Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Luiza M.F. Gomes"'
Autor:
Jason R. Smith, Sherri A. McFarland, Camille Maunoir, Janaina C. Bataglioli, Houston D. Cole, Tariq Sainuddin, Tim Storr, Luiza M.F. Gomes, Julia McCain, Colin G. Cameron
Publikováno v:
Chemical Science. 12:7510-7520
Alzheimer's disease (AD) is a chronic neurodegenerative disorder characterized by progressive and irreversible damage to the brain. One of the hallmarks of the disease is the presence of both soluble and insoluble aggregates of the amyloid beta (Aβ)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b929fe13a6f469bde2821a273a975fff
https://doi.org/10.1039/d1sc00004g
https://doi.org/10.1039/d1sc00004g
Autor:
Zeev Gross, Tim Storr, Kathleen E. Prosser, Atif Mahammed, Luiza M.F. Gomes, Jason R. Smith, Michael A. Silverman, Charles J. Walsby
Publikováno v:
Chemical Science. 10:1634-1643
Alzheimer's disease (AD) is a multifaceted disease that is characterized by increased oxidative stress, metal-ion dysregulation, and the formation of intracellular neurofibrillary tangles and extracellular amyloid-β (Aβ) aggregates. In this work we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e03d8f1830f55bc5d3b1eb7d76c6a73a
https://doi.org/10.1039/c8sc04660c
https://doi.org/10.1039/c8sc04660c
Publikováno v:
Canadian Journal of Chemistry. 96:78-82
Multifunctional compounds that can modulate amyloid-β (Aβ) aggregation and interact with metal ions hold considerable promise as therapeutic agents for Alzheimer’s disease (AD). Using the copper-catalyzed azide-alkyne cycloaddition reaction, a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63156b1dd071c70078b70ff3c171eedd
https://doi.org/10.1139/cjc-2017-0623
https://doi.org/10.1139/cjc-2017-0623
Autor:
Jason R. Smith, Charles J. Walsby, Tim Storr, Allison J. Jussila, Janaina C. Bataglioli, Luiza M.F. Gomes
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, Vol 7 (2019)
Frontiers in Chemistry, Vol 7 (2019)
Alzheimer's disease (AD) is the most common form of dementia, leading to loss of cognition, and eventually death. The disease is characterized by the formation of extracellular aggregates of the amyloid-beta (Aβ) peptide and neurofibrillary tangles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395a2b725ebc4d952052545ff057edfa
https://pubmed.ncbi.nlm.nih.gov/31921764
https://pubmed.ncbi.nlm.nih.gov/31921764
Publikováno v:
Coordination Chemistry Reviews. 412:213255
Alzheimer’s disease (AD) is the most common form of dementia, and is a multi-faceted disease that is characterized by oxidative stress, metal-ion dysregulation, and the formation of intracellular neurofibrillary tangles of tau protein and extracell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bee250d640c6256b8764aff440ca8f74
https://doi.org/10.1016/j.ccr.2020.213255
https://doi.org/10.1016/j.ccr.2020.213255
Autor:
Rafael P. Vieira, Tim Storr, Heloisa Beraldo, Luiza M.F. Gomes, Michael R. Jones, Elaine M. Souza-Fagundes, Christine Dyrager, Michael C. P. Wang, Jeferson G. Da Silva
Publikováno v:
Journal of Inorganic Biochemistry. 139:106-116
One of the hallmarks of Alzheimer's disease (AD) in the brain are amyloid-β (Aβ) plaques, and metal ions such as copper(II) and zinc(II) have been shown to play a role in the aggregation and toxicity of the Aβ peptide, the major constituent of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8584278b1394345a172be38d3e6ddb
https://doi.org/10.1016/j.jinorgbio.2014.04.011
https://doi.org/10.1016/j.jinorgbio.2014.04.011