Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Luisa M Villar"'
Autor:
Sunny Malhotra, Nicolas Fissolo, Carmen Rodríguez‐Rivera, Enric Monreal, Marta Montpeyo, Elena Urcelay, Juan Carlos Triviño, María José Pérez‐García, Miguel F. Segura, Agustín Pappolla, Jordi Río, Andreu Vilaseca, José Ignacio Fernández Velasco, Andrés Miguez, Carlos Goicoechea, Marta Martinez‐Vicente, Luisa M Villar, Xavier Montalban, Manuel Comabella
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 4, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/c4c6c2fc280e4866a272562127ef32f3
Autor:
Clara Matute‐Blanch, Verónica Brito, Luciana Midaglia, Luisa M Villar, Gerardo Garcia‐Diaz Barriga, Alerie Guzman de la Fuente, Eva Borrás, Sara Fernández‐García, Laura Calvo‐Barreiro, Andrés Miguez, Lucienne Costa‐Frossard, Rucsanda Pinteac, Eduard Sabidó, Jordi Alberch, Denise C. Fitzgerald, Xavier Montalban, Manuel Comabella
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 5, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/22aae93ec6d340e08088ba3607c7666c
Autor:
Miguel A Ortiz, Concepción Núñez, David Ordóñez, José C Alvarez-Cermeño, José E Martínez-Rodriguez, Antonio J Sánchez, Rafael Arroyo, Guillermo Izquierdo, Sunny Malhotra, Xavier Montalban, Antonio García-Merino, Elvira Munteis, Antonio Alcina, Manuel Comabella, Fuencisla Matesanz, Luisa M Villar, Elena Urcelay
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134414 (2015)
Multiple sclerosis (MS) is a neurodegenerative, autoimmune disease of the central nervous system. Genome-wide association studies (GWAS) have identified over hundred polymorphisms with modest individual effects in MS susceptibility and they have conf
Externí odkaz:
https://doaj.org/article/71212e472792411cbda73856ca44fc86
Autor:
Emilio G de la Concha, María L Cavanillas, M Carmen Cénit, Elena Urcelay, Rafael Arroyo, Óscar Fernández, José C Álvarez-Cermeño, Laura Leyva, Luisa M Villar, Concepción Núñez
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31018 (2012)
BackgroundMultiple sclerosis (MS) is a multifactorial disease with a genetic basis. The strongest associations with the disease lie in the Human Leukocyte Antigen (HLA) region. However, except for the DRB1*15:01 allele, the main risk factor associate
Externí odkaz:
https://doaj.org/article/3dd05502b42c46fda715be6281f7c052
Autor:
José I. Fernández-Velasco, Enric Monreal, Jens Kuhle, Virginia Meca-Lallana, José Meca-Lallana, Guillermo Izquierdo, Celia Oreja-Guevara, Francisco Gascón-Giménez, Susana Sainz de la Maza, Paulette E. Walo-Delgado, Paloma Lapuente-Suanzes, Aleksandra Maceski, Eulalia Rodríguez-Martín, Ernesto Roldán, Noelia Villarrubia, Albert Saiz, Yolanda Blanco, Carolina Diaz-Pérez, Gabriel Valero-López, Judit Diaz-Diaz, Yolanda Aladro, Luis Brieva, Cristina Íñiguez, Inés González-Suárez, Luis A Rodríguez de Antonio, José M. García-Domínguez, Julia Sabin, Sara Llufriu, Jaime Masjuan, Lucienne Costa-Frossard, Luisa M. Villar
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
ObjectiveTo ascertain the role of inflammation in the response to ocrelizumab in primary-progressive multiple sclerosis (PPMS).MethodsMulticenter prospective study including 69 patients with PPMS who initiated ocrelizumab treatment, classified accord
Externí odkaz:
https://doaj.org/article/c8e040513ca84c5f9b5252521e717dd6
Autor:
Silvia Pérez-Pérez, María Inmaculada Domínguez-Mozo, Aitana Alonso-Gómez, Silvia Medina, Noelia Villarrubia, Jose Ignacio Fernández-Velasco, María Ángel García-Martínez, Estefanía García-Calvo, Héctor Estévez, Lucienne Costa-Frossard, Jose C. Alvarez-Cermeño, Jose L. Luque-Garcia, Rafael Arroyo, Luisa M. Villar, Roberto Alvarez-Lafuente
