Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Luisa Lundin"'
Autor:
Anna-Lena Heins, Ted Johanson, Shanshan Han, Luisa Lundin, Magnus Carlquist, Krist V. Gernaey, Søren J. Sørensen, Anna Eliasson Lantz
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Microbial cells in bioprocesses are usually described with averaged parameters. But in fact, single cells within populations vary greatly in characteristics such as stress resistance, especially in response to carbon source gradients. Our aim was to
Externí odkaz:
https://doaj.org/article/77623e11a0a746b8adf2c497d76d7a4a
Autor:
Anna-Lena Heins, Inês Nunes, Krist V. Gernaey, Luisa Lundin, Søren J. Sørensen, Anna Eliasson Lantz
Publikováno v:
Heins, A-L, Lundin, L, Nunes, I, Gernaey, K V, Sørensen, S J & Eliasson Lantz, A 2019, ' The effect of acetate on population heterogeneity in different cellular characteristics of Escherichia coli in aerobic batch cultures ', Biotechnology Progress, vol. 35, no. 3, e2796 . https://doi.org/10.1002/btpr.2796
Acetate as the major by-product in industrial scale bioprocesses with E. coli is found to decrease process efficiency as well as to be toxic to cells, which has several effects like a significant induction of cellular stress responses. However, the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a1b705e8bb4b1dc2d6fd062c428f6a
https://orbit.dtu.dk/en/publications/57f619d9-fc0e-44b1-a8d3-ff20a54db7fb
https://orbit.dtu.dk/en/publications/57f619d9-fc0e-44b1-a8d3-ff20a54db7fb
Autor:
Abhishek Dutta, Anna-Lena Heins, Luisa Lundin, Magnus Carlquist, Ingmar Nopens, Søren J. Sørensen, Anker Degn Jensen, Krist V. Gernaey, Rita Lencastre Fernandes, Anna Eliasson Lantz
Publikováno v:
Biotechnology and Bioengineering. 110:812-826
Despite traditionally regarded as identical, cells in a microbial cultivation present a distribution of phenotypic traits, forming a heterogeneous cell population. Moreover, the degree of heterogeneity is notably enhanced by changes in micro-environm
Autor:
Klaus Qvortrup, Michael Kühl, Anthony W. D. Larkum, Luisa Lundin, Søren J. Sørensen, Verena Schrameyer, Lars Behrendt
Publikováno v:
Applied and environmental microbiology. 78(11)
The cyanobacterium Acaryochloris marina is the only known phototroph harboring chlorophyll (Chl) d . It is easy to cultivate it in a planktonic growth mode, and A. marina cultures have been subject to detailed biochemical and biophysical characteriza
Publikováno v:
Schalén, M, Johanson, T, Lundin, L, Sørensen, S & Eliasson Lantz, A 2012, ' Heterogeneity in recombinant protein production ', New Biotechnology, vol. 29S, pp. S78 . https://doi.org/10.1016/j.nbt.2012.08.217
A crucial step in biotechnology is the scale-up process. Normally, lab scale verification and optimization of production processes and strains are performed in small reactors with perfect mixing andhence the cells experience a homogenous environment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0615cd7e58752b62d6c76ebe39971da
https://orbit.dtu.dk/en/publications/fe7bde36-a8fd-41fd-a5e3-96a71d5a2135
https://orbit.dtu.dk/en/publications/fe7bde36-a8fd-41fd-a5e3-96a71d5a2135
Autor:
Anna-Lena Heins, Søren J. Sørensen, Luisa Lundin, Magnus Carlquist, Krist V. Gernaey, Anna Eliasson Lantz, Rita Lencastre Fernandes, Søren Helmark
Publikováno v:
Carlquist, M, Fernandes, R L, Helmark, S, Heins, A-L, Lundin, L, Sorensen, S J, Gernaey, K & Eliasson Lantz, A 2012, ' Physiological heterogeneities in microbial populations and implications for physical stress tolerance ', Microbial Cell Factories, vol. 11, no. 94 . https://doi.org/10.1186/1475-2859-11-94
Microbial Cell Factories, Vol 11, Iss 1, p 94 (2012)
Scopus-Elsevier
