Výsledky vyhledávání - "Luisa Ganfini"

Akademický článek

Flow cytometry as an integrative method for the evaluation of vaccine immunogenicity: A validation approach

Autor: Elena Gianchecchi, Alessandro Torelli, Pietro Piu, Carolina Bonifazi, Luisa Ganfini, Emanuele Montomoli

Publikováno v: Biochemistry and Biophysics Reports, Vol 34, Iss , Pp 101472- (2023)

The applied bioanalytical assays used for the evaluation of human immune responses from samples collected during clinical trials must be well characterized, fully validated and properly documented to provide reliable results. Even though recommendati

Externí odkaz: https://doaj.org/article/8ec2b8f4437f455f9641a93778d81f99

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Akademický článek

Large scale validation of an efficient CRISPR/Cas-based multi gene editing protocol in Escherichia coli

Autor: Francesca Zerbini, Ilaria Zanella, Davide Fraccascia, Enrico König, Carmela Irene, Luca F. Frattini, Michele Tomasi, Laura Fantappiè, Luisa Ganfini, Elena Caproni, Matteo Parri, Alberto Grandi, Guido Grandi

Publikováno v: Microbial Cell Factories, Vol 16, Iss 1, Pp 1-18 (2017)

Abstract Background The exploitation of the CRISPR/Cas9 machinery coupled to lambda (λ) recombinase-mediated homologous recombination (recombineering) is becoming the method of choice for genome editing in E. coli. First proposed by Jiang and co-wor

Externí odkaz: https://doaj.org/article/d520ccc66f464bb5b5ee0df1acb851c0

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Akademický článek

Effect of Repeated Freeze–Thaw Cycles on Influenza Virus Antibodies

Autor: Alessandro Torelli, Elena Gianchecchi, Martina Monti, Pietro Piu, Irene Barneschi, Carolina Bonifazi, Rosa Coluccio, Luisa Ganfini, Luciano Michele La Magra, Silvia Marconi, Ginevra Marzucchi, Ramona Pace, Laura Palladino, Bernardo Biagi, Emanuele Montomoli

Publikováno v: Vaccines, Vol 9, Iss 3, p 267 (2021)

Background: Vaccine effectiveness relies on various serological tests, whose aim is the measurement of antibody titer in serum samples collected during clinical trials before and after vaccination. Among the serological assays required by the regulat

Externí odkaz: https://doaj.org/article/11671c17647546ada82fdc8d59d9f12d

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Akademický článek

Vaccination With a FAT1-Derived B Cell Epitope Combined With Tumor-Specific B and T Cell Epitopes Elicits Additive Protection in Cancer Mouse Models

Autor: Alberto Grandi, Laura Fantappiè, Carmela Irene, Silvia Valensin, Michele Tomasi, Simone Stupia, Riccardo Corbellari, Elena Caproni, Ilaria Zanella, Samine J. Isaac, Luisa Ganfini, Luca Frattini, Enrico König, Assunta Gagliardi, Simona Tavarini, Chiara Sammicheli, Matteo Parri, Guido Grandi

Publikováno v: Frontiers in Oncology, Vol 8 (2018)

Human FAT1 is overexpressed on the surface of most colorectal cancers (CRCs) and in particular a 25 amino acid sequence (D8) present in one of the 34 cadherin extracellular repeats carries the epitope recognized by mAb198.3, a monoclonal antibody whi

Externí odkaz: https://doaj.org/article/74c77bd15be14cdd8d66c6c26dcfa294

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Akademický článek

Synergistic Protective Activity of Tumor-Specific Epitopes Engineered in Bacterial Outer Membrane Vesicles

Autor: Alberto Grandi, Michele Tomasi, Ilaria Zanella, Luisa Ganfini, Elena Caproni, Laura Fantappiè, Carmela Irene, Luca Frattini, Samine J. Isaac, Enrico König, Francesca Zerbini, Simona Tavarini, Chiara Sammicheli, Fabiola Giusti, Ilaria Ferlenghi, Matteo Parri, Guido Grandi

Publikováno v: Frontiers in Oncology, Vol 7 (2017)

IntroductionBacterial outer membrane vesicles (OMVs) are naturally produced by all Gram-negative bacteria and, thanks to their plasticity and unique adjuvanticity, are emerging as an attractive vaccine platform. To test the applicability of OMVs in c

