Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Luisa Massai"'
Autor:
Martina Carducci, Luisa Massai, Elisa Lari, Bianca Semplici, Silvia Grappi, Noshi Maria, Elizabeth Jones, Valentino Conti, Pietro Piu, Francesco Berlanda Scorza, Miren Iturriza-Gómara, Emanuele Montomoli, Andrew J. Pollard, Simona Rondini, Omar Rossi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Typhoid and Paratyphoid fever cause a global health burden, especially for the children of Southern Asia. The impact of the disease is further exacerbated by the dramatic increase of antimicrobial resistance. While vaccines against Salmonella Typhi h
Externí odkaz:
https://doaj.org/article/b7b4907e12864434a21755f9e18c093e
Autor:
Martina Carducci, Luisa Massai, Elisa Lari, Bianca Semplici, Maria Grazia Aruta, Daniele De Simone, Pietro Piu, Emanuele Montomoli, Francesco Berlanda Scorza, Silvia Grappi, Miren Iturriza-Gómara, Rocio Canals, Simona Rondini, Omar Rossi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Effective vaccines against Salmonella Typhi, targeting the Vi capsular polysaccharide, have been developed and are being introduced into routine immunization in endemic countries. Vi conjugated vaccines are also being tested in new multi-component va
Externí odkaz:
https://doaj.org/article/59c624cffe464ee7be797fd26c190bbf
Autor:
Gianmarco Gasperini, Luisa Massai, Daniele De Simone, Maria Michelina Raso, Elena Palmieri, Renzo Alfini, Omar Rossi, Neil Ravenscroft, Michelle M. Kuttel, Francesca Micoli
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionDifferent serovars of Salmonella enterica cause systemic diseases in humans including enteric fever, caused by S. Typhi and S. Paratyphi A, and invasive nontyphoidal salmonellosis (iNTS), caused mainly by S. Typhimurium and S. Enteritidis
Externí odkaz:
https://doaj.org/article/35cad51a0ebe43bea77726b50d883391
Autor:
Davide Oldrini, Roberta Di Benedetto, Martina Carducci, Daniele De Simone, Luisa Massai, Renzo Alfini, Barbara Galli, Brunella Brunelli, Amanda Przedpelski, Joseph T. Barbieri, Omar Rossi, Carlo Giannelli, Rino Rappuoli, Francesco Berti, Francesca Micoli
Publikováno v:
Vaccines, Vol 11, Iss 12, p 1770 (2023)
Glycoconjugate vaccines play a major role in the prevention of infectious diseases worldwide, with significant impact on global health, enabling the polysaccharides to induce immunogenicity in infants and immunological memory. Tetanus toxoid (TT), a
Externí odkaz:
https://doaj.org/article/dc3558a323a5433b8ca23f7e05639875
Autor:
Alexander J. Keeley, Martina Carducci, Luisa Massai, Mariagrazia Pizza, Thushan I. de Silva, Danilo G. Moriel, Omar Rossi
Publikováno v:
Methods and Protocols, Vol 5, Iss 4, p 55 (2022)
The measurement of antibodies to vaccine antigens is crucial for research towards a safe and effective vaccine for Streptococcus pyogenes (Strep A). We describe the establishment and detailed characterisation of a four-plex assay to measure IgG to th
Externí odkaz:
https://doaj.org/article/73f8986c6fdd4c25b0809c422598ed19
Autor:
Elena Palmieri, Zoltán Kis, James Ozanne, Roberta Di Benedetto, Beatrice Ricchetti, Luisa Massai, Martina Carducci, Davide Oldrini, Gianmarco Gasperini, Maria Grazia Aruta, Omar Rossi, Cleo Kontoravdi, Nilay Shah, Fatme Mawas, Francesca Micoli
Publikováno v:
Vaccines, Vol 10, Iss 7, p 1034 (2022)
Group A Streptococcus (GAS) causes about 500,000 annual deaths globally, and no vaccines are currently available. The Group A Carbohydrate (GAC), conserved across all GAS serotypes, conjugated to an appropriate carrier protein, represents a promising
Externí odkaz:
https://doaj.org/article/51ad062515b741b4afe2d444e2ee2b4a
Autor:
Vanessa Arato, Davide Oldrini, Luisa Massai, Gianmarco Gasperini, Francesca Necchi, Francesca Micoli
Publikováno v:
Microorganisms, Vol 9, Iss 11, p 2360 (2021)
Shigellosis is a diarrheal disease caused prevalently by Shigella flexneri and S. sonnei and representing a major global health risk, particularly in developing countries. Bacterial O-antigen (OAg) is the primary target of the host immune response an
Externí odkaz:
https://doaj.org/article/6c2d235a723a49bb93a91981c21a43de
Autor:
Giovanna Tripepi, Ruth Farmer, Salman Haider, Monika Rudzińska, G Westerberg, Sebastian Brzozy, Karin Schiefele, Elisa Mori, Letizia Magnoni, Michael Orth, Sarah J. Tabrizi, Ralph Andre, Marco Di Bacco, Carsten Saft, Danuta Ryglewicz, Giuseppe Pollio, Daniela Diamanti, Chris Frost, Claus A. Andersen, Sigurd D. Süssmuth, Enrica Diodato, Luisa Massai, Jens Dreyhaupt, Claudia Lamanna, Anna Baran, Borje Darpo, David Craufurd, G. Bernhard Landwehrmeyer
Publikováno v:
British Journal of Clinical Pharmacology. 79:465-476
AIMS: Selisistat, a selective SirT1 inhibitor is being developed as a potentially disease-modifying therapeutic for Huntington's disease (HD). This was the first study of selisistat in HD patients and was primarily aimed at development of pharmacodyn
Autor:
Cesare Federico, Andrea Caricasole, Letizia Magnoni, Wolfgang Fecke, Valentina Porcari, Freddy Heitz, Giulia Lazzeroni, Salvatore La Rosa, Luisa Massai, Tiziana Benicchi, Lara Rossini, Daniela Diamanti
Publikováno v:
SLAS Discovery. 18:984-996
Huntington's Disease is a rare neurodegenerative disease caused by an abnormal expansion of CAG repeats encoding polyglutamine in the first exon of the huntingtin gene. N-terminal fragments containing polyglutamine (polyQ) sequences aggregate and can
Autor:
Silvia Valensin, Enrica Diodato, Elena Pilli, Carla Scali, Luisa Massai, Roberta Magrini, Riccardo Roggeri, Antonella De Rosa, Fabio A. Recchia, Nicola P. Caradonna, Sara Chellini, Giuseppe Pollio, Patrizia Tunici, Valentina Porcari, Gianluca Sardone, Pasquale Fiengo, Letizia Magnoni, Silvia Coniglio, Vincenzo Lionetti, Daniela Diamanti, Martina Monti, Marco Rossi
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 86
Preclinical imaging modalities represent an essential tool to develop a modern and translational biomedical research. To date, Optical Imaging (OI) and Magnetic Resonance Imaging (MRI) are used principally in separate studies for molecular imaging st