Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Luisa Luciani"'
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 11, Pp 1423-1435 (2014)
Abstract The recent precipitous rise in autoimmune diseases is placing an increasing clinical and economic burden on health systems worldwide. Current therapies are only moderately efficacious, often coupled with adverse side effects. Here, we show t
Externí odkaz:
https://doaj.org/article/04739aba818e4169bf664b660e0decfd
Autor:
Oxana Bereshchenko, Elena Mancini, Luisa Luciani, Adriana Gambardella, Carlo Riccardi, Claus Nerlov
Publikováno v:
Haematologica, Vol 97, Iss 9 (2012)
Pontin is a highly conserved DNA helicase/ATPase which is a component of several macromolecular complexes with functions that include DNA repair, telomere maintenance and tumor suppression. While Pontin is known to be essential in yeast, fruit flies
Externí odkaz:
https://doaj.org/article/1ce4d0a1b42e4795a15625e8f4fba986
Autor:
Maria E. Arcila, Friederike Pastore, Ross L. Levine, Stefan Kubicek, Andrei V. Krivtsov, Lennart Bastian, Alan Chramiec, Daniel Tovbin, Abby R. Weinstein, Mithat Gönen, Adriana Rodriguez Gonzalez, Yen K. Lieu, Jacob M. Rowe, Luisa Luciani, Christopher E. Mason, Richard Koche, Omar Abdel-Wahab, Kaitlyn Shank, Justin R. Cross, Siddhartha Mukherjee, Stephen D. Nimer, Benjamin H. Durham, Wolfgang R. Sperr, Abhinita Mohanty, Olga A. Guryanova, Evangelia Loizou, Elodie Pronier, Barbara Spitzer, Scott A. Armstrong, Gregor Hoermann, Francine E. Garrett-Bakelman, Anna Sophia McKenney, Elisabeth Paietta, Martin S. Tallman, Philipp B. Staber, Matthew D. Keller, Ari Melnick, Sharon A. Rivera, Chezi Ganzel
Publikováno v:
Nature Medicine. 22:1488-1495
Although the majority of patients with acute myeloid leukemia (AML) initially respond to chemotherapy, many of them subsequently relapse, and the mechanistic basis for AML persistence following chemotherapy has not been determined. Recurrent somatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c7ac432a91e673cc2fff05a53fd820
https://doi.org/10.1038/nm.4210
https://doi.org/10.1038/nm.4210
Akademický článek
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Autor:
Na Man, Pierre-Jacques Hamard, Haiming Xu, Luisa Luciani, Madhavi Tadi, Sarah Greenblatt, Guoyan Cheng, Fan Liu, Lan Wang, Fabiana Perna, Stephen D. Nimer
Publikováno v:
Journal of Clinical Investigation. 125:3532-3544
Epigenetic regulators play critical roles in normal hematopoiesis, and the activity of these enzymes is frequently altered in hematopoietic cancers. The major type II protein arginine methyltransferase PRMT5 catalyzes the formation of symmetric dimet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8dac83132c2d0d65300a537c9c3b648
https://doi.org/10.1172/jci81749
https://doi.org/10.1172/jci81749
Publikováno v:
EMBO Molecular Medicine
The recent precipitous rise in autoimmune diseases is placing an increasing clinical and economic burden on health systems worldwide. Current therapies are only moderately efficacious, often coupled with adverse side effects. Here, we show that recom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae3a2c2c2b08725b5bb28fb3eee9477
https://doi.org/10.15252/emmm.201303376
https://doi.org/10.15252/emmm.201303376
Publikováno v:
Clinical Journal of Oncology Nursing. Aug2011, Vol. 15 Issue 4, p404-410. 7p. 1 Diagram, 1 Chart.
Autor:
McQuirter, Megan1 megan.mcquirter@mail.mcgill.ca, Castiglia, Luisa Luciani2, Loiselle, Carmen G.3, Wong, Nora4
Publikováno v:
Oncology Nursing Forum. May2010, Vol. 37 Issue 3, p313-320. 8p. 2 Charts.
Publikováno v:
International Journal of Hematology. 97:198-209
Histone-modifying enzymes have recently been shown to play a central role in the regulation of both normal and malignant hematopoiesis. Post-translational modifications of histones and non-histone proteins underlies a regulatory complexity affecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a3b1bf0db0965bf79d3d5214fb084b
https://doi.org/10.1007/s12185-012-1247-y
https://doi.org/10.1007/s12185-012-1247-y
Autor:
Susan Hardman Moore, Elena Mancini, Sidinh Luc, Sten Eirik W. Jacobsen, Amit Grover, Kasper D. Rasmussen, Luisa Luciani, Alejandra Sanjuan-Pla, Daniel Bilbao, Dónal O'Carroll, Agnes Zay, Claus Nerlov
Publikováno v:
The EMBO Journal. 31:351-365
The transcription factors that control lineage specification of haematopoietic stem cells (HSCs) have been well described for the myeloid and lymphoid lineages, whereas transcriptional control of erythroid (E) and megakaryocytic (Mk) fate is less und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::741806053413154b64a9806d52a228e1
https://doi.org/10.1038/emboj.2011.390
https://doi.org/10.1038/emboj.2011.390