Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Luiz A. Marconcini"'
Autor:
Steven D. Shapiro, Heather E. Metz, Alyssa D. Gregory, Kwok K. Wong, Corrine R. Kliment, Luiz A. Marconcini, Hongbin Ji, Stuart J. Frank, Donna B. Stolz, Kimberly M. Jenkins, A. McGarry Houghton, Majd Mouded, Eduardo E. Egea, Danuta M Rzymkiewicz, Keith A Beaulieu, Stephanie R. Land
Publikováno v:
Nature medicine
Lung cancer is the leading cause of cancer death worldwide. Recent data suggest that tumor-associated inflammatory cells may modify lung tumor growth and invasiveness. To determine the role of neutrophil elastase (encoded by Elane) on tumor progressi
Autor:
David L. Perkins, Robert P. Mecham, Luiz A. Marconcini, Pablo A. Quintero, Steven D. Shapiro, Diane G. Kelley, Robert M. Senior, A. McGarry Houghton, Dale K. Kobayashi
Publikováno v:
Journal of Clinical Investigation. 116:753-759
Mice lacking macrophage elastase (matrix metalloproteinase-12, or MMP-12) were previously shown to be protected from the development of cigarette smoke-induced emphysema and from the accumulation of lung macrophages normally induced by chronic exposu
Autor:
David J. Sugarbaker, Thomas J. Mariani, A. M. Houghton, N. El-Bardeesy, Giovanni Tonon, Aram F. Hezel, Luiz A. Marconcini, Richard S. Maser, Hongbin Ji, Steven D. Shapiro, Kwok-Kin Wong, Roderick T. Bronson, Robert F. Padera, Kate McNamara, C. B. Kim, Samanthi A. Perera
Publikováno v:
Oncogene. 25(14)
Activating mutations in K-ras are one of the most common genetic alterations in human lung cancer. To dissect the role of K-ras activation in bronchial epithelial cells during lung tumorigenesis, we created a model of lung adenocarcinoma by generatin