Výsledky vyhledávání - "Luiza A. Nogaj"

Akademický článek

Inhibition of toxic IAPP amyloid by extracts of common fruits

Autor: Pei-Yu Kao, Evangeline Green, Catalina Pereira, Shauna Ekimura, Dennis Juarez, Travis Whyte, Taylor Arhar, Bianca Malaspina, Luiza A. Nogaj, David A. Moffet

Publikováno v: Journal of Functional Foods, Vol 12, Iss , Pp 450-457 (2015)

The aggregation of the 37-amino acid polypeptide islet amyloid polypeptide (IAPP, amylin), as either insoluble amyloid or as small oligomers, appears to play a direct role in the death of pancreatic β-islet cells in type 2 diabetes. It is believed t

Externí odkaz: https://doaj.org/article/909d2d234be742d693d807ee54140a27

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Nonhuman IAPP Variants Inhibit Human IAPP Aggregation

Autor: Betssy Jauregui, Kate Menefee, David A. Moffet, Angela Tun, Luiza A. Nogaj, Alissa K. Oakes, Arleen Lamba, Larry M. Palato, Kevin Chang, Dillon J. Rinauro

Publikováno v: Protein and peptide letters. 28(9)

Aim: To identify naturally occurring variants of IAPP capable of inhibiting the aggregation of human IAPP and protecting living cells from the toxic effects of human IAPP. Background: The loss of insulin-producing β-cells and the overall progression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e40f8d7b2e695736772f51c9627341
https://pubmed.ncbi.nlm.nih.gov/34365921

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Amyloidogenicity of naturally occurring full-length animal IAPP variants

Autor: Betssy Jauregui, Kate Menefee, Alissa K. Oakes, Viviane Nguyen, David A. Moffet, Litza Itzel Ledesma Monjaraz, Shannon Pilcher, Crystabel Munoz, Luiza A. Nogaj, Kevin Chang, Dillon J. Rinauro, Jaris Torres, Edward Njoo, Angela Tun, Arleen Lamba, Olivia H. Nossiff, Eileen Olivares, Larry M. Palato, Sarah Shapiro

Publikováno v: J Pept Sci

The aggregation of the 37-amino acid polypeptide human islet amyloid polypeptide (hIAPP), as either insoluble amyloid or as small oligomers, appears to play a direct role in the death of human pancreatic β-islet cells in type 2 diabetes. hIAPP is co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a004e4900afc9cc7d71c9e20b81c8265
https://pubmed.ncbi.nlm.nih.gov/31231935

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Identification of plant extracts that inhibit the formation of diabetes-linked IAPP amyloid

Autor: In Wang, Cynthia Chaggan, Jacob Pascual, David A. Moffet, Kathleen Hennessy, Ana Lucia Fuentes, Alexander Santiago, Luiza A. Nogaj, Christina Cunha, Jessica Martinez, Evelyn Rivera, Nicole T.M. Pepe, Paola Cota

Publikováno v: Journal of Herbal Medicine. 6:37-41

The extracts of 27 vegetables, spices and herbs were screened for their functional ability to inhibit the aggregation of islet amyloid polypeptide (IAPP, amylin) into toxic amyloid aggregates. The aggregation of IAPP has been directly linked to the d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40878878c658c814a2b89e451e183ad4
https://doi.org/10.1016/j.hermed.2015.11.001

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