Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Luiz O Leiria"'
Autor:
Mari Sato, Tadataka Tsuji, Kunyan Yang, Xiaozhi Ren, Jonathan M Dreyfuss, Tian Lian Huang, Chih-Hao Wang, Farnaz Shamsi, Luiz O Leiria, Matthew D Lynes, King-Wai Yau, Yu-Hua Tseng
Publikováno v:
PLoS Biology, Vol 18, Iss 2, p e3000630 (2020)
Opsin3 (Opn3) is a transmembrane heptahelical G protein-coupled receptor (GPCR) with the potential to produce a nonvisual photoreceptive effect. Interestingly, anatomical profiling of GPCRs reveals that Opn3 mRNA is highly expressed in adipose tissue
Externí odkaz:
https://doaj.org/article/796dbcea1d5e487694fa40a3e9fa5947
Autor:
Luiz O Leiria, Carolina Sollon, Marina C Calixto, Letícia Lintomen, Fabíola Z Mónica, Gabriel F Anhê, Gilberto De Nucci, Angelina Zanesco, Andrew D Grant, Edson Antunes
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48507 (2012)
Obesity/metabolic syndrome are common risk factors for overactive bladder. This study aimed to investigate the functional and molecular changes of detrusor smooth muscle (DSM) in high-fat insulin resistant obese mice, focusing on the role of protein
Externí odkaz:
https://doaj.org/article/3fd31b1e20ca40359c22230386b9b370
Autor:
Bruna M. Silva, Giovanni F. Gomes, Flavio P. Veras, Seppe Cambier, Gabriel V.L. Silva, Andreza U. Quadros, Diego B. Caetité, Daniele C. Nascimento, Camilla M. Silva, Juliana C. Silva, Samara Damasceno, Ayda H. Schneider, Fabio Beretta, Sabrina S. Batah, Icaro M.S. Castro, Isadora M. Paiva, Tamara Rodrigues, Ana Salina, Ronaldo Martins, Guilherme C.M. Cebinelli, Naira L. Bibo, Daniel M. Jorge, Helder I. Nakaya, Dario S. Zamboni, Luiz O. Leiria, Alexandre T. Fabro, José C. Alves-Filho, Eurico Arruda, Paulo Louzada-Junior, Renê D. Oliveira, Larissa D. Cunha, Pierre Van Mol, Lore Vanderbeke, Simon Feys, Els Wauters, Laura Brandolini, Andrea Aramini, Fernando Q. Cunha, Jörg Köhl, Marcello Allegretti, Diether Lambrechts, Joost Wauters, Paul Proost, Thiago M. Cunha
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that complement component 5a (C5a), through its cellular receptor C5aR1, has pote
Externí odkaz:
https://doaj.org/article/a119f5892a0d43a4859a59ccd6f0ea4d
Autor:
Matthew D. Lynes, Farnaz Shamsi, Elahu Gosney Sustarsic, Luiz O. Leiria, Chih-Hao Wang, Sheng-Chiang Su, Tian Lian Huang, Fei Gao, Niven R. Narain, Emily Y. Chen, Aaron M. Cypess, Tim J. Schulz, Zachary Gerhart-Hines, Michael A. Kiebish, Yu-Hua Tseng
Publikováno v:
Cell Reports, Vol 24, Iss 3, Pp 781-790 (2018)
Summary: Thermogenic fat expends energy during cold for temperature homeostasis, and its activity regulates nutrient metabolism and insulin sensitivity. We measured cold-activated lipid landscapes in circulation and in adipose tissue by MS/MSALL shot
Externí odkaz:
https://doaj.org/article/e2d80919fceb41beb08fe7076406da4f
Autor:
