Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Luisa Ladel"'
Autor:
Wan Ying Tan, Snigdha Nagabhyrava, Olivia Ang-Olson, Paromita Das, Luisa Ladel, Bethsebie Sailo, Linda He, Anup Sharma, Nita Ahuja
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 6533-6565 (2024)
Technological advancements in cell-free DNA (cfDNA) liquid biopsy have triggered exponential growth in numerous clinical applications. While cfDNA-based liquid biopsy has made significant strides in personalizing cancer treatment, the exploration and
Externí odkaz:
https://doaj.org/article/8124cb36bd324af188310cb6d09c9176
Publikováno v:
Cells, Vol 12, Iss 15, p 1962 (2023)
Appendiceal cancers (AC) are a rare and heterogeneous group of malignancies. Historically, appendiceal neoplasms have been grouped with colorectal cancers (CRC), and treatment strategies have been modeled after CRC management guidelines due to their
Externí odkaz:
https://doaj.org/article/d6a9fa65ef5c4ea89dd331000ef92a82
Autor:
Simon Renders, Arthur Flohr Svendsen, Jasper Panten, Nicolas Rama, Maria Maryanovich, Pia Sommerkamp, Luisa Ladel, Anna Rita Redavid, Benjamin Gibert, Seka Lazare, Benjamin Ducarouge, Katharina Schönberger, Andreas Narr, Manon Tourbez, Bertien Dethmers-Ausema, Erik Zwart, Agnes Hotz-Wagenblatt, Dachuan Zhang, Claudia Korn, Petra Zeisberger, Adriana Przybylla, Markus Sohn, Simon Mendez-Ferrer, Mathias Heikenwälder, Maik Brune, Daniel Klimmeck, Leonid Bystrykh, Paul S. Frenette, Patrick Mehlen, Gerald de Haan, Nina Cabezas-Wallscheid, Andreas Trumpp
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Haematopoietic stem cells (HSCs) are characterized by their self-renewal potential and associated dormancy. Here the authors show that niche produced netrin-1 preserves HSC quiescence and self-renewal via neogenin-1, and that decline of netrin-1 prod
Externí odkaz:
https://doaj.org/article/3c2f87ae1c244f13b1b1ad0a9daad872
Autor:
Inge van der Werf, Phoebe K. Mondala, S. Kathleen Steel, Larisa Balaian, Luisa Ladel, Cayla N. Mason, Raymond H. Diep, Jessica Pham, Jacqueline Cloos, Gertjan J.L. Kaspers, Warren C. Chan, Adam Mark, James J. La Clair, Peggy Wentworth, Kathleen M. Fisch, Leslie A. Crews, Thomas C. Whisenant, Michael D. Burkart, Mary E. Donohoe, Catriona H.M. Jamieson
Publikováno v:
Cell reports. Medicine, vol 4, iss 3
Cell reports. Medicine, 4(3):100962. Cell Press
Cell Reports Medicine, 4(3):100962. Cell Press
van der Werf, I, Mondala, P K, Steel, S K, Balaian, L, Ladel, L, Mason, C N, Diep, R H, Pham, J, Cloos, J, Kaspers, G J L, Chan, W C, Mark, A, la Clair, J J, Wentworth, P, Fisch, K M, Crews, L A, Whisenant, T C, Burkart, M D, Donohoe, M E & Jamieson, C H M 2023, ' Detection and targeting of splicing deregulation in pediatric acute myeloid leukemia stem cells ', Cell reports. Medicine, vol. 4, no. 3, 100962, pp. 100962 . https://doi.org/10.1016/j.xcrm.2023.100962, https://doi.org/10.1016/j.xcrm.2023.100962
Cell reports. Medicine, 4(3):100962. Cell Press
Cell Reports Medicine, 4(3):100962. Cell Press
van der Werf, I, Mondala, P K, Steel, S K, Balaian, L, Ladel, L, Mason, C N, Diep, R H, Pham, J, Cloos, J, Kaspers, G J L, Chan, W C, Mark, A, la Clair, J J, Wentworth, P, Fisch, K M, Crews, L A, Whisenant, T C, Burkart, M D, Donohoe, M E & Jamieson, C H M 2023, ' Detection and targeting of splicing deregulation in pediatric acute myeloid leukemia stem cells ', Cell reports. Medicine, vol. 4, no. 3, 100962, pp. 100962 . https://doi.org/10.1016/j.xcrm.2023.100962, https://doi.org/10.1016/j.xcrm.2023.100962
