Výsledky vyhledávání - "Luiz Felipe G. Sanson"

Stew in its Own Juice: Protein Homeostasis Machinery Inhibition Reduces Cell Viability in Multiple Myeloma Cell Lines

Autor: Angela Isabel Pereira Eugênio, Gisele W. B. Colleoni, Luiz Felipe G. Sanson, Mariana Bleker de Oliveira, Rebecca S S Barbosa-Dantas

Publikováno v: Current Molecular Medicine. 19:112-119

Introduction:Multiple myeloma (MM) cells accumulate in the bone marrow and produce enormous quantities of immunoglobulins, causing endoplasmatic reticulum stress and activation of protein handling machinery, such as heat shock protein response, autop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c681aaa6629d102f70ff9e70128434
https://doi.org/10.2174/1566524019666190305134441

Zobrazit plný text záznamu

Anti-myeloma effects of ruxolitinib combined with bortezomib and lenalidomide: A rationale for JAK/STAT pathway inhibition in myeloma patients

Autor: Faith E. Davies, Veruska L. Fook-Alves, Gisele W. B. Colleoni, Luiz Felipe G. Sanson, Mariana Bleker de Oliveira, Walter Moises Tobias Braga, Angela Isabel Pereira Eugênio, Mariana F. de Carvalho, Rodrigo Carlini Fernando

Publikováno v: Cancer letters. 403

JAK proteins have been linked with survival and proliferation of multiple myeloma (MM) cells; therefore, JAK inhibition could be a therapeutic strategy for MM. We evaluated JAK1 and JAK2 expression in MM patients and the effects of JAK/STAT pathway i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200552994404e01d120cad7eddc69b63
https://pubmed.ncbi.nlm.nih.gov/28645562

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání