Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Luise U Weigand"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/05234a9571e04476ab941c9e309bf845
Autor:
Jane Harper, Katherine J Adams, Giovanna Bossi, Debbie E Wright, Andrea R Stacey, Nicole Bedke, Ruth Martinez-Hague, Dan Blat, Laure Humbert, Hazel Buchanan, Gabrielle S Le Provost, Zoe Donnellan, Ricardo J Carreira, Samantha J Paston, Luise U Weigand, Martina Canestraro, Joseph P Sanderson, Sophie Botta Gordon-Smith, Kate L Lowe, Karolina A Rygiel, Alex S Powlesland, Annelise Vuidepot, Namir J Hassan, Brian J Cameron, Bent K Jakobsen, Joseph Dukes
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205491 (2018)
Robust preclinical testing is essential to predict clinical safety and efficacy and provide data to determine safe dose for first-in-man studies. There are a growing number of examples where the preclinical development of drugs failed to adequately p
Externí odkaz:
https://doaj.org/article/c3d7165394b5442098ed39f7073a5fbd
Autor:
Angela M. Krackhardt, Luise U. Weigand, Lena Allweiss, Karin Wisskirchen, K. Metzger, Tassilo Volz, J Kah, Ulrike Protzer, Maura Dandri, Antje Malo, Matthias Schiemann
Publikováno v:
Zeitschrift für Gastroenterologie. 56:E2-E89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f46caafd6566be36d955ef2df1b50a57
https://doi.org/10.1055/s-0037-1612843
https://doi.org/10.1055/s-0037-1612843
Autor:
Debbie E. Wright, Bent K. Jakobsen, Tomasz Dobrzycki, Ruth Martinez-Hague, Luise U. Weigand, Ana Ribeiro, Nicole Bedke, Jane Harper, Sophie Botta Gordon-Smith, Samantha Paston, Laure Humbert, Dan Blat, Joseph Dukes, Andrea Stacey, Giovanna Bossi, Zoe Donellan, Martina Canestraro
Publikováno v:
Cancer Immunology Research. 7:A214-A214
Immune Mobilising Monoclonal TCRs Against Cancer (ImmTAC) molecules are a new class of bi-specific biologic specifically designed to recognize and eradicate cancer cells. ImmTAC molecules are composed of an affinity-enhanced T-cell receptor (TCR) fus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81fc78f248c4e5df91924dae9529c039
https://doi.org/10.1158/2326-6074.cricimteatiaacr18-a214
https://doi.org/10.1158/2326-6074.cricimteatiaacr18-a214
Autor:
Katharina Götze, Xiaoling Liang, Josef Mautner, Oliver J. Stötzer, Angela M. Krackhardt, Christian Peschel, Luise U. Weigand, Christoph Salat, Sabine Schmied, Sabine Mall, Richard Klar
Publikováno v:
Immunology 137, 226-238 (2012)
Adoptive transfer of T cells genetically modified with tumour-specific T-cell receptors (TCR) is a promising novel approach in the treatment of cancer. We have previously isolated an allorestricted MHC class I-restricted TCR with specificity for Form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0b6f70680f02cda7af025161efd33b
https://doi.org/10.1111/imm.12000
https://doi.org/10.1111/imm.12000
Autor:
Karin Wisskirchen, Angela M. Krackhardt, Maura Dandri, Tassilo Volz, Luise U. Weigand, Ulrike Protzer, Wolfgang Uckert, K. Metzger, Matthias Schiemann, J Kah
Publikováno v:
Journal of Hepatology. 66:S29-S30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad16c1d3ee34b2d63c8643d8f119c41e
https://doi.org/10.1016/s0168-8278(17)30322-7
https://doi.org/10.1016/s0168-8278(17)30322-7
Autor:
Emma Hickman, Luise U. Weigand, Debbie Baker, Linda Hibbert, Annelise Vuidepot, Namir J. Hassan, Zoe Donnellan, Samantha Paston, Louise Conlon, Giovanna Bossi, Joseph Dukes, Ruth Simmons, Ruth Ryan, Caroline Boudousquie, Alex Powlesland, Vanessa L. Clark, Bent K. Jakobsen, Kathy Hale
Publikováno v:
Journal for Immunotherapy of Cancer
Meeting abstracts Malignant cells may be recognised by T cells binding cell surface Class I HLA (Human Leukocyte Antigen)-peptide complexes presenting disease-associated epitopes. Many cancer patients have been shown to generate CD8 cytotoxic T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40a79b68a41a341e39f5c9a1e1daf7d
https://doi.org/10.1186/2051-1426-3-s2-p380
https://doi.org/10.1186/2051-1426-3-s2-p380
Autor:
Karin Wisskirchen, Ulrike Protzer, Luise U. Weigand, Martin F. Sprinzl, Angela M. Krackhardt, K. Metzger, Wolfgang Uckert, Elisa Kieback, Dirk H. Busch
Publikováno v:
Cytotherapy. 18:S15-S16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb4d0ea0f41296677cbac2081606795d
https://doi.org/10.1016/j.jcyt.2016.03.041
https://doi.org/10.1016/j.jcyt.2016.03.041
Autor:
Luise U. Weigand, Johanne M. Pentier, Martina Canestraro, Mary Connolly, Bent K. Jakobsen, Ruth Ryan, Annelise Vuidepot, Namir J. Hassan
Publikováno v:
Cancer Immunology Research. 4:A037-A037
For years cancer therapies were mainly concentrated around surgery, chemotherapy and radiotherapy. Recently, a new domain has emerged. Immunotherapies aim to exploit, enhance and optimise the patient's immune system to be more potent at eradicating t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::346246e98175e287e9fbcde6430ba6cf
https://doi.org/10.1158/2326-6074.cricimteatiaacr15-a037
https://doi.org/10.1158/2326-6074.cricimteatiaacr15-a037
Autor:
Luise U. Weigand, Andreas Moosmann, Daniel Sommermeyer, Joachim W. Ellwart, Xiaoling Liang, Andrea Schub, Yanyan Han, Angela M. Krackhardt, Judith C. van der Griendt, Matthias Leisegang, Ingrid G. Schuster, Florian Anderl, Christian Peschel, Dirk H. Busch, Wolfgang Uckert, Elfriede Eppinger
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(3)
T cells can recognize tumor cells specifically by their TCR and the transfer of TCR-engineered T cells is a promising novel tool in anticancer therapies. We isolated and characterized four allorestricted TCRs with specificity for the HER2/neu-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbef0be05e29137a7e8a39fe47b61c6a
https://pubmed.ncbi.nlm.nih.gov/20042572
https://pubmed.ncbi.nlm.nih.gov/20042572