Výsledky vyhledávání - "Luisina I Onofrio"

Akademický článek

Trypanosoma cruzi infection is a potent risk factor for non-alcoholic steatohepatitis enhancing local and systemic inflammation associated with strong oxidative stress and metabolic disorders.

Autor: Luisina I Onofrio, Alfredo R Arocena, Augusto F Paroli, María E Cabalén, Marta C Andrada, Roxana C Cano, Susana Gea

Publikováno v: PLoS Neglected Tropical Diseases, Vol 9, Iss 2, p e0003464 (2015)

BACKGROUND:The immune mechanisms underlying experimental non-alcoholic steatohepatitis (NASH), and more interestingly, the effect of T. cruzi chronic infection on the pathogenesis of this metabolic disorder are not completely understood. METHODOLOGY/

Externí odkaz: https://doaj.org/article/1d392c7a0b634562bf05ba9b9e6d212d

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Akademický článek

Dynamics of circulating follicular helper T cell subsets and follicular regulatory T cells in rheumatoid arthritis patients according to HLA-DRB1 locus

Autor: Paola V. Ferrero, Luisina I. Onofrio, Cristina del Valle Acosta, Estefania R. Zacca, Nicolas E. Ponce, Eduardo Mussano, Laura B. Onetti, Ignacio I. Cadile, Alicia B. Costantino, Marina L. Werner, Luciana A. Mas, Teresita Alvarellos, Carolina L. Montes, Eva V. Acosta Rodríguez, Adriana Gruppi

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

B cells, follicular helper T (Tfh) cells and follicular regulatory T (Tfr) cells are part of a circuit that may play a role in the development or progression of rheumatoid arthritis (RA). With the aim of providing further insight into this topic, her

Externí odkaz: https://doaj.org/article/25951df10705478b9cb0f1559b93534f

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Tofacitinib treatment of Rheumatoid Arthritis: Increases senescent T‐cell frequency in patients and limits T‐cell function in vitro

Autor: Vanina A. Alamino, Luisina I. Onofrio, Cristina del Valle Acosta, Paola V. Ferrero, Estefanía R. Zacca, Isaac I. Cadile, Eduardo D. Mussano, Laura B. Onetti, Carolina L. Montes, Adriana Gruppi, Eva V. Acosta Rodriguez

Publikováno v: European Journal of Immunology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41f7a71f4e3a09ed2e6f73ab29b424a8
https://doi.org/10.1002/eji.202250353

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Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model

Autor: María Fernanda Cabral, Liliana Maria Sanmarco, Nicolás Eric Ponce, María Eugenia Cabalén, Susana Gea, Marta Cecilia Andrada, Roxana Carolina Cano, Maria del Pilar Aoki, Luisina I. Onofrio

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Oncotarget

Chronic obesity and Chagas disease (caused by the protozoan Trypanosoma cruzi) represent serious public health concerns. The interrelation between parasite infection, adipose tissue, immune system and metabolism in an obesogenic context, has not been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e814d97703c5d0aba910935bc5342df
https://doi.org/10.18632/oncotarget.7630

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Akademický článek

PD-L1+ Regulatory B Cells Are Significantly Decreased in Rheumatoid Arthritis Patients and Increase After Successful Treatment

Autor: Estefanía R. Zacca, Luisina I. Onofrio, Cristina D. V. Acosta, Paola V. Ferrero, Sergio M. Alonso, María C. Ramello, Eduardo Mussano, Laura Onetti, Isaac I. Cadile, Maria I. Stancich, Maria C. Taboada Bonfanti, Carolina L. Montes, Eva V. Acosta Rodríguez, Adriana Gruppi

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Background: B cells play an important role in the development and maintenance of rheumatoid arthritis (RA). Although IL-10–producing B cells represent a major subset of regulatory B cells (Bregs) able to suppress autoimmune and inflammatory respons

Externí odkaz: https://doaj.org/article/e65f2c17fb034e15bcbdda3f877c4dc3

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Akademický článek

NLRP3 Inflammasome and Caspase-1/11 Pathway Orchestrate Different Outcomes in the Host Protection Against Trypanosoma cruzi Acute Infection

Autor: Augusto F. Paroli, Patricia V. Gonzalez, Cintia Díaz-Luján, Luisina I. Onofrio, Alfredo Arocena, Roxana C. Cano, Eugenio A. Carrera-Silva, Susana Gea

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Infection with protozoan parasite Trypanosoma cruzi results in activation of nucleotide-binding domain and leucine-rich repeat containing receptors (NLRs). NLR activation leads to inflammasome formation, the activation of caspase-1, and the subsequen

Externí odkaz: https://doaj.org/article/f79a4acb1eb346dc84321152cd1482d3

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