Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Luise Fuhr"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9130 (2022)
The circadian clock generates 24 h rhythms in behavioural, cellular and molecular processes. Malfunctions of the clock are associated with enhanced susceptibility to cancer, worse treatment response and poor prognosis. Clock-controlled genes are invo
Externí odkaz:
https://doaj.org/article/3549ad85057e4aad9eae4b40517426b4
Autor:
Luise Fuhr, Rukeia El-Athman, Rosella Scrima, Olga Cela, Annalucia Carbone, Henning Knoop, Yin Li, Karen Hoffmann, Mikko O. Laukkanen, Francesco Corcione, Ralf Steuer, Thomas F. Meyer, Gianluigi Mazzoccoli, Nazzareno Capitanio, Angela Relógio
Publikováno v:
EBioMedicine, Vol 33, Iss , Pp 105-121 (2018)
An endogenous molecular clockwork drives various cellular pathways including metabolism and the cell cycle. Its dysregulation is able to prompt pathological phenotypes including cancer. Besides dramatic metabolic alterations, cancer cells display sev
Externí odkaz:
https://doaj.org/article/ef1dbb151a5a449aa1c455cb4bcb8751
Publikováno v:
EBioMedicine, Vol 33, Iss , Pp 68-81 (2018)
Accumulating evidence points to a significant role of the circadian clock in the regulation of splicing in various organisms, including mammals. Both dysregulated circadian rhythms and aberrant pre-mRNA splicing are frequently implicated in human dis
Externí odkaz:
https://doaj.org/article/8ec81f668bbb4668b336db3f8fc00836
Autor:
Annabell Plauth, Anne Geikowski, Susanne Cichon, Sylvia J. Wowro, Linda Liedgens, Morten Rousseau, Christopher Weidner, Luise Fuhr, Magdalena Kliem, Gail Jenkins, Silvina Lotito, Linda J. Wainwright, Sascha Sauer
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 433-437 (2016)
We show here if under physiologically relevant conditions resveratrol (RSV) remains stable or not. We further show under which circumstances various oxidation products of RSV such as ROS can be produced. For example, in addition to the widely known e
Externí odkaz:
https://doaj.org/article/76504a6b8f29466a9f6895f328d328dc
Autor:
Rukeia El-Athman, Nikolai N Genov, Jeannine Mazuch, Kaiyang Zhang, Yong Yu, Luise Fuhr, Mónica Abreu, Yin Li, Thomas Wallach, Achim Kramer, Clemens A Schmitt, Angela Relógio
Publikováno v:
PLoS Biology, Vol 15, Iss 12, p e2002940 (2017)
The mammalian circadian clock and the cell cycle are two major biological oscillators whose coupling influences cell fate decisions. In the present study, we use a model-driven experimental approach to investigate the interplay between clock and cell
Externí odkaz:
https://doaj.org/article/3212cfffbec545959ab30ba2cb95d966
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 13, Iss C, Pp 417-426 (2015)
The circadian clock is a powerful endogenous timing system, which allows organisms to fine-tune their physiology and behaviour to the geophysical time. The interplay of a distinct set of core-clock genes and proteins generates oscillations in express
Externí odkaz:
https://doaj.org/article/1992a544fc83449190f8a09bee75388a
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 16, p 3977 (2019)
Mounting evidence points to a role of the circadian clock in the temporal regulation of post-transcriptional processes in mammals, including alternative splicing (AS). In this study, we carried out a computational analysis of circadian and ultradian
Externí odkaz:
https://doaj.org/article/0428e35cd5fb4b02a19ab005616e5926
Autor:
Robert Lehmann, Liam Childs, Philippe Thomas, Monica Abreu, Luise Fuhr, Hanspeter Herzel, Ulf Leser, Angela Relógio
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126283 (2015)
By regulating the timing of cellular processes, the circadian clock provides a way to adapt physiology and behaviour to the geophysical time. In mammals, a light-entrainable master clock located in the suprachiasmatic nucleus (SCN) controls periphera
Externí odkaz:
https://doaj.org/article/3fa917f5b28c4aca8ddda8aea820dcf9
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9130
The circadian clock generates 24 h rhythms in behavioural, cellular and molecular processes. Malfunctions of the clock are associated with enhanced susceptibility to cancer, worse treatment response and poor prognosis. Clock-controlled genes are invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::77142b7b27d50f5b54ec0f1cce6d1eca
Autor:
Sylvia J. Wowro, Magdalena Kliem, Annabell Plauth, Susanne Cichon, Silvina Lotito, Anne Geikowski, Sascha Sauer, Luise Fuhr, Linda Liedgens, Linda Jane Wainwright, Morten Rousseau, Gail Jenkins, Christopher Weidner
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 433-437 (2016)
Data in Brief
Data in Brief
We show here if under physiologically relevant conditions resveratrol (RSV) remains stable or not. We further show under which circumstances various oxidation products of RSV such as ROS can be produced. For example, in addition to the widely known e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa34d1e036bd5320ea585e342f1448ab