In vitro evaluation of the genotoxic activity and apoptosis induction of the extracts of roots and leaves from the medicinal plant Coccoloba mollis (Polygonaceae)

Autor: Tsuboy MS, Marcarini JC, Luiz RC, Barros IB, Ferreira DT, Ribeiro LR, Mantovani MS

Publikováno v: Journal of Medicinal Food; Jun2010, Vol. 13 Issue 3, p503-508, 6p

Metformin pretreatment reduces effect to dacarbazine and suppresses melanoma cell resistance.

Autor: Sanches LJ; Department of Pathological Sciences, Laboratory of Molecular Pathology, Londrina State University, UEL, Londrina, Parana, Brazil., Marinello PC; Department of Pathological Sciences, Laboratory of Molecular Pathology, Londrina State University, UEL, Londrina, Parana, Brazil., da Silva Brito WA; Department of Pathological Sciences, Laboratory of Molecular Pathology, Londrina State University, UEL, Londrina, Parana, Brazil.; Leibniz-Institute for Plasma Science and Technology (INP Greifswald), ZIK plasmatis 'Plasma Redox Effects', Greifswald, Germany., Lopes NMD; Department of Pathological Sciences, Laboratory of Molecular Pathology, Londrina State University, UEL, Londrina, Parana, Brazil., Luiz RC; Department of Pathological Sciences, Laboratory of Pathophysiology and Free radicals, Londrina State University, UEL, Londrina, Parana, Brazil., Cecchini R; Department of Pathological Sciences, Laboratory of Pathophysiology and Free radicals, Londrina State University, UEL, Londrina, Parana, Brazil., Cecchini AL; Department of Pathological Sciences, Laboratory of Molecular Pathology, Londrina State University, UEL, Londrina, Parana, Brazil.

Publikováno v: Cell biology international [Cell Biol Int] 2022 Jan; Vol. 46 (1), pp. 73-82. Date of Electronic Publication: 2021 Sep 21.

The progression of metastatic melanoma augments a pro-oxidative milieu locally but not systemically.

Autor: Pasqual-Melo G; Laboratory of Molecular Pathology, State University of Londrina, Brazil; Laboratory of Pathophysiology and Free Radicals, State University of Londrina, Brazil; ZIK Plasmatis, Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany., Bernardes SS; Laboratory of Molecular Pathology, State University of Londrina, Brazil; Laboratory of Tissue Microenvironment, Federal University of Minas Gerais, Brazil., Souza-Neto FP; Laboratory of Molecular Pathology, State University of Londrina, Brazil; Laboratory of Pathophysiology and Free Radicals, State University of Londrina, Brazil., Carrara IM; Laboratory of Molecular Pathology, State University of Londrina, Brazil; Laboratory of Pathophysiology and Free Radicals, State University of Londrina, Brazil., Ramalho LNZ; Department of Pathology and Legal Medicine, University of São Paulo, Brazil., Marinello PC; Laboratory of Molecular Pathology, State University of Londrina, Brazil., Luiz RC; Laboratory of Molecular Pathology, State University of Londrina, Brazil., Cecchini R; Laboratory of Pathophysiology and Free Radicals, State University of Londrina, Brazil., Bekeschus S; ZIK Plasmatis, Leibniz Institute for Plasma Science and Technology (INP), Greifswald, Germany., Cecchini AL; Laboratory of Molecular Pathology, State University of Londrina, Brazil; Laboratory of Pathophysiology and Free Radicals, State University of Londrina, Brazil. Electronic address: alcecchini@uel.br.

Publikováno v: Pathology, research and practice [Pathol Res Pract] 2020 Nov; Vol. 216 (11), pp. 153218. Date of Electronic Publication: 2020 Sep 23.

Oxidative stress and TGF-β1 induction by metformin in MCF-7 and MDA-MB-231 human breast cancer cells are accompanied with the downregulation of genes related to cell proliferation, invasion and metastasis.