Bruna M.S. Silva, Giovanni F. Gomes, Flavio P. Veras, Seppe Cambier, Gabriel V.L. Silva, Andreza U. Quadros, Diego B. Caetité, Daniele C. Nascimento, Camila M.S. Silva, Juliana C. Costa Silva, Samara Damasceno, Ayda H. Schneider, Fabio Beretta, Sabrina S. Batah, Icaro M.S. Castro, Isadora M. Paiva, Tamara Rodrigues, Ana Salina, Ronaldo Martins, Guilherme C. Martelossi Cebinelli, Naira L. Bibo, Daniel Macedo de Melo Jorge, Helder I. Nakaya, Dario S. Zamboni, Luiz O. Leiria, Alexandre T. Fabro, José C. Alves-Filho, Eurico Arruda, Paulo Louzada-Junior, Renê D.R. Oliveira, Larissa D. Cunha, Pierre Van Mol, Lore Vanderbeke, Simon Feys, Els Wauters, Laura Brandolini, Andrea Aramini, Fernando Q. Cunha, Jörg Köhl, Marcello Allegretti, Diether Lambrechts, Joost Wauters, Paul Proost, Thiago M. Cunha
Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that complement component 5a (C5a), through its cellular receptor C5aR1, has pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b1fb8f63bdada259121518f1293a49
https://lirias.kuleuven.be/handle/20.500.12942/719126
https://lirias.kuleuven.be/handle/20.500.12942/719126
Publikováno v:
Trends in Endocrinology & Metabolism. 33:587-599
Owing to its unique capacity to clear macronutrients from circulation and use them to produce heat, thermogenic fat is capable of regulating glucose, lipids, and branched-chain amino acids (BCAA) circulatory levels. At the same time, its activity yie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cec7e41212ddcc83a02d590a86bb050
https://doi.org/10.1016/j.tem.2022.05.003
https://doi.org/10.1016/j.tem.2022.05.003
Autor:
Bruna M. Silva, Flavio P. Veras, Giovanni F. Gomes, Seppe Cambier, Gabriel V. L. Silva, Andreza U. Quadros, Diego B. Caetité, Daniele C. Nascimento, Camilla M. Silva, Juliana C. Silva, Samara Damasceno, Ayda H. Schneider, Fabio Beretta, Sabrina S. Batah, Icaro M. S. Castro, Isadora M. Paiva, Tamara Rodrigues, Ana Salina, Ronaldo Martins, Guilherme C.M. Cebinelli, Naira L. Bibo, Daniel M. Jorge, Helder I. Nakaya, Dario S. Zamboni, Luiz O. Leiria, Alexandre T. Fabro, José C. Alves-Filho, Eurico Arruda, Paulo Louzada-Junior, Renê D. Oliveira, Larissa D. Cunha, Pierre Van Mol, Lore Vanderbeke, Simon Feys, Els Wauters, Laura Brandolini, Fernando Q. Cunha, Jörg Köhl, Marcello Allegretti, Diether Lambrechts, Joost Wauters, Paul Proost, Thiago M. Cunha
Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that complement component 5a (C5a), through its cellular receptor C5aR1, has pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f92d1955374f057b0fde192415d6d085
https://doi.org/10.1101/2022.07.03.498624
https://doi.org/10.1101/2022.07.03.498624
Autor:
Yiming Li, Matthew D. Lynes, Lewis T. Williams, Tim J. Schulz, Steen B. Pedersen, Tian Lian Huang, Niels Jessen, Farnaz Shamsi, Laurie J. Goodyear, Morten Lundh, Matthias Blüher, Srinivas Kothakota, Moosa Mohammadi, Yu-Hua Tseng, Ruidan Xue, Chih-Hao Wang, Pasquale Nigro, Satoru Sugimoto, Brice Emanuelli, Antje Körner, Yang Liu, Luiz O. Leiria, Elena Kempf, Kathrin Landgraf, C. Ronald Kahn, Yvonne Böttcher
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Shamsi, F, Xue, R, Huang, T L, Lundh, M, Liu, Y, Leiria, L O, Lynes, M D, Kempf, E, Wang, C-H, Sugimoto, S, Nigro, P, Landgraf, K, Schulz, T, Li, Y, Emanuelli, B, Kothakota, S, Williams, L T, Jessen, N, Pedersen, S B, Böttcher, Y, Blüher, M, Körner, A, Goodyear, L J, Mohammadi, M, Kahn, C R & Tseng, Y-H 2020, ' FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis ', Nature Communications, vol. 11, no. 1, 1421 . https://doi.org/10.1038/s41467-020-15055-9
