Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Luisa Vonghia"'
Autor:
Jonathan Mertens, Jonas Weyler, Eveline Dirinck, Luisa Vonghia, Wilhelmus J. Kwanten, Laura Mortelmans, Cedric Peleman, Shivani Chotkoe, Maarten Spinhoven, Floris Vanhevel, Luc F. Van Gaal, Benedicte Y. De Winter, Christophe E.M. De Block, Sven M. Francque
Publikováno v:
JHEP Reports, Vol 5, Iss 7, Pp 100753- (2023)
Background & Aims: The epidemiology of non-alcoholic fatty liver disease (NAFLD) in people with type 1 diabetes (T1D) is not yet elucidated. This study aimed to assess the diagnostic accuracy of non-invasive tests for NAFLD, to investigate the preval
Externí odkaz:
https://doaj.org/article/1e1215ad4ad1428687e67109a0adbf59
Autor:
Mikhaïl A. Van Herck, Luisa Vonghia, Wilhelmus J. Kwanten, Yvon Julé, Thomas Vanwolleghem, Didier G. Ebo, Peter P. Michielsen, Joris G. De Man, Lucio Gama, Benedicte Y. De Winter, Sven M. Francque
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 3, Pp 467-490 (2020)
Background & Aims: Nonalcoholic steatohepatitis (NASH) is a multisystem condition, implicating liver and adipose tissue. Although the general involvement of the innate and adaptive immune system has been established, we aimed to define the exact role
Externí odkaz:
https://doaj.org/article/4e44727ed95a41d9b6a985c3cf095b2d
Autor:
Denise van der Graaff, Shivani Chotkoe, Benedicte De Winter, Joris De Man, Christophe Casteleyn, Jean-Pierre Timmermans, Isabel Pintelon, Luisa Vonghia, Wilhelmus J. Kwanten, Sven Francque
Publikováno v:
JHEP Reports, Vol 4, Iss 2, Pp 100412- (2022)
Background & Aims: Intrahepatic vascular resistance is increased in early non-alcoholic fatty liver disease (NAFLD), potentially leading to tissue hypoxia and triggering disease progression. Hepatic vascular hyperreactivity to vasoconstrictors has be
Externí odkaz:
https://doaj.org/article/bfe0445a0c4649978d4f67fe3a777634
Autor:
Mikhaïl A. Van Herck, Luisa Vonghia, Wilhelmus J. Kwanten, Thomas Vanwolleghem, Didier G. Ebo, Peter P. Michielsen, Joris G. De Man, Lucio Gama, Benedicte Y. De Winter, Sven M. Francque
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background and Aims: Non-alcoholic steatohepatitis (NASH) is a multisystem condition, involving the liver, adipose tissue, and immune system. Regulatory T (Treg) cells are a subset of T cells that exert an immune-controlling effect. Previously, a red
Externí odkaz:
https://doaj.org/article/383d9d93078d478c90cc23017e4504ff
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Non-alcoholic fatty liver disease (NAFLD) and Alcoholic Liver Disease (ALD) are major causes of liver-related morbidity and mortality and constitute important causes of liver transplantation. The spectrum of the liver disease is wide and includes iso
Externí odkaz:
https://doaj.org/article/ab5f5ad1062946c6946c1f69467606b1
Autor:
Mikhaïl A. Van Herck, Jonas Weyler, Wilhelmus J. Kwanten, Eveline L. Dirinck, Benedicte Y. De Winter, Sven M. Francque, Luisa Vonghia
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Non-alcoholic fatty liver disease (NAFLD) constitutes a spectrum of disease states characterized by hepatic steatosis and is closely associated to obesity and the metabolic syndrome. In non-alcoholic steatohepatitis (NASH), additionally, inflammatory
Externí odkaz:
https://doaj.org/article/5bcf264b2e8d448f92dcf7344155958d
Autor:
Clémence M. Canivet, Ming-Hua Zheng, Sami Qadri, Luisa Vonghia, Kee-Huat Chuah, Charlotte Costentin, Jacob George, Angelo Armandi, Leon A. Adams, Naomi F. Lange, Odile Blanchet, Valérie Moal, Ramy Younes, Marine Roux, Wah-Kheong Chan, Nathalie Sturm, Mohammed Eslam, Elisabetta Bugianesi, Zhengyi Wang, Jean-François Dufour, Sven Francque, Hannele Yki-Järvinen, Kenneth I. Zheng, Jérôme Boursier
Publikováno v:
Clinical Gastroenterology and Hepatology.