Autor: Marinello PC; Laboratory of Molecular Pathology, Department of Pathological Sciences, State University of Londrina (UEL), Londrina, PR, Brazil., Panis C; Laboratory of Tumor Biology, State University of West Paraná (Unioeste), Francisco Beltrão, PR, Brazil., Silva TNX; Laboratory of Molecular Pathology, Department of Pathological Sciences, State University of Londrina (UEL), Londrina, PR, Brazil., Binato R; Stem Cell Laboratory, Bone Marrow Transplantation Unit, National Cancer Institute (INCA), Rio de Janeiro, RJ, Brazil., Abdelhay E; Stem Cell Laboratory, Bone Marrow Transplantation Unit, National Cancer Institute (INCA), Rio de Janeiro, RJ, Brazil., Rodrigues JA; Laboratory of Cancer Biology, Department of Biophysics and Biometrics, State University of Rio de Janeiro (UERJ), Rio de Janeiro, RJ, Brazil., L Mencalha A; Laboratory of Cancer Biology, Department of Biophysics and Biometrics, State University of Rio de Janeiro (UERJ), Rio de Janeiro, RJ, Brazil., Lopes NMD; Laboratory of Molecular Pathology, Department of Pathological Sciences, State University of Londrina (UEL), Londrina, PR, Brazil., Borges FH; Laboratory of Pathophysiology and Free Radicals, Department of Pathological Sciences, State University of Londrina (UEL), Londrina, PR, Brazil., Luiz RC; Laboratory of Molecular Pathology, Department of Pathological Sciences, State University of Londrina (UEL), Londrina, PR, Brazil., Cecchini R; Laboratory of Pathophysiology and Free Radicals, Department of Pathological Sciences, State University of Londrina (UEL), Londrina, PR, Brazil., Cecchini AL; Laboratory of Molecular Pathology, Department of Pathological Sciences, State University of Londrina (UEL), Londrina, PR, Brazil. Electronic address: alcecchini@uel.br.

Publikováno v: Pathology, research and practice [Pathol Res Pract] 2020 Oct; Vol. 216 (10), pp. 153135. Date of Electronic Publication: 2020 Jul 26.

Looking beyond the skin: Cutaneous and systemic oxidative stress in UVB-induced squamous cell carcinoma in hairless mice.

Autor: Carrara IM; Laboratory of Molecular Pathology, Londrina State University (UEL), Londrina, Paraná, Brazil, UEL, Rod. Celso Garcia Cid, PR-445, km 380, 86051-990 Londrina, Paraná, Brazil; Laboratory of Pathophysiology and Free Radicals, Londrina State University (UEL), Londrina, Paraná, Brazil, UEL, Rod. Celso Garcia Cid, PR-445, km 380, 86051-990 Londrina, Paraná, Brazil., Melo GP; Laboratory of Molecular Pathology, Londrina State University (UEL), Londrina, Paraná, Brazil, UEL, Rod. Celso Garcia Cid, PR-445, km 380, 86051-990 Londrina, Paraná, Brazil; Laboratory of Pathophysiology and Free Radicals, Londrina State University (UEL), Londrina, Paraná, Brazil, UEL, Rod. Celso Garcia Cid, PR-445, km 380, 86051-990 Londrina, Paraná, Brazil., Bernardes SS; Laboratory of Molecular Pathology, Londrina State University (UEL), Londrina, Paraná, Brazil, UEL, Rod. Celso Garcia Cid, PR-445, km 380, 86051-990 Londrina, Paraná, Brazil; Laboratory of Healthy Sciences Research, Federal University of Grande Dourados (UFGD), Dourados, Mato Grosso do Sul, Brazil, UFGD, R. João Rosa Góes, 1761 - Vila Progresso, Dourados, MS, 79825-070, Brazil. Electronic address: sarabernardes@ufgd.edu.br., Neto FS; Laboratory of Molecular Pathology, Londrina State University (UEL), Londrina, Paraná, Brazil, UEL, Rod. Celso Garcia Cid, PR-445, km 380, 86051-990 Londrina, Paraná, Brazil; Laboratory of Pathophysiology and Free Radicals, Londrina State University (UEL), Londrina, Paraná, Brazil, UEL, Rod. Celso Garcia Cid, PR-445, km 380, 86051-990 Londrina, Paraná, Brazil., Ramalho LNZ; Department of Pathology, Ribeirão Preto Medical School (FMRP), University of São Paulo (USP), FMRP, Av. Bandeirantes, 3900 - Monte Alegre, Ribeirão Preto, SP, 14049-900, Brazil. Electronic address: lramalho@fmrp.usp.br., Marinello PC; Laboratory of Molecular Pathology, Londrina State University (UEL), Londrina, Paraná, Brazil, UEL, Rod. Celso Garcia Cid, PR-445, km 380, 86051-990 Londrina, Paraná, Brazil., Luiz RC; Laboratory of Molecular Pathology, Londrina State University (UEL), Londrina, Paraná, Brazil, UEL, Rod. Celso Garcia Cid, PR-445, km 380, 86051-990 Londrina, Paraná, Brazil., Cecchini R; Laboratory of Pathophysiology and Free Radicals, Londrina State University (UEL), Londrina, Paraná, Brazil, UEL, Rod. Celso Garcia Cid, PR-445, km 380, 86051-990 Londrina, Paraná, Brazil., Cecchini AL; Laboratory of Molecular Pathology, Londrina State University (UEL), Londrina, Paraná, Brazil, UEL, Rod. Celso Garcia Cid, PR-445, km 380, 86051-990 Londrina, Paraná, Brazil. Electronic address: alcecchini@yahoo.com.

Publikováno v: Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2019 Jun; Vol. 195, pp. 17-26. Date of Electronic Publication: 2019 Apr 16.