Externí odkaz: https://doaj.org/article/b400c8fb68a1468f880c0517dc5d919c

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Effect of Repeated Freeze–Thaw Cycles on Influenza Virus Antibodies

Autor: Ramona Pace, Elena Gianchecchi, Emanuele Montomoli, Silvia Marconi, Luciano Michele La Magra, Pietro Piu, Irene Barneschi, Carolina Bonifazi, Rosa Coluccio, Ginevra Marzucchi, Luisa Ganfini, Martina Monti, Laura Palladino, Alessandro Torelli, Bernardo Biagi

Publikováno v: Vaccines, Vol 9, Iss 267, p 267 (2021)
Vaccines
Volume 9
Issue 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32d310ec6b1a5bead3033cf23c2ac77
https://www.mdpi.com/2076-393X/9/3/267

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Large scale validation of an efficient CRISPR/Cas-based multi gene editing protocol in Escherichia coli

Autor: Ilaria Zanella, Guido Grandi, Michele Tomasi, Enrico König, Matteo Parri, Francesca Zerbini, Elena Caproni, Carmela Irene, Luca Frattini, Davide Fraccascia, Alberto Grandi, Luisa Ganfini, Laura Fantappiè

Publikováno v: Microbial Cell Factories
Microbial Cell Factories, Vol 16, Iss 1, Pp 1-18 (2017)

Background The exploitation of the CRISPR/Cas9 machinery coupled to lambda (λ) recombinase-mediated homologous recombination (recombineering) is becoming the method of choice for genome editing in E. coli. First proposed by Jiang and co-workers, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107d743abc7717f13d39232546bc41f2
http://europepmc.org/articles/PMC5404680

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Some Gram-negative Lipoproteins Keep Their Surface Topology When Transplanted from One Species to Another and Deliver Foreign Polypeptides to the Bacterial Surface

Autor: Guido Grandi, Serena Bonomi, Chiara Carnemolla, Michele Tomasi, Luisa Ganfini, Carmela Irene, Luca Bini, Assunta Gagliardi, Matteo Parri, Francesca Zerbini, Alberto Grandi, Valeria Cafardi, Laura Fantappiè, Alessandro Armini, Ilaria Zanella, Micaela de Santis

Publikováno v: Molecular & Cellular Proteomics : MCP

In Gram-negative bacteria, outer membrane-associated lipoproteins can either face the periplasm or protrude out of the bacterial surface. The mechanisms involved in lipoprotein transport through the outer membrane are not fully elucidated. Some lipop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac8b44e5efed89b9ec3c37bc61da6b2
http://hdl.handle.net/11365/1013080

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FAT1: a potential target for monoclonal antibody therapy in colon cancer

Autor: Luigi Terracciano, Alberto Grandi, Matteo Parri, Ilaria Naldi, Guido Grandi, Chaojun Song, Elisa De Camilli, Susanna Campagnoli, Boquan Jin, Renata Grifantini, Caterina Cinti, Luisa Ganfini, Giuseppe Viale, Piero Pileri, Aurelien Lacombe, Paolo Sarmientos

Publikováno v: British Journal of Cancer 114 (2016): 40–51. doi:10.1038/bjc.2016.145
info:cnr-pdr/source/autori:Piero Pileri, Susanna Campagnoli, Alberto Grandi, Matteo Parri, Elisa De Camilli, Chaojun Song, Luisa Ganfini, Aurelien Lacombe, Ilaria Naldi, Paolo Sarmientos, Caterina Cinti, Boquan Jin, Guido Grandi, Giuseppe Viale, Luigi Terracciano and Renata Grifantini/titolo:FAT1: a potential target for monoclonal antibody therapy in colon cancer/doi:10.1038%2Fbjc.2016.145/rivista:British Journal of Cancer/anno:2016/pagina_da:40/pagina_a:51/intervallo_pagine:40–51/volume:114
British Journal of Cancer

Background: Colorectal cancer (CRC) is one of the major causes of cancer-associated mortality worldwide. The currently approved therapeutic agents have limited efficacy. Methods: The atypical cadherin FAT1 was discovered as a novel CRC-associated pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a219c2251aa320cd105106c19535e8

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