Autor:
Luigi Buonaguro, Hans-Georg Rammensee, Harpreet Singh-Jasuja, Roberto S. Accolla, Toni Weinschenk, Carsten Reinhardt, Ulrike Gnad-Vogt, Mercedes Iñarrairaegui, Roberta Penta, Caterina Fusco, Maria Tagliamonte, Greta Forlani, Cécile Gouttefangeas, Regina Heidenreich, Tanguy Chaumette, Danila Valmori, Marco Borrelli, Heiko Schuster, Regina Mendrzyk, Katrin Aslan, Christian Flohr, Diego Duarte Alcoba, Jörg Ludwig, Antonio Avallone, Alessandro Inno, Luisa Vonghia, Sven Francque, Bruno Sangro, Yuk Ting Ma, Alfred Königsrainer, Paolo A. Ascierto, Andrea Mayer-Mokler, Francesco Izzo, Stefania Gori, Markus W. Löffler
Purpose:Immunotherapy for hepatocellular carcinoma (HCC) shows considerable promise in improving clinical outcomes. HepaVac-101 represents a single-arm, first-in-human phase I/II multicenter cancer vaccine trial for HCC (NCT03203005). It combines mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72da2ecb08d0ce79371835731a463971
https://doi.org/10.1158/1078-0432.c.6532524.v1
https://doi.org/10.1158/1078-0432.c.6532524.v1
Autor:
Luigi Buonaguro, Hans-Georg Rammensee, Harpreet Singh-Jasuja, Roberto S. Accolla, Toni Weinschenk, Carsten Reinhardt, Ulrike Gnad-Vogt, Mercedes Iñarrairaegui, Roberta Penta, Caterina Fusco, Maria Tagliamonte, Greta Forlani, Cécile Gouttefangeas, Regina Heidenreich, Tanguy Chaumette, Danila Valmori, Marco Borrelli, Heiko Schuster, Regina Mendrzyk, Katrin Aslan, Christian Flohr, Diego Duarte Alcoba, Jörg Ludwig, Antonio Avallone, Alessandro Inno, Luisa Vonghia, Sven Francque, Bruno Sangro, Yuk Ting Ma, Alfred Königsrainer, Paolo A. Ascierto, Andrea Mayer-Mokler, Francesco Izzo, Stefania Gori, Markus W. Löffler
Supplementary Data from Phase I/II Multicenter Trial of a Novel Therapeutic Cancer Vaccine, HepaVac-101, for Hepatocellular Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974db9314e1841dc5d5fb343fce288cc
https://doi.org/10.1158/1078-0432.22487466.v1
https://doi.org/10.1158/1078-0432.22487466.v1
Autor:
Cédric Peleman, Winnok H. De Vos, Isabel Pintelon, Ann Driessen, Annelies Van Eyck, Christophe Van Steenkiste, Luisa Vonghia, Joris De Man, Benedicte Y. De Winter, Tom Vanden Berghe, Sven M. Francque, Wilhelmus J. Kwanten
Publikováno v:
Virchows archiv
Immunohistochemical stains (IHC) reveal differences between liver lobule zones in health and disease, including nonalcoholic fatty liver disease (NAFLD). However, such differences are difficult to accurately quantify. In NAFLD, the presence of lipid