Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Luiz S. Capella"'
Autor:
Luiz S. Capella, Raphael C. Valente, Márcia M. M. Oliveira, Marcia A. M. Capella, Luciana T. Nunes-Lima, Fernanda C. M. Cruz, Roberta R. Palmieri, Anibal Gil Lopes
Publikováno v:
Cell Biology and Toxicology. 26:201-213
The cellular actions of ouabain are complex and involve different pathways, depending on the cell type and experimental conditions. Several studies have reported that Madin-Darby canine kidney (MDCK) cellular sensitivity to ouabain is not related to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f52de36d20c529d62c66fa1cc375ff
https://doi.org/10.1007/s10565-009-9136-8
https://doi.org/10.1007/s10565-009-9136-8
Publikováno v:
Cell Biology and Toxicology. 23:413-420
Vanadium is an environmentally toxic metal with peculiar and sometimes contradictory cellular effects. It is insulin-mimetic, it can either stimulate cell growth or induce cell death, and it has both mutagenic and antineoplastic properties. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe78849ebb05644495fccb5ac05f577c
https://doi.org/10.1007/s10565-007-9003-4
https://doi.org/10.1007/s10565-007-9003-4
Autor:
Marcia A. M. Capella, Clarissa Rodrigues Nascimento, Anibal Gil Lopes, Luiz S. Capella, Raphael C. Valente
Publikováno v:
Cell Biology and Toxicology. 23:421-427
Besides being a (Na(+),K(+))-ATPase inhibitor, high doses of the hormone ouabain have also been reported to modulate both the expression and activity of proteins belonging to the ATP binding cassette family of transporters, such as ABCC7 (CFTR), ABCB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b870542b496a500b6914ee9e7183e5
https://doi.org/10.1007/s10565-007-9004-3
https://doi.org/10.1007/s10565-007-9004-3
Autor:
Omar R. Santos, Luiz S. Capella, Clarissa Rodrigues Nascimento, Marcia A. M. Capella, Anibal Gil Lopes, Filipe Braga
Publikováno v:
Nephron Experimental Nephrology. 99:e77-e86
Background: Although cyclosporin A (CSA) inhibits P-glycoprotein (ABCB1), the relationship between this inhibition and CSA-induced nephrotoxicity is not established. Methods: Three renal cell lines were used to investigate the effects of CSA in cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b4444bf129da2ed0e2407b809dcff8
https://doi.org/10.1159/000083415
https://doi.org/10.1159/000083415
Autor:
Anibal Gil Lopes, Maria R Gefé, Marcia A. M. Capella, Luiz S. Capella, Edson Ferreira da Silva, Vivian M. Rumjanek, Ottilia R. Affonso-Mitidieri
Publikováno v:
Archives of Biochemistry and Biophysics. 406:65-72
Besides its insulin-mimetic effects, vanadate is also known to have a variety of physiological and pharmacological properties, varying from induction of cell growth to cell death and is also a modulator of the multidrug resistance phenotype. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d061c02f3769c7c2094ccb94512dd9a3
https://doi.org/10.1016/s0003-9861(02)00408-3
https://doi.org/10.1016/s0003-9861(02)00408-3
Autor:
Anibal Gil Lopes, Marcia A. M. Capella, Luiz S. Capella, Vivaldo Moura-Neto, Janaina S.M. Alcantara
Publikováno v:
Tumor Biology. 21:54-62
The development of multidrug resistance (MDR) is the primary cause of failure of cancer chemotherapy and circumventing this problem is a major challenge in oncology. Vanadate is known to inhibit the ATPase activity of the P-glycoprotein and multidrug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8923ffcf4d8c487804be87bee18c8fe4
https://doi.org/10.1159/000030111
https://doi.org/10.1159/000030111
Autor:
Fernanda Kyle-Cezar, Juliana Echevarria-Lima, Luiz S. Capella, Daniela F. P. Leite, Vivian M. Rumjanek, Marcia A. M. Capella
Publikováno v:
Immunology. 114(4)
Multidrug resistance proteins [MRPs and P-glycoprotein (Pgp)] are members of the family of ATP-binding cassette (ABC) transport proteins, originally described as being involved in the resistance against anti-cancer agents in tumour cells. These prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff8d2b962814ad443cdf3887e3ae2cf
https://pubmed.ncbi.nlm.nih.gov/15804283
https://pubmed.ncbi.nlm.nih.gov/15804283
Autor:
Luiz S. Capella, Marcia A. M. Capella
Publikováno v:
Journal of biomedical science. 10(4)
The major drawback of cancer chemotherapy is the development of multidrug-resistant (MDR) tumor cells, which are cross-resistant to a broad range of structurally and functionally unrelated agents, making it difficult to treat these tumors. In the las
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59169641278a49db61655f9007fa03de
https://pubmed.ncbi.nlm.nih.gov/12824695
https://pubmed.ncbi.nlm.nih.gov/12824695