Carlqvist, M, Lencastre Fernandes, R, Helmark, S, Heins, A-L, Neves Lundin, A L, Sørensen, S J, Gernaey, K & Eliasson Lantz, A 2012, ' Physiological heterogeneities in microbial populations and implications for physical stress tolerance ', Microbial Cell Factories, vol. 11, no. 94 . https://doi.org/10.1186/1475-2859-11-94
Microbial Cell Factories
Microbial Cell Factories, Vol 11, Iss 1, p 94 (2012)
Scopus-Elsevier
Carlqvist, M, Lencastre Fernandes, R, Helmark, S, Heins, A-L, Neves Lundin, A L, Sørensen, S J, Gernaey, K & Eliasson Lantz, A 2012, ' Physiological heterogeneities in microbial populations and implications for physical stress tolerance ', Microbial Cell Factories, vol. 11, no. 94 . https://doi.org/10.1186/1475-2859-11-94
Microbial Cell Factories
Background Traditionally average values of the whole population are considered when analysing microbial cell cultivations. However, a typical microbial population in a bioreactor is heterogeneous in most phenotypes measurable at a single-cell level.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6893c2723d2d6416984a22ad9efb62
https://orbit.dtu.dk/en/publications/8c9532b8-2baa-4331-b3d3-2229c0c4988a
https://orbit.dtu.dk/en/publications/8c9532b8-2baa-4331-b3d3-2229c0c4988a
Autor:
Rita Lencastre Fernandes, Anna-Lena Heins, Krist V. Gernaey, Anna Eliasson Lantz, Magnus Carlquist, Luisa Lundin, Søren J. Sørensen
Publikováno v:
Heins, A-L, Lencastre Fernandes, R, Lundin, L, Carlquist, M, Sörensen, S, Gernaey, K & Eliasson Lantz, A 2012, ' Dynamics in population heterogeneity during batch and continuous fermentation of Saccharomyces cerevisiae ', New Biotechnology, vol. 29S, pp. S199-S200 . https://doi.org/10.1016/j.nbt.2012.08.561
Traditionally, microbial populations in optimization studies of fermentation processes have been considered homogeneous. However, research has shown that a typical microbial population in fermentation is heterogeneous. There are indications that this
Autor:
Rita Lencastre Fernandes, Magnus Carlquist, Luisa Lundin, Anna-Lena Heins, Abhishek Dutta, Ingmar Nopens, Anker Degn Jensen, Johansen, Søren J., Anna Eliasson Lantz, Krist Gernaey
Publikováno v:
Technical University of Denmark Orbit
Lencastre Fernandes, R, Carlquist, M, Lundin, L, Heins, A-L, Dutta, A, Nopens, I, Jensen, A D, Johansen, S J, Eliasson Lantz, A & Gernaey, K 2011, ' Heterogeneous Microbial Populations: Using Flow Cytometric Data for Building Dynamic Distributed Models ', 2011 AIChE Annual Meeting, Minneapolis, MN, United States, 16/10/2011-21/10/2011 . < http://aiche.confex.com/aiche/2011/webprogram/Paper236591.html >
Lencastre Fernandes, R, Carlquist, M, Lundin, L, Heins, A-L, Dutta, A, Nopens, I, Johansen, S J, Jensen, A D, Eliasson Lantz, A & Gernaey, K 2011, ' Heterogeneous Microbial Populations: using flow cytometric data for building dynamic distributed models ', 8th European Congress of Chemical Engineering, Berlin, Germany, 25/09/2011-29/09/2011 .
Lencastre Fernandes, R, Carlquist, M, Lundin, L, Heins, A-L, Dutta, A, Nopens, I, Jensen, A D, Johansen, S J, Eliasson Lantz, A & Gernaey, K 2011, ' Heterogeneous Microbial Populations: Using Flow Cytometric Data for Building Dynamic Distributed Models ', 2011 AIChE Annual Meeting, Minneapolis, MN, United States, 16/10/2011-21/10/2011 . < http://aiche.confex.com/aiche/2011/webprogram/Paper236591.html >
Lencastre Fernandes, R, Carlquist, M, Lundin, L, Heins, A-L, Dutta, A, Nopens, I, Johansen, S J, Jensen, A D, Eliasson Lantz, A & Gernaey, K 2011, ' Heterogeneous Microbial Populations: using flow cytometric data for building dynamic distributed models ', 8th European Congress of Chemical Engineering, Berlin, Germany, 25/09/2011-29/09/2011 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6083545120ab909cf7b8eb596b2e56b5
https://orbit.dtu.dk/en/publications/439533ec-3067-4ad6-be9c-fee973e25c99
https://orbit.dtu.dk/en/publications/439533ec-3067-4ad6-be9c-fee973e25c99