Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Luisa Kirchhof"'
Autor:
Galip S. Aslan, Nicolas Jaé, Yosif Manavski, Youssef Fouani, Mariana Shumliakivska, Lisa Kettenhausen, Luisa Kirchhof, Stefan Günther, Ariane Fischer, Guillermo Luxán, Stefanie Dimmeler
Publikováno v:
JCI Insight, Vol 8, Iss 5 (2023)
The adult mammalian heart has limited regenerative capacity, while the neonatal heart fully regenerates during the first week of life. Postnatal regeneration is mainly driven by proliferation of preexisting cardiomyocytes and supported by proregenera
Externí odkaz:
https://doaj.org/article/de92bfaf9053435ab34820620bb4c740
Autor:
D. Julia Trembinski, Diewertje I. Bink, Kosta Theodorou, Janina Sommer, Ariane Fischer, Anke van Bergen, Chao-Chung Kuo, Ivan G. Costa, Christoph Schürmann, Matthias S. Leisegang, Ralf P. Brandes, Tijna Alekseeva, Boris Brill, Astrid Wietelmann, Christopher N. Johnson, Alexander Spring-Connell, Manuel Kaulich, Stanislas Werfel, Stefan Engelhardt, Marc N. Hirt, Kaja Yorgan, Thomas Eschenhagen, Luisa Kirchhof, Patrick Hofmann, Nicolas Jaé, Ilka Wittig, Nazha Hamdani, Corinne Bischof, Jaya Krishnan, Riekelt H. Houtkooper, Stefanie Dimmeler, Reinier A. Boon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Aging induces cardiovascular disease, but which RNA molecules control cardiac aging is poorly understood. Here the authors identified the aging-regulated non-coding RNA Sarrah, which controls cardiomyocyte survival and cardiac function by inducing ca
Externí odkaz:
https://doaj.org/article/7441973a82494a94a2d3de6efa08b38c
Autor:
Luisa Kirchhof, Youssef Fouani, Andrea Knau, Galip S. Aslan, Andreas W. Heumüller, Ilka Wittig, Michaela Müller-McNicoll, Stefanie Dimmeler, Nicolas Jaé
Publikováno v:
Non-Coding RNA, Vol 8, Iss 4, p 49 (2022)
Besides transcription, RNA decay accounts for a large proportion of regulated gene expression and is paramount for cellular functions. Classical RNA surveillance pathways, like nonsense-mediated decay (NMD), are also implicated in the turnover of non
Externí odkaz:
https://doaj.org/article/3681f3c4343c4f76aafc9969bd83bf69
Autor:
Youssef Fouani, Luisa Kirchhof, Laura Stanicek, Guillermo Luxán, Andreas W Heumüller, Andrea Knau, Ariane Fischer, Kavi Devraj, David John, Philipp Neumann, Albrecht Bindereif, Reinier A Boon, Stefan Liebner, Ilka Wittig, Carolin Mogler, Madina Karimova, Stefanie Dimmeler, Nicolas Jaé
Publikováno v:
Fouani, Y, Kirchhof, L, Stanicek, L, Luxán, G, Heumüller, A W, Knau, A, Fischer, A, Devraj, K, John, D, Neumann, P, Bindereif, A, Boon, R A, Liebner, S, Wittig, I, Mogler, C, Karimova, M, Dimmeler, S & Jaé, N 2022, ' The splicing-regulatory lncRNA NTRAS sustains vascular integrity ', EMBO Reports, vol. 23, no. 6, e54157 . https://doi.org/10.15252/embr.202154157
EMBO Reports, 23(6):e54157. Wiley-Blackwell
EMBO Reports, 23(6):e54157. Wiley-Blackwell
Vascular integrity is essential for organ homeostasis to prevent edema formation and infiltration of inflammatory cells. Long non-coding RNAs (lncRNAs) are important regulators of gene expression and often expressed in a cell type-specific manner. By
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c295c45214d91ab118cffea2c6c722
http://www.scopus.com/inward/record.url?scp=85129457571&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85129457571&partnerID=8YFLogxK
Autor:
Boris Brill, Matthias S. Leisegang, Luisa Kirchhof, Tijna Alekseeva, Astrid Wietelmann, Kaja Yorgan, Stefanie Dimmeler, Jaya Krishnan, Stefan Engelhardt, Alexander M. Spring-Connell, Diewertje I. Bink, Marc N. Hirt, Corinne Bischof, Christopher N. Johnson, Anke van Bergen, Ralf P. Brandes, Janina Sommer, Riekelt H. Houtkooper, Thomas Eschenhagen, Ilka Wittig, Ariane Fischer, Chao-Chung Kuo, Nicolas Jaé, Manuel Kaulich, Patrick Hofmann, Stanislas Werfel, Ivan G. Costa, D. Julia Trembinski, Reinier A. Boon, Nazha Hamdani, Kosta Theodorou, Christoph Schürmann
Publikováno v:
Nature Communications, 11(1):2039. Nature Publishing Group UK
Nature Communications
Trembinski, D J, Bink, D I, Theodorou, K, Sommer, J, Fischer, A, van Bergen, A, Kuo, C C, Costa, I G, Schürmann, C, Leisegang, M S, Brandes, R P, Alekseeva, T, Brill, B, Wietelmann, A, Johnson, C N, Spring-Connell, A, Kaulich, M, Werfel, S, Engelhardt, S, Hirt, M N, Yorgan, K, Eschenhagen, T, Kirchhof, L, Hofmann, P, Jaé, N, Wittig, I, Hamdani, N, Bischof, C, Krishnan, J, Houtkooper, R H, Dimmeler, S & Boon, R A 2020, ' Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction ', Nature Communications, vol. 11, no. 1, 2039 . https://doi.org/10.1038/s41467-020-15995-2
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, 11(1):2039. Nature Publishing Group
Nature Communications
Trembinski, D J, Bink, D I, Theodorou, K, Sommer, J, Fischer, A, van Bergen, A, Kuo, C C, Costa, I G, Schürmann, C, Leisegang, M S, Brandes, R P, Alekseeva, T, Brill, B, Wietelmann, A, Johnson, C N, Spring-Connell, A, Kaulich, M, Werfel, S, Engelhardt, S, Hirt, M N, Yorgan, K, Eschenhagen, T, Kirchhof, L, Hofmann, P, Jaé, N, Wittig, I, Hamdani, N, Bischof, C, Krishnan, J, Houtkooper, R H, Dimmeler, S & Boon, R A 2020, ' Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction ', Nature Communications, vol. 11, no. 1, 2039 . https://doi.org/10.1038/s41467-020-15995-2
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, 11(1):2039. Nature Publishing Group
Long non-coding RNAs (lncRNAs) contribute to cardiac (patho)physiology. Aging is the major risk factor for cardiovascular disease with cardiomyocyte apoptosis as one underlying cause. Here, we report the identification of the aging-regulated lncRNA S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30d625577e97fb0a47fefa3a1339c0a
https://research.vumc.nl/en/publications/19dfbbe7-80a3-4a41-b4cb-98b9c8d2f34c
https://research.vumc.nl/en/publications/19dfbbe7-80a3-4a41-b4cb-98b9c8d2f34c
