited considerable interest as an adjunctive therapy in sepsis. However, the encouraging effects of experiments with MSC in rodents have not been adequately studied in large-animal model
Externí odkaz:
https://doaj.org/article/20a0836abf8d4d94aa34c6545fa7c494
Autor:
Dagmar Jarkovska, Michaela Markova, Jan Horak, Lukas Nalos, Jan Benes, Mahmoud Al-Obeidallah, Zdenek Tuma, Jitka Sviglerova, Jitka Kuncova, Martin Matejovic, Milan Stengl
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
The complex pathogenesis of sepsis and septic shock involves myocardial depression, the pathophysiology of which, however, remains unclear. In this study, cellular mechanisms of myocardial depression were addressed in a clinically relevant, large ani
Externí odkaz:
https://doaj.org/article/a0a12b161eb2499fab8ccf8e48c039fe
Publikováno v:
Anesteziologie a intenzivní medicína. 31:172-175
V poslednich letech přitahuje terapeutický přistup s využitim mimotělnich hemadsorpcnich metod u kriticky nemocných stale větsi zajem. Snaha o casný zasah do patofyziologických procesů, ktere doprovazeji řadu inzultů u pacientů v intenzi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9846c6c87d26ee25b14d62199477fd6
https://doi.org/10.36290/aim.2020.035
https://doi.org/10.36290/aim.2020.035
Autor:
Jan, Horak, Lukas, Nalos, Vendula, Martinkova, Vaclav, Tegl, Lucie, Vistejnova, Jitka, Kuncova, Michaela, Kohoutova, Dagmar, Jarkovska, Martina, Dolejsova, Jan, Benes, Milan, Stengl, Martin, Matejovic
Publikováno v:
Frontiers in Immunology
Background: Treatment with mesenchymal stem cells (MSCs) has elicited considerable interest as an adjunctive therapy in sepsis. However, the encouraging effects of experiments with MSC in rodents have not been adequately studied in large-animal model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e1d84303ec55470399bf0e5f9f3db6c
https://pubmed.ncbi.nlm.nih.gov/32117276
https://pubmed.ncbi.nlm.nih.gov/32117276
Publikováno v:
Journal of pharmacological and toxicological methods. 98
The pig is one of the most valuable in vivo models in biomedical research, however with only a few well-accessible veins suitable for venipuncture. Moreover, most of the known methods of blood collection are suitable only for a limited time period. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4d753162dd762344d8f5dd76c1ee898
https://pubmed.ncbi.nlm.nih.gov/31100450
https://pubmed.ncbi.nlm.nih.gov/31100450
Autor:
Michaela, Kohoutova, Jan, Horak, Dagmar, Jarkovska, Vendula, Martinkova, Vaclav, Tegl, Lukas, Nalos, Lucie, Vistejnova, Jan, Benes, Jitka, Sviglerova, Jitka, Kuncova, Martin, Matejovic, Milan, Stengl
Publikováno v:
Critical care medicine. 47(6)
To investigate the potential benefits of vagus nerve stimulation in a clinically-relevant large animal model of progressive sepsis.Prospective, controlled, randomized trial.University animal research laboratory.Twenty-five domestic pigs were divided
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f5d4ce8371d204f5499fbbd915d6bc8
https://pubmed.ncbi.nlm.nih.gov/30908312
https://pubmed.ncbi.nlm.nih.gov/30908312
Autor:
Lukas Nalos, Jan Benes, Vojech Danihel, Vendula Martinkova, Lenka Valesova, Jiri Chvojka, Martin Matejovic
Publikováno v:
Shock (Augusta, Ga.). 53(1)
As controversy persists regarding the benefits of mechanical circulatory support in septic shock with a predominantly vasoplegic phenotype, preclinical studies may provide a useful alternative to fill the actual knowledge gap. Here, we investigated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47df5692cc46007ca89f8e6cb2953f5c
https://pubmed.ncbi.nlm.nih.gov/30807527
https://pubmed.ncbi.nlm.nih.gov/30807527
Autor:
Dagmar, Jarkovska, Michaela, Markova, Jan, Horak, Lukas, Nalos, Jan, Benes, Mahmoud, Al-Obeidallah, Zdenek, Tuma, Jitka, Sviglerova, Jitka, Kuncova, Martin, Matejovic, Milan, Stengl
Publikováno v:
Frontiers in Physiology
The complex pathogenesis of sepsis and septic shock involves myocardial depression, the pathophysiology of which, however, remains unclear. In this study, cellular mechanisms of myocardial depression were addressed in a clinically relevant, large ani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3668e79a28692e4ce9dc4987f7ee49c8
https://pubmed.ncbi.nlm.nih.gov/29946267
https://pubmed.ncbi.nlm.nih.gov/29946267