Zobrazeno 1 - 10
of 281
pro vyhledávání: '"Luisa Iruela-Arispe"'
Autor:
Katiannah Moise, Keerthana M. Arun, Maalavika Pillai, Jocelynda Salvador, Aarya S. Mehta, Yogesh Goyal, M. Luisa Iruela-Arispe
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
The innermost layer of the vessel wall is constantly subjected to recurring and relenting mechanical forces by virtue of their direct contact with blood flow. Endothelial cells of the vessel are exposed to distension, pressure, and shear stress; adap
Externí odkaz:
https://doaj.org/article/ab337b5bc4f242bca97f8bd55cdac783
Autor:
Pierre J Guihard, Jiayi Yao, Ana M Blazquez-Medela, Luisa Iruela-Arispe, Kristina I Boström, Yucheng Yao
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167936 (2016)
Endothelial-mesenchymal transition (EndMT) drives endothelium to contribute to normal development and disease processes. Here, we report that EndMTs occur in the diabetic endothelium of Ins2Akita/wt mouse, and show that induction of sex determining r
Externí odkaz:
https://doaj.org/article/ce5ad2853d6f45e2a05b7676a07a7dd2
Autor:
Hannah L. Sunshine, Andrew C. Cicchetto, Karolina Elżbieta Kaczor-Urbanowicz, Feiyang Ma, Danielle Pi, Chloe Symons, Martin Turner, Vipul Shukla, Heather R. Christofk, Thomas A. Vallim, M. Luisa Iruela-Arispe
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113627- (2024)
Summary: Vascular morphogenesis requires a delicate gradient of Notch signaling controlled, in part, by the distribution of ligands (Dll4 and Jagged1). How Jagged1 (JAG1) expression is compartmentalized in the vascular plexus remains unclear. Here, w
Externí odkaz:
https://doaj.org/article/7d029b8ee1744027bfa8881e01ccbc7e
Autor:
M Luisa Iruela‐Arispe
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 5, Pp 1-3 (2023)
Abstract Retinopathy is one of the more severe complications associated with diabetes. Targeting vascular pathology has shown benefits, but current therapies are costly and have limitations. In this issue of EMBO Molecular Medicine, Niaudet et al rep
Externí odkaz:
https://doaj.org/article/c33fd922d10a4055b141df60fc298fb3
Autor:
Pearl Quijada, Shuin Park, Peng Zhao, Kamal S.S. Kolluri, David Wong, Kevin D. Shih, Kai Fang, Arash Pezhouman, Lingjun Wang, Ali Daraei, Matthew D. Tran, Elle M. Rathbun, Kimberly N. Burgos Villar, Maria L. Garcia-Hernandez, Thanh T.D. Pham, Charles J. Lowenstein, M. Luisa Iruela-Arispe, S. Thomas Carmichael, Eric M. Small, Reza Ardehali
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 10 (2023)
Despite the prevalence of pericytes in the microvasculature of the heart, their role during ischemia-induced remodeling remains unclear. We used multiple lineage-tracing mouse models and found that pericytes migrated to the injury site and expressed
Externí odkaz:
https://doaj.org/article/f18ebf825bbb4dbca6e73911d2a8ceaf
Autor:
Andrew C. Cicchetto, Elsie C. Jacobson, Hannah Sunshine, Blake R. Wilde, Abigail S. Krall, Kelsey E. Jarrett, Leslie Sedgeman, Martin Turner, Kathrin Plath, M. Luisa Iruela-Arispe, Thomas Q. de Aguiar Vallim, Heather R. Christofk
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112411- (2023)
Summary: Cellular metabolism is tightly regulated by growth factor signaling, which promotes metabolic rewiring to support growth and proliferation. While growth factor-induced transcriptional and post-translational modes of metabolic regulation have
Externí odkaz:
https://doaj.org/article/73e0963b38cb4fecacd111d48dec773f
Autor:
Yalda Afshar, Feyiang Ma, Austin Quach, Anhyo Jeong, Hannah L Sunshine, Vanessa Freitas, Yasaman Jami-Alahmadi, Raphael Helaers, Xinmin Li, Matteo Pellegrini, James A Wohlschlegel, Casey E Romanoski, Miikka Vikkula, M Luisa Iruela-Arispe
Publikováno v:
eLife, Vol 12 (2023)
Environmental cues, such as physical forces and heterotypic cell interactions play a critical role in cell function, yet their collective contributions to transcriptional changes are unclear. Focusing on human endothelial cells, we performed broad in
Externí odkaz:
https://doaj.org/article/f5af08e56062488ea026c573d9c0968d
Autor:
Jonathan Jung, Sarbjeet Niraula, James Du, Vivek Pamulapati, Jae Woong Jang, Liqun Xiong, M. Luisa Iruela-Arispe, Michael R. MacArthur, Karen J. Ho
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100144- (2023)
Externí odkaz:
https://doaj.org/article/fb06f15e57ce42d28f50f1e45b833953
Autor:
Salim Abdelilah-Seyfried, M. Luisa Iruela-Arispe, Josef M. Penninger, Elisabeth Tournier-Lasserve, Miikka Vikkula, Ondine Cleaver
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 8 (2022)
Externí odkaz:
https://doaj.org/article/ce136ec515304a3cbb8f606c26ea2b69
Autor:
Guibin Chen, Zhongwen Li, Yangtengyu Liu, Daniel Chen, Jeanette Beers, Cornelia Cudrici, Elisa A. Ferrante, Robin Schwartzbeck, Natalia Dmitrieva, Dan Yang, Jizhong Zou, M. Luisa Iruela-Arispe, Manfred Boehm
Publikováno v:
Stem Cell Research, Vol 45, Iss , Pp - (2020)
We have successfully generated induced pluripotent stem cell (iPSC) lines derived from peripheral blood mononuclear cells of five patients with Cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Thes
Externí odkaz:
https://doaj.org/article/01ba4ca4d3cd4344aec6e677eac4da37