Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Luise Apelt"'
Autor:
Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 3, Pp 1-14 (2015)
Abstract Post‐translational protein modifications, such as tyrosine phosphorylation, regulate protein–protein interactions (PPIs) critical for signal processing and cellular phenotypes. We extended an established yeast two‐hybrid system employi
Externí odkaz:
https://doaj.org/article/5064d016645c4e3bb83d8ffde1df14a5
Autor:
Hui-Ting Chou, Luise Apelt, Daniel P. Farrell, Susan Roehl White, Jonathan Woodsmith, Vladimir Svetlov, Jaclyn S. Goldstein, Andrew R. Nager, Zixuan Li, Jean Muller, Hélène Dollfus, Evgeny Nudler, Ulrich Stelzl, Frank DiMaio, Thomas Walz, Maxence V. Nachury
representative structures of all domain models that were used when modeling the domains of the BBsome. Structures are built using Rosetta abinitio, or Rosetta CM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::015870f3ac42d73d9d9aecf23ab2b47e
Autor:
Ulrich Stelzl, Karine F. Santos, Luise Apelt, Leonie Rosenberger, Markus C. Wahl, Christian Becke, Eva Absmeier
Publikováno v:
Acta Crystallographica Section D-Biological Crystallography
The spliceosomal RNA helicase Brr2 is required for the assembly of a catalytically active spliceosome on a messenger RNA precursor. Brr2 exhibits an unusual organization with tandem helicase units, each comprising dual RecA-like domains and a Sec63 h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65256bccbc2b6bd88b2236fc6113b2c6
https://doi.org/10.1107/s1399004715001005
https://doi.org/10.1107/s1399004715001005
Autor:
Ulrich Stelzl, Bernd Timmermann, Luise Apelt, Victoria Casado-Medrano, Jonathan Woodsmith, Ziya Özkan
Publikováno v:
Nature methods
The identification of genomic variants in healthy and diseased individuals continues to rapidly outpace our ability to functionally annotate these variants. Techniques that both systematically assay the functional consequences of nucleotide-resolutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6640ed1da1e33449ac324356440832c0
https://pubmed.ncbi.nlm.nih.gov/29039417
https://pubmed.ncbi.nlm.nih.gov/29039417
Autor:
Evgeny Nudler, Vladimir Svetlov, Hélène Dollfus, Ulrich Stelzl, Thomas Walz, Daniel P. Farrell, Susan Roehl White, Jonathan Woodsmith, Luise Apelt, Frank DiMaio, Jaclyn S. Goldstein, Jean Muller, Zixuan Li, Maxence V. Nachury, Andrew R. Nager, Hui-Ting Chou
Publikováno v:
Structure
The unique membrane composition of cilia is maintained by a diffusion barrier at the transition zone that is breached when the BBSome escorts signaling receptors out of cilia. Understanding how the BBSome removes proteins from cilia has been hampered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b86b96f4b7e069376bd70d1ba6c0a2
https://doi.org/10.1016/j.str.2019.06.006
https://doi.org/10.1016/j.str.2019.06.006
Autor:
Kevin E. Knockenhauer, Luise Apelt, Thomas U. Schwartz, Nouhad Benlasfer, Nina C. Leksa, Ulrich Stelzl
Publikováno v:
Molecular and Cellular Proteomics
The nuclear pore complex (NPC) enables transport across the nuclear envelope. It is one of the largest multiprotein assemblies in the cell, built from about 30 proteins called nucleoporins (Nups), organized into distinct subcomplexes. Structure deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6aa0e06957a84b08b87ab86cb58cdc
https://europepmc.org/articles/PMC4974338/
https://europepmc.org/articles/PMC4974338/
Autor:
Cindy L. Will, Luise Apelt, Markus C. Wahl, Alexander K.C. Ulrich, Tonio Schütze, N Bartlick, Reinhard Lührmann, M Seeger, Ulrich Stelzl, Gert Weber
Publikováno v:
RNA
Spliceosomal Prp38 proteins contain a conserved amino-terminal domain, but only higher eukaryotic orthologs also harbor a carboxy-terminal RS domain, a hallmark of splicing regulatory SR proteins. We show by crystal structure analysis that the amino-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e14fabb1b7f31271541c88972e401e
https://europepmc.org/articles/PMC4712676/
https://europepmc.org/articles/PMC4712676/
Autor:
Bernhard Ehlers, Christoph Bührer, Jörg Hofmann, Katharina Weizsaecker, Detlev H. Krüger, Susanne E. Kampmann, Lars Garten, Birgit Schindele, Luise Apelt
Publikováno v:
Medical Microbiology and Immunology. 200:109-113
Prenatally acquired human cytomegalovirus (HCMV) infection is the most frequent viral infection of newborns in developed countries. Virostatic therapy is accompanied by side effects and stepwise emergence of resistant virus variants. Different genoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897b441bbd7204f4bd2886e327ffaac1
https://doi.org/10.1007/s00430-010-0181-y
https://doi.org/10.1007/s00430-010-0181-y
Autor:
Bernhard Ehlers, Birgit Schindele, Thomas Mertens, Andreas Nitsche, Jörg Hofmann, Sebastian Voigt, Luise Apelt, Detlef Michel
Ganciclovir (GCV) resistance frequently occurs upon prolonged treatment of ongoing active human cytomegalovirus (HCMV) infection in individuals with immature or compromised immune functions (e.g., recipients of solid-organ and hematopoietic stem cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f72690ee2f62730c1b55d71e46e749
https://europepmc.org/articles/PMC2981242/
https://europepmc.org/articles/PMC2981242/