Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Lukas, Mach"'
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Plant proteases are essential enzymes that play key roles during crucial phases of plant life. Some proteases are mainly involved in general protein turnover and recycle amino acids for protein synthesis. Other proteases are involved in cell signalli
Externí odkaz:
https://doaj.org/article/dde01dc54fb64494b43a3533bc184082
Autor:
Daniel Hammersley, MD, Abbasin Zegard, MD, Emmanuel Androulakis, MD, Richard Jones, MD, PhD, Osita Okafor, MD, Suzan Hatipoglu, MD, Lukas Mach, MD, Amrit Lota, MD, PhD, Zohya Khalique, MD, PhD, Antonio De Marvao, MD, PhD, Resham Baruah, MD, PhD, Kaushik Guha, James Ware, PhD, Upasana Tayal, MD, PhD, Dudley Pennell, MD, FSCMR, Brian Halliday, MD, PhD, BSc, Tian Qiu, Sanjay Prasad, MD, PhD, Francisco Leyva, MD, PhD
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss , Pp 100353- (2024)
Externí odkaz:
https://doaj.org/article/795b5b5fcf294715bb7ec9fe9b895462
Single cell RNA sequencing sheds light on infiltrating T cells in idiopathic inflammatory myopathies
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)
Idiopathic inflammatory myopathies (IIM), also referred to as “myositis,” are a group of heterogeneous autoimmune disorders characterised by muscle weakness, atrophy and progressive reduced mobility (Lundberg et al, 2021). IIM represent a signifi
Externí odkaz:
https://doaj.org/article/748affd23d794d718d9224b128155ac2
Autor:
Rong Zhu, Daniel Canena, Mateusz Sikora, Miriam Klausberger, Hannah Seferovic, Ahmad Reza Mehdipour, Lisa Hain, Elisabeth Laurent, Vanessa Monteil, Gerald Wirnsberger, Ralph Wieneke, Robert Tampé, Nikolaus F. Kienzl, Lukas Mach, Ali Mirazimi, Yoo Jin Oh, Josef M. Penninger, Gerhard Hummer, Peter Hinterdorfer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Combining high-speed AFM, single molecule recognition force spectroscopy, and molecular dynamics simulations Zhu, Canena, Sikora et al. characterize the interaction dynamics of the trimeric spike protein of SARS-CoV-2 wt, and delta and omicron varian
Externí odkaz:
https://doaj.org/article/4f03cce8155a4e8b9132fcede13abbbb
Autor:
Shiva Izadi, Ulrike Vavra, Stanislav Melnik, Clemens Grünwald-Gruber, Esther Föderl-Höbenreich, Markus Sack, Kurt Zatloukal, Josef Glössl, Eva Stöger, Lukas Mach, Alexandra Castilho, Richard Strasser
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
SARS-CoV-2 infects human cells via binding of the viral spike glycoprotein to its main cellular receptor, angiotensin-converting enzyme 2 (ACE2). The spike protein-ACE2 receptor interaction is therefore a major target for the development of therapeut
Externí odkaz:
https://doaj.org/article/b00aae2617684bc2bb46c3d926f815b9
Autor:
Hassan A. Zaidi, Richard E. Jones, Daniel J. Hammersley, Suzan Hatipoglu, Gabriel Balaban, Lukas Mach, Brian P. Halliday, Pablo Lamata, Sanjay K. Prasad, Martin J. Bishop
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundMachine learning analysis of complex myocardial scar patterns affords the potential to enhance risk prediction of life-threatening arrhythmia in stable coronary artery disease (CAD).ObjectiveTo assess the utility of computational image anal
Externí odkaz:
https://doaj.org/article/df87b301f63c4399b3cc9e06b3774775
Autor:
Advaita Acarya Singh, Priyen Pillay, Previn Naicker, Kabamba Alexandre, Kanyane Malatji, Lukas Mach, Herta Steinkellner, Juan Vorster, Rachel Chikwamba, Tsepo L. Tsekoa
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
The hypersensitive response is elicited by Agrobacterium infiltration of Nicotiana benthamiana, including the induction and accumulation of pathogenesis-related proteins, such as proteases. This includes the induction of the expression of several cys
Externí odkaz:
https://doaj.org/article/cfd344e9e899400299b598eb5312238e
Autor:
Abbas Dehghan, Ioanna Tzoulaki, Antonis Pantazis, Sanjay K Prasad, Lukas Mach, James S Ware, Upasana Tayal, Rachel J Buchan, Angharad M Roberts, A John Baksi, Brian P Halliday, Daniel J Hammersley, Amrit S Lota, Richard E Jones, Devendra Meena
Publikováno v:
Open Heart, Vol 9, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/662e3918ea19417f88ae055b56cf1c06
Autor:
Rong Zhu, Daniel Canena, Mateusz Sikora, Miriam Klausberger, Hannah Seferovic, Ahmad Reza Mehdipour, Lisa Hain, Elisabeth Laurent, Vanessa Monteil, Gerald Wirnsberger, Ralph Wieneke, Robert Tampé, Nikolaus F. Kienzl, Lukas Mach, Ali Mirazimi, Yoo Jin Oh, Josef M. Penninger, Gerhard Hummer, Peter Hinterdorfer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/c26dfffaabb146829cede0f13bbf01ee
Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor
Autor:
Tümay Capraz, Nikolaus F Kienzl, Elisabeth Laurent, Jan W Perthold, Esther Föderl-Höbenreich, Clemens Grünwald-Gruber, Daniel Maresch, Vanessa Monteil, Janine Niederhöfer, Gerald Wirnsberger, Ali Mirazimi, Kurt Zatloukal, Lukas Mach, Josef M Penninger, Chris Oostenbrink, Johannes Stadlmann
Publikováno v:
eLife, Vol 10 (2021)
Infection and viral entry of SARS-CoV-2 crucially depends on the binding of its Spike protein to angiotensin converting enzyme 2 (ACE2) presented on host cells. Glycosylation of both proteins is critical for this interaction. Recombinant soluble huma
Externí odkaz:
https://doaj.org/article/dbd89a04e5aa482e90ecfe601f9c8ab1