Zobrazeno 1 - 10
of 357
pro vyhledávání: '"Lujun, Chen"'
Autor:
Yongqiang Lv, Chaolian Wang, Ruoyu Liu, Shaoxian Wu, Junjun Chen, Xiao Zheng, Tianwei Jiang, Lujun Chen
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Nuclear regulation has potential in cancer therapy, with the nuclear pore complex (NPC) serving as a critical channel between the nucleus and cytoplasm, playing a role in regulating various biological processes and cancer. DNA methylation, a
Externí odkaz:
https://doaj.org/article/77365348a24d4da7a6a9ced379390d6f
Autor:
Jiayi Yang, Xinyi Ding, Zhang Fang, Shaoxian Wu, Maoling Yuan, Rongzhang Chen, Qinlan Xu, Xinran Gao, Haoyu Wu, Lujun Chen, Xiao Zheng, Jingting Jiang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract CD8+T cells secreting granzyme A (GZMA) can induce pyroptosis in tumor cells by effectively cleaving gasdermin B (GSDMB), which is stimulated by interferon-γ (IFN-γ). However, the interaction between GZMA-expressing CD8+T cells and GSDMB-e
Externí odkaz:
https://doaj.org/article/2a6a89298a6f4656ac5255126ad989d9
Autor:
Lujun Chen, Qiulu Liang, Zhuoxin Lai, Haitao Cui, Zhenmin Xu, Zizhao Chen, Zhongdian Dong, Zhongduo Wang, Yusong Guo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Quantitative real-time PCR (qRT-PCR) has been widely employed for the study of gene expression in fish, and accurate normalization is crucial. In this study, we aimed to identify the most stably expressed genes in various tissues, different
Externí odkaz:
https://doaj.org/article/449c096cff3f42de8ea237486bfd0a01
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Regulatory T cells (Tregs), a subset of CD4+T cells marked by the expression of the transcription factor forkhead box protein 3 (Foxp3), are pivotal in maintaining immune equilibrium and preventing autoimmunity. In our review, we addressed the functi
Externí odkaz:
https://doaj.org/article/137eecfc94d1469b890cc7862bc30f2d
Autor:
Heming Li, Yang-Zhuangzhuang Zhu, Lu Xu, Tao Han, Jiasi Luan, Xin Li, Yuting Liu, Zhi Wang, Qiuge Liu, Xiangyu Kong, Chunpu Zou, Lin Su, Yifei Hou, Xiao Chen, Lujun Chen, Ruoyu Wang, Zihang Xu, Mingfang Zhao
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-22 (2024)
Abstract Background Circulating tumor cells (CTCs) hold immense promise in guiding treatment strategies for advanced gastric cancer (GC). However, their clinical impact has been limited due to challenges in identifying epithelial-mesenchymal transiti
Externí odkaz:
https://doaj.org/article/ab7045f91ec347d7b2182e7761958d1a
Autor:
Linyan Cheng, Lujun Chen, Yuan Shi, Weiying Gu, Weidong Ding, Xiao Zheng, Yan Liu, Jingting Jiang, Zhuojun Zheng
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-39 (2024)
Abstract Emerging tumor immunotherapy methods encompass bispecific antibodies (BSABs), immune checkpoint inhibitors (ICIs), and adoptive cell immunotherapy. BSABs belong to the antibody family that can specifically recognize two different antigens or
Externí odkaz:
https://doaj.org/article/2b194a1102bd4e979e67d005809eaf8b
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-9 (2023)
Abstract Hepatocellular carcinoma (HCC), one of the most prevalent forms of cancer worldwide, presents a significant global healthcare challenge. Cancer stem cells (CSCs), which can influence neighboring non-CSCs, are believed to play a crucial role
Externí odkaz:
https://doaj.org/article/2fe81ba662b84e999efc8362e100bcd6
Autor:
Lujun Chen, Karl-Heinz Pohl
This Open access book is a collection of interviews published by China News Service, a Beijing-based news agency, in its “West-East Talk” column. It has been divided into five sections: “Mutual Learning Among Civilizations,” “Hot Issues,”
Autor:
Junwei Ge, Junjun Chen, Qiong Shen, Xiao Zheng, Xuemin Chen, Liangrong Shi, Lujun Chen, Bin Xu
Publikováno v:
Cancer Control, Vol 31 (2024)
Background Immune-based therapies are commonly employed to combat hepatocellular carcinoma (HCC). However, the presence of immune-regulating elements, especially regulatory T cells (Tregs), can dramatically impact the treatment efficacy. A deeper exa
Externí odkaz:
https://doaj.org/article/0dfff4905b2842ea9bca68e97e6a5861
Autor:
Hao Huang, Junwei Ge, Zhang Fang, Shaoxian Wu, Hongwei Jiang, Yanyan Lang, Junjun Chen, Wenlu Xiao, Bin Xu, Yingting Liu, Lujun Chen, Xiao Zheng, Jingting Jiang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Exhausted CD8+T cells represent a distinct cellular lineage that emerges during both chronic infections and cancers. Recent studies have shown that persistent antigen exposure can drive the differentiation of precursor exhausted CD8+T cells, termed T
Externí odkaz:
https://doaj.org/article/7614ba27941e454292ab66f38bb2f6e8