Shamsi, F, Xue, R, Huang, T L, Lundh, M, Liu, Y, Leiria, L O, Lynes, M D, Kempf, E, Wang, C H, Sugimoto, S, Nigro, P, Landgraf, K, Schulz, T, Li, Y, Emanuelli, B, Kothakota, S, Williams, L T, Jessen, N, Pedersen, S B, Böttcher, Y, Blüher, M, Körner, A, Goodyear, L J, Mohammadi, M, Kahn, C R & Tseng, Y H 2020, ' FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis ', Nature Communications, vol. 11, no. 1, 1421 . https://doi.org/10.1038/s41467-020-15055-9
Nature Communications
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Shamsi, F, Xue, R, Huang, T L, Lundh, M, Liu, Y, Leiria, L O, Lynes, M D, Kempf, E, Wang, C-H, Sugimoto, S, Nigro, P, Landgraf, K, Schulz, T, Li, Y, Emanuelli, B, Kothakota, S, Williams, L T, Jessen, N, Pedersen, S B, Böttcher, Y, Blüher, M, Körner, A, Goodyear, L J, Mohammadi, M, Kahn, C R & Tseng, Y-H 2020, ' FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis ', Nature Communications, vol. 11, no. 1, 1421 . https://doi.org/10.1038/s41467-020-15055-9
Shamsi, F, Xue, R, Huang, T L, Lundh, M, Liu, Y, Leiria, L O, Lynes, M D, Kempf, E, Wang, C H, Sugimoto, S, Nigro, P, Landgraf, K, Schulz, T, Li, Y, Emanuelli, B, Kothakota, S, Williams, L T, Jessen, N, Pedersen, S B, Böttcher, Y, Blüher, M, Körner, A, Goodyear, L J, Mohammadi, M, Kahn, C R & Tseng, Y H 2020, ' FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis ', Nature Communications, vol. 11, no. 1, 1421 . https://doi.org/10.1038/s41467-020-15055-9
Nature Communications
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Uncoupling protein-1 (UCP1) plays a central role in energy dissipation in brown adipose tissue (BAT). Using high-throughput library screening of secreted peptides, we identify two fibroblast growth factors (FGF), FGF6 and FGF9, as potent inducers of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb9c21dc7ca2f3f0a151ee36d85f6ff
https://doaj.org/article/de377e337a5a402280aaea762fc97cbe
https://doaj.org/article/de377e337a5a402280aaea762fc97cbe
Publikováno v:
Essential Aspects of Immunometabolism in Health and Disease ISBN: 9783030866839
Adipose tissue is composed by adipocytes and stromal-vascular cells that include a wide variety of immune cells. The proportion of these cells in the tissue, their intrinsic characteristics, their degree of differentiation and activation, as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6266bcdafe211cdd331699cd54fc12f7
https://doi.org/10.1007/978-3-030-86684-6_11
https://doi.org/10.1007/978-3-030-86684-6_11
Autor:
Luiz O. Leiria, André Matos de Oliveira, Nayara I. Viana, Sabrina T. Reis, Katia R. M. Leite, William C. Nahas, Alberto A. Antunes, Miguel Srougi, Edilamar Menezes de Oliveira, Fernando F. Fonseca
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Physiological Reports, Vol 9, Iss 7, Pp n/a-n/a (2021)
Physiological Reports
Universidade de São Paulo (USP)
instacron:USP
Physiological Reports, Vol 9, Iss 7, Pp n/a-n/a (2021)
Physiological Reports
Objective To investigate the role of physical activity in functional and molecular bladder alterations in an obese and insulin‐resistant murine model. Methods Wistar rats were randomized into 1. physical activity and standard diet; 2. physical acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3f243f7c54acc6c5a25b4cf48d8433