Výsledky vyhledávání - "Luiz S Aroeira"

Akademický článek

Paricalcitol reduces peritoneal fibrosis in mice through the activation of regulatory T cells and reduction in IL-17 production.

Autor: Guadalupe T González-Mateo, Vanessa Fernández-Míllara, Teresa Bellón, Georgios Liappas, Marta Ruiz-Ortega, Manuel López-Cabrera, Rafael Selgas, Luiz S Aroeira

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e108477 (2014)

Fibrosis is a significant health problem associated with a chronic inflammatory reaction. The precise mechanisms involved in the fibrotic process are still poorly understood. However, given that inflammation is a major causative factor, immunomodulat

Externí odkaz: https://doaj.org/article/1f524c6931bd446686c7476c35d3c49b

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Sensitive and non-invasive method for the in vivo analysis of membrane permeability in small animals

Autor: Carla Regueiro-Rodríguez, Luiz S. Aroeira, David N. Olivieri, África González-Fernández, Andrea Fernandez-Carrera, Eva Vigo

Publikováno v: Laboratory Investigation. 97:1114-1120

Tissue membranes are boundaries that isolate organs or cavities in the body. These semi-permeable membranes are responsible for passive protection that acts through the regulation of nutrient absorption, secretion and filtration of small molecules. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1e5de16f678f2327f5d66938c90085
https://doi.org/10.1038/labinvest.2017.66

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IL-17A is a novel player in dialysis-induced peritoneal damage

Autor: Manuel López-Cabrera, Luiz S. Aroeira, Alberto Ortiz, Guadalupe González-Mateo, Raúl R. Rodrigues-Diez, Bajo Ma, Raquel Rodrigues-Díez, Marta Ruiz-Ortega, Rafael Selgas, José Jiménez Heffernan, Macarena Orejudo, Jesús Egido, Sandra Rayego-Mateos

Publikováno v: Kidney International. 86:303-315

The classical view of the immune system has changed by the discovery of novel T-helper (Th) subsets, including Th17 (IL-17A-producing cells). IL-17A participates in immune-mediated glomerulonephritis and more recently in inflammatory pathologies, inc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5973d419fb86b34b312df7b865182e
https://doi.org/10.1038/ki.2014.33

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The C-terminal module IV of connective tissue growth factor is a novel immune modulator of the Th17 response

Autor: Sandra Rayego-Mateos, Elsa Sanchez-Lopez, Beatriz Suarez-Alvarez, Luiz S. Aroeira, Carolina Lavoz, Matilde Alique, Macarena Orejudo, Marta Ruiz-Ortega, Raquel Rodrigues-Díez, Carlos López-Larrea, Raúl R. Rodrigues-Diez, Jesús Egido, Alberto Ortiz

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Connective tissue growth factor (CTGF/CCN2) is a matricellular protein susceptible to proteolytic degradation. CCN2 levels have been suggested as a potential risk biomarker in several chronic diseases. In body fluids, CCN2 full-length and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af74ee7af66e1ddb442e5ee33481487
https://doi.org/10.1038/labinvest.2013.67

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BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure

Autor: M. Luisa Pérez-Lozano, Abelardo Aguilera, Lorea Mendoza, Jacob van den Born, Patricia Albar-Vizcaíno, Guadalupe González-Mateo, Marta Ruiz-Ortega, Marta Ramírez-Huesca, Jesús Loureiro, Robert H. J. Beelen, Manuel López-Cabrera, Alberto Ortiz, Rafael Selgas, Margot N. Schilte, Luiz S. Aroeira

Publikováno v: Nephrology, Dialysis, Transplantation, 25(4), 1098-1108. Oxford University Press
Loureiro, J, Schilte, M N, Aguilera, A, Albar-Vizcaino, P, Ramirez-Huesca, M, Perez-Lozano, M L, Gonzalez-Mateo, G, Aroeira, L S, Selgas, R, Mendoza, L, Ortiz, A, Ruiz-Ortega, M, van den Born, J, Beelen, R H J & Lopez-Cabrera, M 2010, ' BMP-7 blocks mesenchymal conversion of mesothelial cells and prevents peritoneal damage induced by dialysis fluid exposure ', Nephrology, Dialysis, Transplantation, vol. 25, no. 4, pp. 1098-1108 . https://doi.org/10.1093/ndt/gfp618

