Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Luise Appeltshauser"'
Autor:
Luise Appeltshauser, Helena Glenewinkel, Sophia Rohrbacher, Lena Wessely, Carmen Villmann, Claudia Sommer, Kathrin Doppler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAutoimmune nodopathy (AN) is a new entity in the field of peripheral neuropathies and is defined by the presence of auto-antibodies against structures of the node of Ranvier combined with specific clinico-pathophysiological features and t
Externí odkaz:
https://doaj.org/article/0f3eac386b1e4fe9ba19258c1ec1c537
Autor:
Katharina Hecker, Julia Grüner, Beate Hartmannsberger, Luise Appeltshauser, Carmen Villmann, Claudia Sommer, Kathrin Doppler
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIgG4 autoantibodies against paranodal proteins are known to induce acute-onset and often severe sensorimotor autoimmune neuropathies. How autoantibodies reach their antigens at the paranode in spite of the myelin barrier is still unclear.
Externí odkaz:
https://doaj.org/article/db85d9041e4f49c2b593d72ad4cefaa3
Autor:
Luise Appeltshauser, Janis Linke, Hannah S. Heil, Christine Karus, Joachim Schenk, Katherina Hemmen, Claudia Sommer, Kathrin Doppler, Katrin G. Heinze
Publikováno v:
Neurobiology of Disease, Vol 182, Iss , Pp 106139- (2023)
The node of Ranvier is the key element in saltatory conduction along myelinated axons, but its specific protein organization remains elusive in the human species. To shed light on nanoscale anatomy of the human node of Ranvier in health and disease,
Externí odkaz:
https://doaj.org/article/aad97c224a4a48d0aea422e54e0ff252
Autor:
Kathrin Doppler, Yasmin Schuster, Luise Appeltshauser, Lydia Biko, Carmen Villmann, Andreas Weishaupt, Christian Werner, Claudia Sommer
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Abstract Background Autoantibodies against the paranodal protein contactin-1 have recently been described in patients with severe acute-onset autoimmune neuropathies and mainly belong to the IgG4 subclass that does not activate complement. IgG3 anti-
Externí odkaz:
https://doaj.org/article/7e1e9ef7125243c4bd750998efa90d4e
Autor:
Kathrin Doppler, Luise Appeltshauser, Heidrun H Krämer, Judy King Man Ng, Edgar Meinl, Carmen Villmann, Peter Brophy, Sulayman D Dib-Hajj, Stephen G Waxman, Andreas Weishaupt, Claudia Sommer
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134274 (2015)
Multifocal motor neuropathy is an immune mediated disease presenting with multifocal muscle weakness and conduction block. IgM auto-antibodies against the ganglioside GM1 are detectable in about 50% of the patients. Auto-antibodies against the parano
Externí odkaz:
https://doaj.org/article/5ee8bbd5996d4f549a439c1497ae70a0
Autor:
Kathrin Doppler, Luise Appeltshauser, Heidrun H Krämer, Judy King Man Ng, Edgar Meinl, Carmen Villmann, Peter Brophy, Sulayman D Dib-Hajj, Stephen G Waxman, Andreas Weishaupt, Claudia Sommer
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0137443 (2015)
Externí odkaz:
https://doaj.org/article/8f2df1c727f948689e54d1f118fdf221
Autor:
Luise Appeltshauser, Helena Junghof, Julia Messinger, Janis Linke, Axel Haarmann, Ilya Ayzenberg, Panoraia Baka, Johannes Dorst, Anna L Fisse, Thomas Grüter, Valerie Hauschildt, Alexander Jörk, Frank Leypoldt, Mathias Mäurer, Edgar Meinl, Sebastian Michels, Jeremias Motte, Kalliopi Pitarokoili, Mark Stettner, Carmen Villmann, Marc Weihrauch, Gabriel S Welte, Inga Zerr, Katrin G Heinze, Claudia Sommer, Kathrin Doppler
Publikováno v:
Brain 146(5), 1932-1949 (2023). doi:10.1093/brain/awac418
Autoimmune neuropathy associated with antibodies against pan-neurofascin is a new subtype of nodo-paranodopathy. It is relevant because it is associated with high morbidity and mortality. Affected patients often require intensive care unit treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871ab7f2276a8783a61e40a5c42da629
https://doi.org/10.1093/brain/awac418
https://doi.org/10.1093/brain/awac418
Autor:
Kathrin Doppler, Thomas G. K. Breuer, Ilya Ayzenberg, Kalliopi Pitarokoili, Ralf Gold, Carolin Schwake, Claudia Sommer, Katharina Starz, Martin Grond, Thomas Grüter, Kathy Keyvani, Luise Appeltshauser, Jeremias Motte, Marie Spenner, Anna Lena Fisse, Adnan Labedi, Christiane Schneider-Gold, David Heinrich, Diamantis Athanasopoulos, Miriam Fels
Publikováno v:
Journal of the Peripheral Nervous System. 26:475-480
Inflammatory neuropathies with pathogenic involvement of the nodes of Ranvier through autoantibodies have been increasingly characterized in the past years. The so-called anti-pan-NF-associated neuropathies caused by the simultaneous existence of ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a6dd6317a38a9d75b53cea3dda8a11
https://doi.org/10.1111/jns.12465
https://doi.org/10.1111/jns.12465
Autor:
Luise Appeltshauser, Janis Linke, Hannah S. Heil, Christine Karus, Joachim Schenk, Katherina Hemmen, Claudia Sommer, Kathrin Doppler, Katrin G. Heinze
To shed light on nanoscale pathologies in patients with polyneuropathy, we assessed human nerve biopsies by super-resolution fluorescence microscopy. We focused on both physiological protein arrangement and pathological ultrastructural changes at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::943e39b1e03845ccfef8e6d1942d2423
https://doi.org/10.1101/2022.08.05.22278366
https://doi.org/10.1101/2022.08.05.22278366
Autor:
Kathrin Doppler, Luise Appeltshauser
Publikováno v:
NeuroTransmitter. 30:52-65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05ce72ca4121487879369151d51f6e19
https://doi.org/10.1007/s15016-019-6600-4
https://doi.org/10.1007/s15016-019-6600-4