Publikováno v:
PeerJ, Vol 8, p e10220 (2020)
Background Gut microbiota has been related to multiple sclerosis (MS) etiopathogenesis. Short-chain fatty acids (SCFA) are compounds derived from microbial metabolism that have a role in gut-brain axis. Objectives To analyse SCFA levels in plasma of
Externí odkaz:
https://doaj.org/article/3ba026cb7c13414f92934cd5c0344f11
Autor:
Eulalia Rodríguez-Martín, Israel Nieto-Gañán, Borja Hernández-Breijo, Cristina Sobrino, Carlota García-Hoz, Javier Bachiller, Ana Martínez-Feito, Victoria Navarro-Compán, Paloma Lapuente-Suanzes, Gema Bonilla, Dora Pascual-Salcedo, Garbiñe Roy, Teresa Jurado, Pilar Nozal, Mónica Vázquez-Díaz, Alejandro Balsa, Luisa M. Villar, Chamaida Plasencia-Rodríguez
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background: TNF inhibitors (TNFis) are widely used for the treatment of rheumatoid arthritis (RA), although the response rates to this therapy in patients with RA remains heterogeneous and < 50% achieve remission (REM).Objective: To analyze baseline
Externí odkaz:
https://doaj.org/article/699858df7a47431b9c7031068b0d7145
Autor:
Sunny Malhotra, Luisa M. Villar, Carme Costa, Luciana Midaglia, Marta Cubedo, Silvia Medina, Nicolás Fissolo, Jordi Río, Joaquín Castilló, José C. Álvarez-Cermeño, Alex Sánchez, Xavier Montalban, Manuel Comabella
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-12 (2018)
Abstract Background Recent studies in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis (MS), suggest an involvement of the histone methyltransferase enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2) in i
Externí odkaz:
https://doaj.org/article/f21896309ff34ead9be840d1b1d34a05
Autor:
Elia Gil-Varea, Elena Urcelay, Carles Vilariño-Güell, Carme Costa, Luciana Midaglia, Fuencisla Matesanz, Alfredo Rodríguez-Antigüedad, Jorge Oksenberg, Laura Espino-Paisan, A. Dessa Sadovnick, Albert Saiz, Luisa M. Villar, Juan Antonio García-Merino, Lluís Ramió-Torrentà, Juan Carlos Triviño, Ester Quintana, René Robles, Antonio Sánchez-López, Rafael Arroyo, Jose C. Alvarez-Cermeño, Angela Vidal-Jordana, Sunny Malhotra, Nicolas Fissolo, Xavier Montalban, Manuel Comabella
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-10 (2018)
Abstract Background It remains unclear whether disease course in multiple sclerosis (MS) is influenced by genetic polymorphisms. Here, we aimed to identify genetic variants associated with benign and aggressive disease courses in MS patients. Methods
Externí odkaz:
https://doaj.org/article/833c0146c0374957a77d4180572e95c7
Autor:
Estefania Garcia-Calvo, María Luisa Martínez Ginés, Silvia Medina Heras, José Ignacio Fernández Velasco, Hector Estevez, Haydee Goicochea Briceño, Juan De León-Luis, José Manuel García Domínguez, Ariana Meldaña Rivera, Silvia Pérez-Pérez, Juan Pablo Cuello, Roberto Alvarez-Lafuente, Amalia Tejeda-Velarde, María Ángel García-Martínez, Yolanda Higueras, Jose L. Luque-Garcia, Alberto Lozano Ros, Luisa M. Villar, Santiago Garcia-Tizon, Beatriz Pardo-Rodríguez, Maria Inmaculada Dominguez-Mozo
Publikováno v:
European Journal of Neurology. 29:895-900
Short-chain fatty acids (SCFAs) can have pro- or anti-inflammatory properties, but their relationship with multiple sclerosis (MS) relapses during pregnancy remains unknown. This study aimed to explore SCFA profiles in MS patients during pregnancy an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e61926f2cfefd3cda260b76622c0c303
https://doi.org/10.1111/ene.15150
https://doi.org/10.1111/ene.15150