Unique, Specific CART Receptor-Independent Regulatory Mechanism of CART(55-102) Peptide in Spinal Nociceptive Transmission and Its Relation to Dipeptidyl-Peptidase 4 (DDP4).

Autor: Kozsurek M; Department of Anatomy, Histology and Embryology, Semmelweis University, H-1094 Budapest, Hungary., Király K; Department of Pharmacology and Pharmacotherapy, Semmelweis University, H-1089 Budapest, Hungary., Gyimesi K; Department of Anatomy, Histology and Embryology, Semmelweis University, H-1094 Budapest, Hungary.; Department of Anaesthesiology, Uzsoki Hospital, H-1145 Budapest, Hungary., Lukácsi E; Department of Anatomy, Histology and Embryology, Semmelweis University, H-1094 Budapest, Hungary., Fekete C; Laboratory of Integrative Neuroendocrinology, Institute of Experimental Medicine, Eötvös Loránd Research Network, H-1083 Budapest, Hungary.; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Tupper Research Institute, Tufts Medical Center, Boston, MA 02111, USA., Gereben B; Laboratory of Integrative Neuroendocrinology, Institute of Experimental Medicine, Eötvös Loránd Research Network, H-1083 Budapest, Hungary., Mohácsik P; Laboratory of Integrative Neuroendocrinology, Institute of Experimental Medicine, Eötvös Loránd Research Network, H-1083 Budapest, Hungary., Helyes Z; Department of Pharmacology and Pharmacotherapy, University of Pécs, H-7624 Pécs, Hungary.; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary.; Chronic Pain Research Group, Eötvös Loránd Research Network, H-7624 Pécs, Hungary., Bölcskei K; Department of Pharmacology and Pharmacotherapy, University of Pécs, H-7624 Pécs, Hungary., Tékus V; Department of Pharmacology and Pharmacotherapy, University of Pécs, H-7624 Pécs, Hungary.; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary., Pap K; Department of Orthopaedics and Traumatology, Uzsoki Hospital, H-1145 Budapest, Hungary., Szűcs E; Institute of Biochemistry, Biological Research Centre, Eötvös Loránd Research Network, H-6726 Szeged, Hungary., Benyhe S; Institute of Biochemistry, Biological Research Centre, Eötvös Loránd Research Network, H-6726 Szeged, Hungary., Imre T; MS Metabolomics Laboratory, Instrumentation Centre, Research Centre for Natural Sciences, Eötvös Loránd Research Network, H-1117 Budapest, Hungary., Szabó P; MS Metabolomics Laboratory, Instrumentation Centre, Research Centre for Natural Sciences, Eötvös Loránd Research Network, H-1117 Budapest, Hungary., Gajtkó A; Department of Anatomy, Histology and Embryology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary., Holló K; Department of Anatomy, Histology and Embryology, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary., Puskár Z; Department of Anatomy, Histology and Embryology, Semmelweis University, H-1094 Budapest, Hungary.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 04; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 04.

Glial cell type-specific changes in spinal dipeptidyl peptidase 4 expression and effects of its inhibitors in inflammatory and neuropatic pain.

Autor: Király K; Department of Pharmacology and Pharmacotherapy, Semmelweis University, H-1089, Budapest, Hungary., Kozsurek M; Department of Anatomy, Histology and Embryology, Semmelweis University, H-1094, Budapest, Hungary., Lukácsi E; Department of Anatomy, Histology and Embryology, Semmelweis University, H-1094, Budapest, Hungary., Barta B; Department of Anatomy, Histology and Embryology, Semmelweis University, H-1094, Budapest, Hungary., Alpár A; Department of Anatomy, Histology and Embryology, Semmelweis University, H-1094, Budapest, Hungary., Balázsa T; Department of Anatomy, Histology and Embryology, Semmelweis University, H-1094, Budapest, Hungary., Fekete C; 'Lendület' Laboratory of Integrative Neurobiology, Institute of Experimental Medicine of the Hungarian Academy of Sciences, H-1083, Budapest, Hungary., Szabon J; 'Lendület' Laboratory of Integrative Neurobiology, Institute of Experimental Medicine of the Hungarian Academy of Sciences, H-1083, Budapest, Hungary., Helyes Z; Department of Pharmacology and Pharmacotherapy, Medical School & Szentágothai Research Centre, University of Pécs, H-7624, Pécs, Hungary.; MTA-PTE NAP B Chronic Pain Research Group, University of Pécs, H-7624, Pécs, Hungary., Bölcskei K; Department of Pharmacology and Pharmacotherapy, Medical School & Szentágothai Research Centre, University of Pécs, H-7624, Pécs, Hungary., Tékus V; Department of Pharmacology and Pharmacotherapy, Medical School & Szentágothai Research Centre, University of Pécs, H-7624, Pécs, Hungary., Tóth ZE; Department of Anatomy, Histology and Embryology, Semmelweis University, H-1094, Budapest, Hungary., Pap K; Department of Traumatology, Semmelweis University, H-1113 Budapest, Hungary & Department of Orthopaedics and Traumatology, Uzsoki Hospital, H-1145, Budapest, Hungary., Gerber G; Department of Anatomy, Histology and Embryology, Semmelweis University, H-1094, Budapest, Hungary., Puskár Z; Department of Anatomy, Histology and Embryology, Semmelweis University, H-1094, Budapest, Hungary. puskar.zita@med.semmelweis-univ.hu.

Publikováno v: Scientific reports [Sci Rep] 2018 Feb 22; Vol. 8 (1), pp. 3490. Date of Electronic Publication: 2018 Feb 22.

Distribution and Chemistry of Phoenixin-14, a Newly Discovered Sensory Transmission Molecule in Porcine Afferent Neurons.

Autor: Mazur, Urszula¹ (AUTHOR) urszula.mazur@uwm.edu.pl, Lepiarczyk, Ewa¹ (AUTHOR) pawel.janikiewicz@uwm.edu.pl, Janikiewicz, Paweł¹ (AUTHOR) mariusz.majewski@uwm.edu.pl, Łopieńska-Biernat, Elżbieta² (AUTHOR) ela.lopienska@uwm.edu.pl, Majewski, Mariusz Krzysztof¹ (AUTHOR) agnieszka.bossowska@uwm.edu.pl, Bossowska, Agnieszka¹ (AUTHOR)

Publikováno v: International Journal of Molecular Sciences. Dec2023, Vol. 24 Issue 23, p16647. 25p.

Nonselective innervation of lamina I projection neurons by cocaine- and amphetamine-regulated transcript peptide (CART)-immunoreactive fibres in the rat spinal dorsal horn.

Autor: Kozsurek M; Department of Anatomy, Histology and Embryology, János Szentágothai Laboratory, Semmelweis University, Tuzoltó u. 58, 1094-Budapest, Hungary., Lukácsi E, Fekete C, Puskár Z

Publikováno v: The European journal of neuroscience [Eur J Neurosci] 2009 Jun; Vol. 29 (12), pp. 2375-87. Date of Electronic Publication: 2009 May 22.

Cocaine- and amphetamine-regulated transcript peptide (CART) is present in peptidergic C primary afferents and axons of excitatory interneurons with a possible role in nociception in the superficial laminae of the rat spinal cord.

Autor: Kozsurek M; Szentágothai Laboratory, Department of Anatomy, Histology and Embryology, Semmelweis University, Budapest, Hungary., Lukácsi E, Fekete C, Wittmann G, Réthelyi M, Puskár Z

Publikováno v: The European journal of neuroscience [Eur J Neurosci] 2007 Sep; Vol. 26 (6), pp. 1624-31.