In vitro-induction of metronidazole-resistant Giardia duodenalis is not associated with nucleotide alterations in the genes involved in pro-drug activation

Autor: Luiz Antonio Pimentel Lopes-Oliveira, Maria Fantinatti, Alda Maria Da-Cruz

Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 115 (2020)

Giardiasis is an infectious disease caused by Giardia duodenalis. The pro-drug metronidazole (MTZ) is the first-line treatment for giardiasis. Parasite’s proteins as pyruvate:ferredoxin oxidoreductase (PFOR), ferredoxin (Fd), nitroreductase-1 (NR-1

Externí odkaz: https://doaj.org/article/95a5d37e04d64008a3130cdfd32e1d25

Epidemiology of Giardia duodenalis assemblages in Brazil: there is still a long way to go

Autor: Alda Maria Da-Cruz, Maria Fantinatti, Luiz Antonio Pimentel Lopes-Oliveira, Monique Gonçalves-Pinto

Publikováno v: Memórias do Instituto Oswaldo Cruz, Volume: 115, Article number: e200431, Published: 25 JAN 2021
Memórias do Instituto Oswaldo Cruz
Memórias do Instituto Oswaldo Cruz., Vol 115 (2021)

Giardia duodenalis infection is distributed worldwide and can achieve prevalence around 60%, especially in developing countries. This protozoan is divided into eight assemblages, in which A and B have high zoonotic potential, whereas C to H are host-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda289a23ea3fc3484fd7f1e92d4330f
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