Exploring the frequency of a TP53 polyadenylation signal variant in tumor DNA from patients diagnosed with lung adenocarcinomas, sarcomas and uterine leiomyomas

Autor: Igor Araujo Vieira, Guilherme Danielski Viola, Eduarda Heidrich Pezzi, Thayne Woycinck Kowalski, Bruna Vieira Fernandes, Tiago Finger Andreis, Natascha Bom, Giulianna Sonnenstrahl, Yasminne Marinho de Araújo Rocha, Bruno da Silveira Corrêa, Luiza Mezzomo Donatti, Gabriela dos Santos Sant’Anna, Helena von Eye Corleta, Ilma Simoni Brum, Clévia Rosset, Fernanda Sales Luiz Vianna, Gabriel S. Macedo, Edenir Inez Palmero, Patricia Ashton-Prolla

Publikováno v: Genetics and Molecular Biology, Vol 46, Iss 3 suppl 1 (2024)

Abstract The TP53 3’UTR variant rs78378222 A>C has been detected in different tumor types as a somatic alteration that reduces p53 expression through modification of polyadenylation and miRNA regulation. Its prevalence is not yet known in all tumor

Externí odkaz: https://doaj.org/article/1842083036564d94b5d4456d0ea54ce3

Primeiro bebê nascido no Brasil após diagnóstico simultâneo por PGT-A não-invasivo e convencional

Autor: Marcos Iuri Roos Kulmann, Márcia Riboldi, Carolina Martello, Adriana Bos-Mikich, Gerta Frantz, Caroline Dutra, Luiza Mezzomo Donatti, Norma Oliveira, Nilo Frantz

Publikováno v: Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
Revista Brasileira de Ginecologia e Obstetrícia, Vol 43, Iss 11, Pp 878-882 (2022)

Abordagens para o teste genético pré-implantacional não-invasivo para aneuploidias (non-invasive preimplantation genetic testing for aneuploidies, niPGT-A, em inglês) com o objetivo de avaliar o DNA embrionário livre são promissoras, especialme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e1d007ee2aebd989680a782b6ba203
https://doi.org/10.1055/s-0041-1736302

Preimplantation genetic testing for aneuploidies does not increase success rates in fresh oocyte donation cycles: a paired cohort study

Autor: Luiza Mezzomo Donatti, Marcos Iuri Roos Kulmann, Carolina Lumertz Martello, Adriana Bos-Mikich, Nilo Frantz

Publikováno v: J Assist Reprod Genet

PURPOSE: To determine whether in vitro fertilization cycles using fresh oocyte donations benefit from preimplantation genetic testing for aneuploidies. METHODS: A paired cohort study compared 44 fresh oocyte donation cycles with or without preimplant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83e9fd1463b3c05468a6ec430032122
https://pubmed.ncbi.nlm.nih.gov/34611788

Effects of aerobic exercise training on metabolism of nitric oxide and endothelin-1 in lung parenchyma of rats with pulmonary arterial hypertension

Autor: Luiza Mezzomo Donatti, Adriane Belló-Klein, Rafael Colombo, Jéssica Hellen Poletto Bonetto, Rayane Brinck Teixeira, Rafaela Siqueira, Isnard Elman Litvin, Alexsandra Zimmer, Alex Sander da Rosa Araujo, Alessandra Eifler Guerra Godoy, Alexandre Roberto Hickmann, Cristina Campos Carraro

Publikováno v: Molecular and cellular biochemistry. 429(1-2)

Pulmonary arterial hypertension (PAH) is characterized by vasoconstriction and proliferative obstruction of pulmonary vessels, which promotes a progressive increase in pulmonary vascular resistance (PVR). The effect of exercise training on oxidative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3285773c7e5dd38edb3d1ba7cf7ff95b
https://pubmed.ncbi.nlm.nih.gov/28181133