Pediatric acute myeloid leukemia (pAML) is typified by high relapse rates and a relative paucity of somatic DNA mutations. Although seminal studies show that splicing factor mutations and mis-splicing fuel therapy-resistant leukemia stem cell (LSC) g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635fc2f87ba6c7bb45c6b2245e0c70ae
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85150286973&origin=inward
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85150286973&origin=inward
Publikováno v:
Cureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eef09dd5822b0327a9a4e01547ec408
https://doi.org/10.7759/cureus.35554
https://doi.org/10.7759/cureus.35554
Publikováno v:
Cureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e05ef9ebcde0c98695101834201b29d
https://doi.org/10.7759/cureus.35275
https://doi.org/10.7759/cureus.35275
Autor:
Leslie A. Crews, Wenxue Ma, Luisa Ladel, Jessica Pham, Larisa Balaian, S. Kathleen Steel, Phoebe K. Mondala, Raymond H. Diep, Christina N. Wu, Cayla N. Mason, Inge van der Werf, Isabelle Oliver, Eduardo Reynoso, Gabriel Pineda, Thomas C. Whisenant, Peggy Wentworth, James J. La Clair, Qingfei Jiang, Michael D. Burkart, Catriona H.M. Jamieson
Publikováno v:
Cell Stem Cell. 30:250-263.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::479f480adc67d87af29db08fbda10b67
https://doi.org/10.1016/j.stem.2023.01.008
https://doi.org/10.1016/j.stem.2023.01.008
Modeling Premalignant Transformation of Hematopoietic Stem Cells in a Nanobioreactor in Microgravity
Autor:
Luisa Ladel, Jessica Pham, Larissa Balaian, Kathleen Steel, Isabelle Oliver, Catriona Jamieson
Publikováno v:
Blood. 140:2982-2983
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53a5c0e7dcac4216035a192e7c38dea0
https://doi.org/10.1182/blood-2022-168138
https://doi.org/10.1182/blood-2022-168138
Autor:
Cayla Mason, Phoebe Mondala, Inge van der Werf, Ruben van Boxtel, Markus J van Roosmalen, Kathleen M. Fisch, Jacqueline Cloos, Adam Mark, Raymond Diep, Larisa Balaian, James J. La Clair, Leslie Crews, Gertjan J.L. Kaspers, Luisa Ladel, Catriona Jamieson, Warren C. W. Chan, Kathleen Steel, Thomas Whisenant, Peggy Wentworth, Mary Donohoe, Michael D. Burkart
Publikováno v:
Mondala, P, Van Der Werf, I, Balaian, L, Steel, K, Ladel, L, Mason, C, Diep, R, Cloos, J, Kaspers, G, van Roosmalen, M J, Van Boxtel, R, Chan, W, Mark, A, Donohoe, M, La Clair, J, Wentworth, P, Fisch, K, Crews, L A, Whisenant, T, Burkart, M & Jamieson, C 2021, ' Deregulation of Splicing in Pediatric Acute Myeloid Stem and Progenitor Cells ', Blood, vol. 138 . https://doi.org/10.1182/blood-2021-154120
Blood, 138. American Society of Hematology
Blood, 138. American Society of Hematology
Currently, the limited capacity of pediatric acute myeloid leukemia (AML) therapies to prevent recurrence has contributed to high mortality rates. While dormant self-renewing leukemia stem cells (LSCs) contribute to adult AML relapse, their role in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d410fc7237fa86fcd9dbbeb5e49ba660
https://doi.org/10.1182/blood-2021-154120
https://doi.org/10.1182/blood-2021-154120
Publikováno v:
Cancer Research. 82:899-899
Inflammatory cytokine responsive APOBEC3 cytidine deaminases have been studied extensively with regard to innate immunity and more recently during cancer evolution. However, the mechanisms by which the APOBEC3 enzymes promote cancer initiation and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c97864b0c9013f916f022cbfe095630e
https://doi.org/10.1158/1538-7445.am2022-899
https://doi.org/10.1158/1538-7445.am2022-899