Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Luiz G, Gardinassi"'
Autor:
Michael N. Yakubu, Victor I. Mwangi, Rebeca L. A. Netto, Maria G. C. Alecrim, Jessica R. S. Alves, Anne C. G. Almeida, Gabriel F. Santos, Gesiane S. Lima, Lucas S. Machado, Hector H. F. Koolen, Tiago P. Guimarães, Andrea R. Chaves, Boniek G. Vaz, Wuelton M. Monteiro, Fabio T. M. Costa, Marcus V. G. Lacerda, Luiz G. Gardinassi, Gisely C. de Melo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Malaria is the leading parasitic disease worldwide, with P. vivax being a major challenge for its control. Several studies have indicated metabolomics as a promising tool for combating the disease. The study evaluated plasma metabolomic prof
Externí odkaz:
https://doaj.org/article/ebfb6b0aff804efc93980cbaba6c5447
Autor:
Victor I. Mwangi, Rebeca L. A. Netto, Mayla G. S. Borba, Gabriel F. Santos, Gesiane S. Lima, Lucas S. Machado, Michael N. Yakubu, Fernando F. A. Val, Vanderson S. Sampaio, Marco A. Sartim, Hector H. F. Koolen, Allyson G. Costa, Maria C. M. Toméi, Tiago P. Guimarães, Andrea R. Chaves, Boniek G. Vaz, Marcus V. G. Lacerda, Wuelton M. Monteiro, Luiz G. Gardinassi, Gisely C. Melo
Publikováno v:
mSystems, Vol 8, Iss 6 (2023)
ABSTRACT Corticosteroids have become a choice for managing severe COVID-19, but the molecular mechanisms behind the response after corticosteroid administration remain incompletely understood. In order to unravel this, comparisons between temporal me
Externí odkaz:
https://doaj.org/article/09c789c98cfa426b9292889737d65fd4
Autor:
Camila O. S. Souza, Jefferson Elias-Oliveira, Marcella R. Pastore, Caroline Fontanari, Vanessa F. Rodrigues, Vanderlei Rodriguez, Luiz G. Gardinassi, Lúcia H. Faccioli
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Schistosomiasis is a neglected tropical disease caused by worms of the genus Schistosoma spp. The progression of disease results in intense tissue fibrosis and high mortality rate. After egg deposition by adult worms, the inflammatory response is cha
Externí odkaz:
https://doaj.org/article/bb3b2f94022d4c6599208d47af569ded
Autor:
Mouzarllem B. Reis, Fernanda L. Rodrigues, Natalia Lautherbach, Alexandre Kanashiro, Carlos A. Sorgi, Alyne F. G. Meirelles, Carlos A. A. Silva, Karina F. Zoccal, Camila O. S. Souza, Simone G. Ramos, Alessandra K. Matsuno, Lenaldo B. Rocha, Helio C. Salgado, Luiz C. C. Navegantes, Ísis C. Kettelhut, Palmira Cupo, Luiz G. Gardinassi, Lúcia H. Faccioli
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Cardiac dysfunction is a major complication that precedes death after scorpion envenomation. Here, authors show that heart failure and mortality are caused by excessive acetylcholine release, which requires IL-1R-dependent PGE2 production. Dexamethas
Externí odkaz:
https://doaj.org/article/3824a55bb5ce42fc8ddfb1f913df0a2a
Autor:
Camila O.S. Souza, Natália Ketelut-Carneiro, Cristiane M. Milanezi, Lúcia H. Faccioli, Luiz G. Gardinassi, João S. Silva
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102548- (2021)
Summary: The recognition of fungi by intracellular NOD-like receptors (NLRs) induces inflammasome assembly and activation. Although the NLRC4 inflammasome has been extensively studied in bacterial infections, its role during fungal infections is uncl
Externí odkaz:
https://doaj.org/article/8c953e87d780462f8f6d2c8bb1180761
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The current pandemic of coronavirus disease 19 (COVID-19) has affected millions of individuals and caused thousands of deaths worldwide. The pathophysiology of the disease is complex and mostly unknown. Therefore, identifying the molecular mechanisms
Externí odkaz:
https://doaj.org/article/6b5932ac848844328aaafaa73637c64b
Autor:
Luiz G. Gardinassi, Myriam Arévalo-Herrera, Sócrates Herrera, Regina J. Cordy, ViLinh Tran, Matthew R. Smith, Michelle S. Johnson, Balu Chacko, Ken H. Liu, Victor M. Darley-Usmar, Young-Mi Go, Dean P. Jones, Mary R. Galinski, Shuzhao Li
Publikováno v:
Redox Biology, Vol 17, Iss , Pp 158-170 (2018)
Almost invariably, humans become ill during primary infections with malaria parasites which is a pathology associated with oxidative stress and perturbations in metabolism. Importantly, repetitive exposure to Plasmodium results in asymptomatic infect
Externí odkaz:
https://doaj.org/article/5768d83a0a9a4257af14d0af86dd80cf
Publikováno v:
Future Microbiology. 18:245-247
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed1ba6bc5a0a4bbb511157526911d289
https://doi.org/10.2217/fmb-2022-0261
https://doi.org/10.2217/fmb-2022-0261
Autor:
Sandra R. Maruyama, Gustavo R. Garcia, Felipe R. Teixeira, Lucinda G. Brandão, Jennifer M. Anderson, José M. C. Ribeiro, Jesus G. Valenzuela, Jana Horackova, Cecília J. Veríssimo, Luciana M. Katiki, Tamy M. Banin, Amanda F. Zangirolamo, Luiz G. Gardinassi, Beatriz R. Ferreira, Isabel K. F. de Miranda-Santos
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-16 (2017)
Abstract Background Ticks cause massive damage to livestock and vaccines are one sustainable substitute for the acaricides currently heavily used to control infestations. To guide antigen discovery for a vaccine that targets the gamut of parasitic st
Externí odkaz:
https://doaj.org/article/cd2a60e06d8c4185bdce29e1359ffcb4
Autor:
Karina F. Zoccal, Luiz G. Gardinassi, Karla C. F. Bordon, Eliane C. Arantes, Sylvie Marleau, Huy Ong, Lúcia H. Faccioli
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Over 1 million cases of scorpion stings are estimated every year, whereas current treatment is limited to antivenom serum combined with supportive therapy. Tityus serrulatus scorpion venom (TsV) is composed of diverse molecules, including toxins that
Externí odkaz:
https://doaj.org/article/51d187fa6211407a92e65c8a6d1a5ab0