Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Lukana Ngiwsara"'
Autor:
Jaggaiah N. Gorantla, Santhi Maniganda, Salila Pengthaisong, Lukana Ngiwsara, Phannee Sawangareetrakul, Suwadee Chokchaisiri, Prasat Kittakoop, Jisnuson Svasti, James R. Ketudat Cairns
Publikováno v:
ACS Omega, Vol 6, Iss 39, Pp 25710-25719 (2021)
Externí odkaz:
https://doaj.org/article/61be673e8e284028b4a8bd08e6b60a00
Autor:
Lukana Ngiwsara, Duangrurdee Wattanasirichaigoon, Thipwimol Tim-Aroon, Kitiwan Rojnueangnit, Saisuda Noojaroen, Arthaporn Khongkraparn, Phannee Sawangareetrakul, James R. Ketudat-Cairns, Ratana Charoenwattanasatien, Voraratt Champattanachai, Chulaluck Kuptanon, Suthipong Pangkanon, Jisnuson Svasti
Publikováno v:
BMC Medical Genetics, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background Pompe disease is a lysosomal storage disorder caused by the deficiency of acid alpha-glucosidase (EC. 3.2.1.20) due to mutations in human GAA gene. The objective of the present study was to examine clinical and molecular character
Externí odkaz:
https://doaj.org/article/20abc3ca858c4e58874ef006f623ebd5
Autor:
Peeranat Jatooratthawichot, Chutima Talabnin, Lukana Ngiwsara, Yepy Hardi Rustam, Jisnuson Svasti, Gavin E. Reid, James R. Ketudat Cairns
Publikováno v:
Metabolites, Vol 10, Iss 12, p 488 (2020)
Glucosylceramide (GlcCer) is a major membrane lipid and the precursor of gangliosides. GlcCer is mainly degraded by two enzymes, lysosomal acid β-glucosidase (GBA) and nonlysosomal β-glucosidase (GBA2), which may have different isoforms because of
Externí odkaz:
https://doaj.org/article/e1e49476268b435db538c526598d267e
Autor:
Siriporn Keeratichamroen, Thiwaree Sornprachum, Lukana Ngiwsara, Narittira Ornnork, Jisnuson Svasti
Publikováno v:
Oncology Reports. 49
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::782339a5ea3e587e1eb0ddd008110b7d
https://doi.org/10.3892/or.2023.8508
https://doi.org/10.3892/or.2023.8508
Autor:
Usanarat Anurathapan, Thipwimol Tim‐Aroon, Wujuan Zhang, Watinee Sanpote, Siranee Wongrungsri, Nitcha Khunin, Somchai Chutipongtanate, Vilawan Chirdkiatgumchai, Lukana Ngiwsara, Suphaneewan Jaovisidha, Arthaporn Khongkraparn, Samart Pakakasama, Jisnuson Svasti, Kenneth D. R. Setchell, Duangrurdee Wattanasirichaigoon, Suradej Hongeng
Publikováno v:
Pediatric Blood & Cancer. 70
Gaucher disease (GD) is a lysosomal storage disorder, characterized by hepatosplenomegaly, pancytopenia, bone diseases, with or without neurological symptoms. Plasma glucosylsphingosine (lyso-Gb1), a highly sensitive and specific biomarker for GD, ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682719432c5051d26fb4454630f388bb
https://doi.org/10.1002/pbc.30149
https://doi.org/10.1002/pbc.30149
Autor:
Suwadee Chokchaisiri, Jaggaiah N. Gorantla, Santhi Maniganda, Lukana Ngiwsara, Jisnuson Svasti, Phannee Sawangareetrakul, S. Pengthaisong, James R. Ketudat Cairns, Prasat Kittakoop
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 39, Pp 25710-25719 (2021)
ACS Omega, Vol 6, Iss 39, Pp 25710-25719 (2021)
α-Glucosyl triazoles have rarely been tested as α-glucosidase inhibitors, partly due to inefficient synthesis of their precursor α-d-glucosylazide (αGA1). Glycosynthase enzymes, made by nucleophile mutations of retaining β-glucosidases, produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46a863d271d41de21dd25a9c865eb02
https://doi.org/10.1021/acsomega.1c03928
https://doi.org/10.1021/acsomega.1c03928
Autor:
Lukana Ngiwsara, Phannee Sawangareetrakul, Duangrurdee Wattanasirichaigoon, Thipwimol Tim-Aroon, Prapai Dejkhamron, Voraratt Champattanachai, James R. Ketudat-Cairns, Jisnuson Svasti
Publikováno v:
Biochemical and biophysical research communications. 636(Pt 1)
Mucopolysaccharidosis type I Hurler syndrome (MPS IH) is a severe lysosomal storage disorder caused by alpha-l-iduronidase (IDUA) deficiency. Premature truncation mutations (PTC) are the most common (50%-70%) type of IDUA mutations and correlate with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce381bdca79f230fcd82ba2c78393ffc
https://pubmed.ncbi.nlm.nih.gov/36332477
https://pubmed.ncbi.nlm.nih.gov/36332477
Autor:
Chantragan Srisomsap, Pisanu Ratanarak, Voraratt Champattanachai, Phannee Sawangareetrakul, Boonchai Boonyawat, Lukana Ngiwsara, Nithiwat Vatanavicharn, James R. Ketudat-Cairns, Jisnuson Svasti, Somporn Liammongkolkul, Pornswan Wasant
Publikováno v:
Molecular Biology Reports. 48:2063-2070
Phenylketonuria (PKU) is an autosomal recessive amino acid metabolism disorder caused by variants in the gene encoding phenylalanine hydroxylase (PAH; EC1.14.16.1). This study aimed to assess the specific heterogeneity of PAH variants found in Thai p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a02ba14e723a47f8e2e2767eae2068e
https://doi.org/10.1007/s11033-021-06163-w
https://doi.org/10.1007/s11033-021-06163-w
Autor:
Pongtai Chaiputtanapun, Kriengsak Lirdprapamongkol, Bongkotrat Thanaussavadate, Thanyaporn Phongphankhum, Thanawit Thippong, Poomsith Thangsan, Phreeranat Montatip, Lukana Ngiwsara, Jisnuson Svasti, Pitak Chuawong
Publikováno v:
ChemMedChem. 17(14)
A collection of 2,3-arylpyridylindole derivatives were synthesized via the Larock heteroannulation and evaluated for their in vitro cytotoxic activity against A549 human lung cancer cells. Two derivatives expressed good cytotoxicity with IC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3afc0effbd5836960ffccc7079db2e6
https://pubmed.ncbi.nlm.nih.gov/35595678
https://pubmed.ncbi.nlm.nih.gov/35595678
Autor:
Charnsak Thongsornkleeb, Pavitra Laohapaisan, Nantamon Supantanapong, Lukana Ngiwsara, Nisachon Khunnawutmanotham, Warabhorn Rodphon, Jumreang Tummatorn, Kriengsak Lirdprapamongkol, Jisnuson Svasti, Onrapak Reamtong, Somsak Ruchirawat
Publikováno v:
ChemMedChem. 16(24)
Eighteen hybrid compounds between 8-bromo-2-fluoro-isocryptolepine (4) and 1,2,3-triazole were synthesized via azide rearrangement-annulation reaction. Compound 4 underwent regioselective N-propargylation and click reaction to form 8-bromo-2-fluoro-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7603100bed710e9390916393b79ec9
https://pubmed.ncbi.nlm.nih.gov/34610210
https://pubmed.ncbi.nlm.nih.gov/34610210