Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Luisa Guttieri"'
Autor:
Luisa Guttieri, Salvatore Raffa, Gerardo Salerno, Rachele Bigi, Flavia Persechino, Vincenzo Visco, Maria Rosaria Torrisi, Danilo Ranieri, Francesca Belleudi
Publikováno v:
Biology, Vol 12, Iss 3, p 463 (2023)
Actinic keratosis (AK) is a preneoplastic skin disorder which can rapidly progress to cutaneous squamous cell carcinomas (SCCs). In light of our previous findings, indicating a possible oncogenic role of the mesenchymal isoform of FGFR2 (FGFR2c) aber
Externí odkaz:
https://doaj.org/article/b92bed79d0384e7ca4e4ffd83cec0fcd
Autor:
Danilo Ranieri, Deborah French, Flavia Persechino, Luisa Guttieri, Maria Rosaria Torrisi, Francesca Belleudi
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1652 (2022)
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy whose main characterizations are Kirsten Rat Sarcoma-activating mutations (KRAS) and a highly aggressive phenotype. Based on our recent findings demonstrating that the highly aberrant exp
Externí odkaz:
https://doaj.org/article/0feb8d631c1346e2acc385c15ac5e8b4
Autor:
Roberta Gonnella, Luisa Guttieri, Maria Saveria Gilardini Montani, Roberta Santarelli, Erica Bassetti, Gabriella D’Orazi, Mara Cirone
Publikováno v:
Biology, Vol 11, Iss 1, p 132 (2022)
We have previously shown that Zinc supplementation triggered ER stress/UPR in cancer cells undergoing treatment by genotoxic agents, reactivated wtp53 in cancer cells harboring mutant p53 (mutp53) and potentiated the activity of wtp53 in those carryi
Externí odkaz:
https://doaj.org/article/cb1bfdb101f94924a0ea1c325f1fb297
Autor:
Flavia Persechino, Danilo Ranieri, Luisa Guttieri, Monica Nanni, Maria Rosaria Torrisi, Francesca Belleudi
Publikováno v:
Biology, Vol 10, Iss 4, p 331 (2021)
Actinic keratosis (AK) is the ultra violet (UV)-induced preneoplastic skin lesion clinically classified in low (KIN I), intermediate (KIN II), and high (KIN III) grade lesions. In this work we analyzed the expression of Fibroblast Growth Factor Recep
Externí odkaz:
https://doaj.org/article/a58ccc5a0e6d402cad464db916010fc5
Autor:
Roberta Gonnella, Maria Saveria Gilardini Montani, Luisa Guttieri, Maria Anele Romeo, Roberta Santarelli, Mara Cirone
Publikováno v:
Biomedicines, Vol 9, Iss 2, p 118 (2021)
Primary Effusion Lymphoma (PEL) is a highly aggressive B cell lymphoma associated with Kaposi’s Sarcoma-associated Herpesvirus (KSHV). It is characterized by a high level of basal Endoplasmic Reticulum (ER) stress, Unfolded Protein Response (UPR) a
Externí odkaz:
https://doaj.org/article/ae41d5e0b9b44fbc972269cde911e9d7
Publikováno v:
Journal of Cellular and Molecular Medicine
Signalling of the epithelial splicing variant of fibroblast growth factor receptor 2 (FGFR2b) triggers both differentiation and autophagy, while the aberrant expression of the mesenchymal FGFR2c isoform in epithelial cells induces impaired differenti
Autor:
Danilo, Ranieri, Luisa, Guttieri, Salvatore, Raffa, Maria Rosaria, Torrisi, Francesca, Belleudi
Publikováno v:
Cancers
Simple Summary This work aims to assess the contribution of the aberrant expression of the mesenchymal FGFR2c and the triggering of the downstream PKCε signaling in selected cell lines from pancreatic ductal adenocarcinoma (PDAC), a malignancy chara
Autor:
Monica Nanni, Danilo Ranieri, Francesca Belleudi, Luisa Guttieri, Flavia Persechino, Maria Rosaria Torrisi
Publikováno v:
Biology, Vol 10, Iss 331, p 331 (2021)
Biology
Volume 10
Issue 4
Biology
Volume 10
Issue 4
Simple Summary In this work, we checked the modulation of Fibroblast Growth Factor Receptors (FGFRs) along with differentiation-related and epithelial-to-mesenchymal transition (EMT)-related markers to identify expression profiles that could be predi
Autor:
Danilo Ranieri, Deborah French, Francesca Belleudi, Salvatore Raffa, Luisa Guttieri, Maria Rosaria Torrisi
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 6534, p 6534 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 6534, p 6534 (2021)
Infection with human papillomavirus type 16 (HPV16) is one of the major risk factors for the development of cervical cancer. Our previous studies have demonstrated the involvement of the early oncoprotein E5 of HPV16 (16E5) in the altered isoform swi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0beb3137c1df1c619945e7590bc0b0
http://hdl.handle.net/11573/1563001
http://hdl.handle.net/11573/1563001
Publikováno v:
Cancers, Vol 13, Iss 4993, p 4993 (2021)
Cancers
Volume 13
Issue 19
Cancers
Volume 13
Issue 19
Pancreatic ductal adenocarcinoma (PDAC) is a treatment-resistant malignancy characterized by a high malignant phenotype including acquired EMT signature and deregulated autophagy. Since we have previously described that the aberrant expression of the