Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Luk Chong Yeung"'
Publikováno v:
Neurocomputing. :437-440
The sign and magnitude of bi-directional synaptic plasticity have been shown to depend on: the rate of presynaptic stimulation, the level of postsynaptic depolarization, and the precise relative timing between pre- and postsynaptic spikes. It has bee
Publikováno v:
BMC Neuroscience
Europe PubMed Central
BMC Neuroscience, Vol 8, Iss Suppl 2, p P85 (2007)
Europe PubMed Central
BMC Neuroscience, Vol 8, Iss Suppl 2, p P85 (2007)
Activity dependent synaptic plasticity is typically induced by delivering a large number (~1000) of highly regular electrical stimuli, designed to saturate the synaptic strengths. However, natural spike trains typically contain a small number of spik
Publikováno v:
Journal of neurophysiology. 97(1)
Various forms of synaptic plasticity, including spike timing-dependent plasticity, can be accounted for by calcium-dependent models of synaptic plasticity. However, recent results in which synaptic plasticity is induced by multi-spike protocols canno
Publikováno v:
Biological cybernetics. 95(2)
Although spike-timing-dependent plasticity (STDP) is well characterized when pre- and postsynaptic spikes are paired with a given time lag, how this generalizes for more complex spike-trains is unclear. Recent experiments demonstrate that contributio
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 101(41)
Modifications in the strengths of synapses are thought to underlie memory, learning, and development of cortical circuits. Many cellular mechanisms of synaptic plasticity have been investigated in which differential elevations of postsynaptic calcium
Publikováno v:
Physical Review E. 69
The influx of calcium ions into the dendritic spines through the N-metyl-D-aspartate (NMDA) channels is believed to be the primary trigger for various forms of synaptic plasticity. In this paper, the authors calculate analytically the mean values of
Publikováno v:
Biological cybernetics. 87(5-6)
Different mechanisms that could form the molecular basis for bi-directional synaptic plasticity have been identified experimentally and corresponding biophysical models can be constructed. However, such models are complex and therefore it is hard to