Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Luiza Filipis"'
Autor:
Laila Ananda Blömer, Elisabetta Giacalone, Fatima Abbas, Luiza Filipis, Domenico Tegolo, Michele Migliore, Marco Canepari
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The back-propagation of an action potential (AP) from the axon/soma to the dendrites plays a central role in dendritic integration. This process involves an intricate orchestration of various ion channels, but a comprehensive understanding of the con
Externí odkaz:
https://doaj.org/article/a672d584ea0f4396920981f2b531acdf
Autor:
Luiza Filipis, Marco Canepari
Publikováno v:
Frontiers in Computational Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/081a5c11f383489e8e4629ea224604c3
Autor:
Jérôme Montnach, Laila Ananda Blömer, Ludivine Lopez, Luiza Filipis, Hervé Meudal, Aude Lafoux, Sébastien Nicolas, Duong Chu, Cécile Caumes, Rémy Béroud, Chris Jopling, Frank Bosmans, Corinne Huchet, Céline Landon, Marco Canepari, Michel De Waard
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Photoactivable toxins targeting ion channels have great potential to control cell activity. Here the authors report HwTxIV-Nvoc, a UV light-cleavable and photoactivatable peptide that targets voltage-gated sodium channels; they validate this in cells
Externí odkaz:
https://doaj.org/article/423c1529d3814c50834a3cc0ac0261d0
Autor:
Luiza Filipis, Laila Ananda Blömer, Jérôme Montnach, Gildas Loussouarn, Michel De Waard, Marco Canepari
Publikováno v:
The Journal of Physiology. 601:1957-1979
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5235fa3f9feaeed13ac21acecbce2ed1
https://doi.org/10.1113/jp283801
https://doi.org/10.1113/jp283801
Publikováno v:
Journal of Fluorescence. 31:619-623
Ultrafast Ca2+ imaging using low-affinity fluorescent indicators allows the precise measurement of the kinetics of fast Ca2+ currents mediated by voltage-gated Ca2+ channels. Thus far, only a few indicators provided fluorescence transients with suffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23c19d5ee3f6b8a882e7872101619768
https://doi.org/10.1007/s10895-021-02701-8
https://doi.org/10.1007/s10895-021-02701-8
In neocortical layer-5 pyramidal neurons, the action potential (AP) is generated in the axon initial segment (AIS) when the membrane potential (Vm) reaches the threshold for activation of two diverse voltage-gated Na+ channels, that differ in spatial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0392b6d9426b73ebc6762c09d273c5a
https://doi.org/10.1101/2022.04.12.488116
https://doi.org/10.1101/2022.04.12.488116
Publikováno v:
Current Protocols in Bioinformatics
Current Protocols in Bioinformatics, Wiley, 2021, 1 (3), ⟨10.1002/cpz1.64⟩
Current Protocols in Bioinformatics, Wiley, 2021, 1 (3), ⟨10.1002/cpz1.64⟩
Monitoring Na+ influx in the axon initial segment (AIS) at high spatial and temporal resolution is fundamental to understanding the generation of an action potential (AP). Here, we present protocols to obtain this measurement, focusing on the AIS of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccf30983c0e5e867683879a4e4b351e6
https://hal.archives-ouvertes.fr/hal-03179745/document
https://hal.archives-ouvertes.fr/hal-03179745/document
Autor:
Luiza Filipis, Marco Canepari
Publikováno v:
The Journal of Physiology
The Journal of Physiology, Wiley, 2021, 599 (1), pp.49-66. ⟨10.1113/JP280554⟩
The Journal of Physiology, Wiley, 2021, 599 (1), pp.49-66. ⟨10.1113/JP280554⟩
Key points Τhe axonal Na+ fluorescence underlying an action potential in the axon initial segment was optically measured at unprecedented temporal resolution. The measurement allowed resolution of the kinetics of the Na+ current at different axonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6dcadd563c4f90e2ed115850f1344a8
https://hal.archives-ouvertes.fr/hal-03109314/file/Filipis_Canepari_Article.pdf
https://hal.archives-ouvertes.fr/hal-03109314/file/Filipis_Canepari_Article.pdf
Publikováno v:
Journal of fluorescence. 31(3)
Ultrafast Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ee402b36e28b4c66226be2b11ed6493
https://pubmed.ncbi.nlm.nih.gov/33606130
https://pubmed.ncbi.nlm.nih.gov/33606130