BACKGROUND: During peritoneal dialysis (PD), mesothelial cells (MC) undergo an epithelial-to-mesenchymal transition (EMT), and this process is associated with peritoneal membrane (PM) damage. Bone morphogenic protein-7 (BMP-7) antagonizes transformin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86da525c51d65cb7cc762c73bfa60b5a
https://doi.org/10.1093/ndt/gfp618

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CTGF Promotes Inflammatory Cell Infiltration of the Renal Interstitium by Activating NF-κB

Autor: Sergio Mezzano, Raquel Rodrigues-Díez, Gisselle Carvajal, Elsa Sanchez-Lopez, Marta Ruiz-Ortega, Rafael Selgas, Alberto Ortiz, Raúl R. Rodrigues-Diez, Luiz S. Aroeira, Javier Sánchez Rodriguez, Sandra Rayego, Juan Rodriguez-Vita, Jesús Egido

Publikováno v: JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
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Connective tissue growth factor (CTGF) is an important profibrotic factor in kidney diseases. Blockade of endogenous CTGF ameliorates experimental renal damage and inhibits synthesis of extracellular matrix in cultured renal cells. CTGF regulates sev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d27e7b2471c31b4187d4654bee65c23
https://doi.org/10.1681/asn.2008090999

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Cyclooxygenase-2 Mediates Dialysate-Induced Alterations of the Peritoneal Membrane

Autor: Manuel López-Cabrera, Marta Ramírez-Huesca, José A. Jiménez-Heffernan, José Antonio Sánchez-Tomero, Luiz S. Aroeira, Bajo Ma, Gloria del Peso, Rafael Selgas, M. Luisa Pérez-Lozano, Abelardo Aguilera, Patricia Albar-Vizcaíno, Guadalupe González-Mateo, Jesús Loureiro, Enrique Lara-Pezzi

Publikováno v: Journal of the American Society of Nephrology. 20:582-592

During peritoneal dialysis (PD), exposure of the peritoneal membrane to nonphysiologic solutions causes inflammation, ultimately leading to altered structure and function. Myofibroblasts, one of the cell types that contribute to dysfunction of the pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ae06ed54c093ee6202a837fe2aa3a0
https://doi.org/10.1681/asn.2008020211

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Characterization of Epithelial-to-Mesenchymal Transition of Mesothelial Cells in a Mouse Model of Chronic Peritoneal Exposure to High Glucose Dialysate

Autor: José Antonio Sánchez-Tomero, Jesús Loureiro, Rafael Selgas, Marta Ruiz-Ortega, Gloria del Peso, M. Auxiliadora Bajo, Guadalupe González-Mateo, Manuel López-Cabrera, Luiz S. Aroeira, Vanessa Fernandez-Millara

Publikováno v: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis. 28:29-33

Animal models of peritoneal dialysis fluid (PDF) exposure are key tools in the study of mechanisms involved in alterations of the peritoneal membrane and in the design of therapies. We recently developed a mouse model of chronic peritoneal exposure t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a834c588fa4c6ee4217e577b751fb259
https://doi.org/10.1177/089686080802805s06

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Tissue distribution of hyalinazing vasculopathy lesions in peritoneal dialysis patients

Autor: M. Luz Picazo, Manuel López-Cabrera, Rafael Selgas, Eva Tejerina, Cristian Perna, M. Auxiliadora Bajo, Luiz S. Aroeira, Abelardo Aguilera, Gloria del Peso, José A. Jiménez-Heffernan

Publikováno v: Pathology - Research and Practice. 204:563-567

Uremia is considered capable of inducing structural anomalies of the peritoneum, including hyalinizing vasculopathy (HV). To further elucidate the contribution of uremia to the severity of HV, we performed an autopsy study of peritoneal dialysis (PD)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::885ec6ec25a5a62098aaaf963001ef9f
https://doi.org/10.1016/j.prp.2008.01.014

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